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Pétur Orri Heiðarsson
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Extreme disorder in an ultrahigh-affinity protein complex
A Borgia, MB Borgia, K Bugge, VM Kissling, PO Heidarsson, ...
Nature 555 (7694), 61-66, 2018
6112018
Binding without folding–the biomolecular function of disordered polyelectrolyte complexes
B Schuler, A Borgia, MB Borgia, PO Heidarsson, ED Holmstrom, D Nettels, ...
Current opinion in structural biology 60, 66-76, 2020
762020
Polyelectrolyte interactions enable rapid association and dissociation in high-affinity disordered protein complexes
A Sottini, A Borgia, MB Borgia, K Bugge, D Nettels, A Chowdhury, ...
Nature communications 11 (1), 5736, 2020
692020
Direct single-molecule observation of calcium-dependent misfolding in human neuronal calcium sensor-1
PO Heidarsson, MM Naqvi, MR Otazo, A Mossa, BB Kragelund, ...
Proceedings of the National Academy of Sciences 111 (36), 13069-13074, 2014
612014
The C-terminal Tail of Human Neuronal Calcium Sensor 1 Regulates the Conformational Stability of the Ca< sup> 2+</sup>-Activated State
PO Heidarsson, IJ Bjerrum-Bohr, GA Jensen, O Pongs, BE Finn, ...
Journal of Molecular Biology 417 (1-2), 51-64, 2012
462012
Protein interacting with C-kinase 1 (PICK1) binding promiscuity relies on unconventional PSD-95/discs-large/ZO-1 homology (PDZ) binding modes for nonclass II PDZ ligands
S Erlendsson, M Rathje, PO Heidarsson, FM Poulsen, KL Madsen, ...
Journal of Biological Chemistry 289 (36), 25327-25340, 2014
432014
A Highly Compliant Protein Native State with a Spontaneous-like Mechanical Unfolding Pathway
PO Heidarsson, I Valpapuram, C Camilloni, A Imparato, G Tiana, ...
Journal of the American Chemical Society 134 (41), 17068-17075, 2012
362012
Release of linker histone from the nucleosome driven by polyelectrolyte competition with a disordered protein
PO Heidarsson, D Mercadante, A Sottini, D Nettels, MB Borgia, A Borgia, ...
Nature Chemistry 14 (2), 224-231, 2022
342022
Single-molecule folding mechanism of an EF-hand neuronal calcium sensor
PO Heidarsson, MR Otazo, L Bellucci, A Mossa, A Imparato, E Paci, ...
Structure 21 (10), 1812-1821, 2013
322013
Exploring the minimally frustrated energy landscape of unfolded ACBP
V Ozenne, JK Noel, PO Heidarsson, S Brander, FM Poulsen, MR Jensen, ...
Journal of Molecular Biology 426 (3), 722-734, 2014
252014
Multifunctional Intrinsically Disordered Regions in Transcription Factors
M Már, K Nitsenko, PO Heidarsson
Chemistry–A European Journal, 2023
202023
Single-molecule folding mechanisms of the apo-and Mg2+-bound states of human neuronal calcium sensor-1
MM Naqvi, PO Heidarsson, MR Otazo, A Mossa, BB Kragelund, ...
Biophysical journal 109 (1), 113-123, 2015
202015
Structural features and dynamics of a cold‐adapted alkaline phosphatase studied by EPR spectroscopy
PO Heidarsson, ST Sigurdsson, B Asgeirsson
The FEBS Journal 276 (10), 2725-2735, 2009
192009
Effects of ligand binding on the energy landscape of Acyl-CoA-binding protein
P Sonar, L Bellucci, A Mossa, PO Heidarsson, BB Kragelund, C Cecconi
Biophysical Journal 119 (9), 1821-1832, 2020
162020
Disordered proteins enable histone chaperoning on the nucleosome
PO Heidarsson, D Mercadante, A Sottini, D Nettels, MB Borgia, A Borgia, ...
BioRxiv, 2020.04. 17.046243, 2020
132020
Solution properties of the archaeal CRISPR DNA repeat-binding homeodomain protein Cbp2
CS Kenchappa, PO Heidarsson, BB Kragelund, RA Garrett, FM Poulsen
Nucleic acids research 41 (5), 3424-3435, 2013
122013
From folding to function: complex macromolecular reactions unraveled one-by-one with optical tweezers
PO Heidarsson, C Cecconi
Essays in Biochemistry 65 (1), 129-142, 2021
92021
Conformational dynamics of single protein molecules studied by direct mechanical manipulation.
PO Heidarsson, MM Naqvi, P Sonar, I Valpapuram, C Cecconi
Advances in protein chemistry and structural biology 92, 93-133, 2013
82013
PED in 2024: improving the community deposition of structural ensembles for intrinsically disordered proteins
H Ghafouri, T Lazar, A Del Conte, LG Tenorio Ku, P Tompa, SCE Tosatto, ...
Nucleic acids research 52 (D1), D536-D544, 2024
72024
The complex conformational dynamics of neuronal calcium sensor-1: a single molecule perspective
D Choudhary, BB Kragelund, PO Heidarsson, C Cecconi
Frontiers in molecular neuroscience 11, 468, 2018
72018
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