| Clinical pharmacokinetics and pharmacodynamics of clopidogrel XL Jiang, S Samant, LJ Lesko, S Schmidt Clinical pharmacokinetics 54 (2), 147-166, 2015 | 204 | 2015 |
| Psychedelic 5-methoxy-N, N-dimethyltryptamine: metabolism, pharmacokinetics, drug interactions, and pharmacological actions HW Shen, XL Jiang, J C Winter, AM Yu Current drug metabolism 11 (8), 659-666, 2010 | 189 | 2010 |
| High performance liquid chromatographic–mass spectrometric determination of ginsenoside Rg3 and its metabolites in rat plasma using solid-phase extraction for pharmacokinetic … HT Xie, GJ Wang, JG Sun, I Tucker, XC Zhao, YY Xie, H Li, X Jiang, ... Journal of Chromatography B 818 (2), 167-173, 2005 | 149 | 2005 |
| FDA approval summary: atezolizumab plus bevacizumab for the treatment of patients with advanced unresectable or metastatic hepatocellular carcinoma SJ Casak, M Donoghue, L Fashoyin-Aje, X Jiang, L Rodriguez, YL Shen, ... Clinical Cancer Research 27 (7), 1836-1841, 2021 | 128 | 2021 |
| Application of physiologically based pharmacokinetic modeling to predict acetaminophen metabolism and pharmacokinetics in children XL Jiang, P Zhao, JS Barrett, LJ Lesko, S Schmidt CPT: pharmacometrics & systems pharmacology 2 (10), 1-9, 2013 | 120 | 2013 |
| FDA approval summary: alpelisib plus fulvestrant for patients with HR-positive, HER2-negative, PIK3CA-mutated, advanced or metastatic breast cancer P Narayan, TM Prowell, JJ Gao, LL Fernandes, E Li, X Jiang, J Qiu, J Fan, ... Clinical Cancer Research 27 (7), 1842-1849, 2021 | 105 | 2021 |
| Pinoline may be used as a probe for CYP2D6 activity XL Jiang, HW Shen, AM Yu Drug Metabolism and Disposition 37 (3), 443-446, 2009 | 71 | 2009 |
| Determination of ginsenoside Rd in dog plasma by liquid chromatography–mass spectrometry after solid-phase extraction and its application in dog pharmacokinetics studies W Wang, GJ Wang, HT Xie, JG Sun, S Zhao, X Jiang, H Li, H Lv, MJ Xu, ... Journal of Chromatography B 852 (1-2), 8-14, 2007 | 58 | 2007 |
| Effects of CYP2D6 status on harmaline metabolism, pharmacokinetics and pharmacodynamics, and a pharmacogenetics-based pharmacokinetic model C Wu, XL Jiang, HW Shen, AM Yu Biochemical pharmacology 78 (6), 617-624, 2009 | 51 | 2009 |
| Uptake and metabolism of ginsenoside Rh2 and its aglycon protopanaxadiol by Caco-2 cells HT Xie, GJ Wang, M Chen, X Jiang, H Li, H Lv, CR Huang, R Wang, ... Biological and Pharmaceutical Bulletin 28 (2), 383-386, 2005 | 43 | 2005 |
| Development of a target cell-biologics-effector cell (TBE) complex-based cell killing model to characterize target cell depletion by T cell redirecting bispecific agents X Jiang, X Chen, TJ Carpenter, J Wang, R Zhou, HM Davis, DL Heald, ... MAbs 10 (6), 876-889, 2018 | 42 | 2018 |
| Effects of monoamine oxidase inhibitor and cytochrome P450 2D6 status on 5-methoxy-N, N-dimethyltryptamine metabolism and pharmacokinetics HW Shen, C Wu, XL Jiang, AM Yu Biochemical pharmacology 80 (1), 122-128, 2010 | 42 | 2010 |
| Drug-metabolizing enzyme, transporter, and nuclear receptor genetically modified mouse models XL Jiang, FJ Gonzalez, AM Yu Drug metabolism reviews 43 (1), 27-40, 2011 | 40 | 2011 |
| Development of a HPLC-MS assay for ginsenoside Rh2, a new anti-tumor substance from natural product and its pharacokinetic study in dogs HT Xie, GJ Wang, H Lv, RWJG Sun, XL Jiang, H Li, W Wang, CR Huang, ... European journal of drug metabolism and pharmacokinetics 30, 63-67, 2005 | 34 | 2005 |
| Minimal physiologically-based pharmacokinetic (mPBPK) model for a monoclonal antibody against interleukin-6 in mice with collagen-induced arthritis X Chen, X Jiang, WJ Jusko, H Zhou, W Wang Journal of pharmacokinetics and pharmacodynamics 43, 291-304, 2016 | 33 | 2016 |
| Development of a physiologically based pharmacokinetic model to predict disease-mediated therapeutic protein–drug interactions: modulation of multiple cytochrome P450 enzymes … X Jiang, Y Zhuang, Z Xu, W Wang, H Zhou The AAPS journal 18, 767-776, 2016 | 33 | 2016 |
| Development of a physiology-directed population pharmacokinetic and pharmacodynamic model for characterizing the impact of genetic and demographic factors on clopidogrel … XL Jiang, S Samant, JP Lewis, RB Horenstein, AR Shuldiner, ... European Journal of Pharmaceutical Sciences 82, 64-78, 2016 | 31 | 2016 |
| Humanized transgenic mouse models for drug metabolism and pharmacokinetic research HW Shen, XL Jiang, F J Gonzalez, AM Yu Current drug metabolism 12 (10), 997-1006, 2011 | 31 | 2011 |
| Nonlinear pharmacokinetics of 5-methoxy-N, N-dimethyltryptamine in mice HW Shen, XL Jiang, AM Yu Drug Metabolism and Disposition 39 (7), 1227-1234, 2011 | 29 | 2011 |
| Quantitation of human cytochrome P450 2D6 protein with immunoblot and mass spectrometry analysis AM Yu, J Qu, MA Felmlee, J Cao, XL Jiang Drug metabolism and disposition 37 (1), 170-177, 2009 | 29 | 2009 |
Hongwu ShenU.S. Food and Drug AdministrationVerified email at fda.hhs.gov
