Ruiwen Zhang

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Jiang-Jiang QinProfessor, HIM, Chinese Academy of SciencesVerified email at ucas.ac.cn
Robert B. DiasioMayo Clinic Cancer CenterVerified email at mayo.edu
Subhasree NagTexas Tech University Health Sciences Center, Pacific Northwest National LaboratoryVerified email at ttuhsc.edu
sukesh vorugantiUT Southwestern Medical Center (Sr. Research Associate)Verified email at ttuhsc.edu
Qiuyin CaiVanderbilt University Medical CenterVerified email at vanderbilt.edu
Van Meir, Erwin G.Professor of Neurosurgery and Hematology & Medical Oncology, Emory UniversityVerified email at emory.edu
Gautam PrasadGoogleVerified email at google.com
Horrick SharmaSWOSUVerified email at swosu.edu
Sharad SharmaPrincipal Scientist, Boehringer IngelheimVerified email at boehringer-ingelheim.com
SUSHANTA SARKARAppalachian College of PharmacyVerified email at students.acp.edu
Snehal Padhye Ph.D. MBACharles River LaboratoriesVerified email at crl.com
Oluf Dimitri RøeMD PhD NTNU, NorwayVerified email at ntnu.no
T.-C. HeMolecular Oncology Laboratory, The University of Chicago Medical CenterVerified email at bsd.uchicago.edu
Stephen BarnesUniversity of Alabama at BirminghamVerified email at uab.edu
Xiaolin ZiProfessor of Urology, Pharmacology and Pharmaceutical SciencesVerified email at uci.edu
Feng WangThe Chinese University of Hong KongVerified email at cuhk.edu.hk
Evrim GurpinarCancer Research UK Beatson InstituteVerified email at beatson.gla.ac.uk
Giampaolo TortoraMedical Oncology- Fondazione Policlinico Universitario Gemelli-IRCCS RomaVerified email at policlinicogemelli.it
Veronika KozlovskayaThe University of Alabama at BirminghamVerified email at uab.edu
Eugenia KharlampievaProfessor of Polymer Chemistry at Univ. of Alabama at BirminghamVerified email at uab.edu

Ruiwen Zhang

Professor of Pharmacology and Toxicology, Robert L. Boblitt Endowed Professor in Drug Discovery

Verified email at central.uh.edu

cancer pharmacology pharmaceutical sciences


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Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: population characteristics, newly identified deficient patients, and clinical … Z Lu, R Zhang, RB Diasio Cancer research 53 (22), 5433-5438, 1993	485	1993
The MDM2-p53 pathway revisited S Nag, J Qin, KS Srivenugopal, M Wang, R Zhang Journal of biomedical research 27 (4), 254, 2013	421	2013
Experimental therapy of hepatoma with artemisinin and its derivatives: in vitro and in vivo activity, chemosensitization, and mechanisms of action J Hou, D Wang, R Zhang, H Wang Clinical cancer research 14 (17), 5519-5530, 2008	412	2008
In vitro anti-cancer activity and structure–activity relationships of natural products isolated from fruits of Panax ginseng W Wang, Y Zhao, ER Rayburn, DL Hill, H Wang, R Zhang Cancer chemotherapy and pharmacology 59, 589-601, 2007	395	2007
Anti-inflammatory agents for cancer therapy ER Rayburn, SJ Ezell, R Zhang Molecular and cellular pharmacology 1 (1), 29, 2009	394	2009
Method of down-regulating gene expression S Agrawal, RB Diasio, R Zhang US Patent 5,591,721, 1997	366*	1997
Curcumin, a dietary component, has anticancer, chemosensitization, and radiosensitization effects by down-regulating the MDM2 oncogene through the PI3K/mTOR/ETS2 pathway M Li, Z Zhang, DL Hill, H Wang, R Zhang Cancer research 67 (5), 1988-1996, 2007	362	2007
Ginsenosides as Anticancer Agents: In vitro and in vivo Activities, Structure–Activity Relationships, and Molecular Mechanisms of Action SA Nag, JJ Qin, W Wang, MH Wang, H Wang, R Zhang Frontiers in pharmacology 3, 25, 2012	352	2012
Wnt/β-catenin signaling pathway as novel cancer drug targets HH Luu, R Zhang, RC Haydon, E Rayburn, Q Kang, W Si, JK Park, ... Current cancer drug targets 4 (8), 653-671, 2004	351	2004
Mixed-backbone oligonucleotides as second generation antisense oligonucleotides: In vitro and in vivo studies S Agrawal, Z Jiang, Q Zhao, D Shaw, Q Cai, A Roskey, L Channavajjala, ... Proceedings of the National Academy of Sciences 94 (6), 2620-2625, 1997	343	1997
MDM2 and human malignancies: expression, clinical pathology, prognostic markers, and implications for chemotherapy E Rayburn, R Zhang, J He, H Wang Current cancer drug targets 5 (1), 27-41, 2005	331	2005
Ribosomal protein S7 as a novel modulator of p53–MDM2 interaction: binding to MDM2, stabilization of p53 protein, and activation of p53 function D Chen, Z Zhang, M Li, W Wang, Y Li, ER Rayburn, DL Hill, H Wang, ... Oncogene 26 (35), 5029-5037, 2007	314	2007
MDM2 is a negative regulator of p21WAF1/CIP1, independent of p53 Z Zhang, H Wang, M Li, S Agrawal, X Chen, R Zhang Journal of Biological Chemistry 279 (16), 16000-16006, 2004	299	2004
Dietary flavonoids, quercetin, luteolin and genistein, reduce oxidative DNA damage and lipid peroxidation and quench free radicals Q Cai, RO Rahn, R Zhang Cancer letters 119 (1), 99-107, 1997	288	1997
Antisense therapy targeting MDM2 oncogene in prostate cancer: Effects on proliferation, apoptosis, multiple gene expression, and chemotherapy Z Zhang, M Li, H Wang, S Agrawal, R Zhang Proceedings of the National Academy of Sciences 100 (20), 11636-11641, 2003	261	2003
Dihydroartemisinin induces apoptosis and sensitizes human ovarian cancer cells to carboplatin therapy T Chen, M Li, R Zhang, H Wang Journal of cellular and molecular medicine 13 (7), 1358-1370, 2009	254	2009
Synergistic activation of p53 by inhibition of MDM2 expression and DNA damage L Chen, S Agrawal, W Zhou, R Zhang, J Chen Proceedings of the National Academy of Sciences 95 (1), 195-200, 1998	251	1998
Antisense, RNAi, and gene silencing strategies for therapy: mission possible or impossible? ER Rayburn, R Zhang Drug discovery today 13 (11-12), 513-521, 2008	245	2008
Targeting the NFκB signaling pathways for breast cancer prevention and therapy W Wang, SA Nag, R Zhang Current medicinal chemistry 22 (2), 264-289, 2015	232	2015
Quercetin-nanostructured lipid carriers: Characteristics and anti-breast cancer activities in vitro M Sun, S Nie, X Pan, R Zhang, Z Fan, S Wang Colloids and Surfaces B: Biointerfaces 113, 15-24, 2014	232	2014

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