Brenton Hoffman
Brenton Hoffman
James L and Elizabeth M. Vincent Associate Professor of Biomedical Engineering, Duke University
Verified email at - Homepage
Cited by
Cited by
Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics
C Grashoff, BD Hoffman, MD Brenner, R Zhou, M Parsons, MT Yang, ...
Nature 466 (7303), 263-266, 2010
Dynamic molecular processes mediate cellular mechanotransduction
BD Hoffman, C Grashoff, MA Schwartz
Nature 475 (7356), 316-323, 2011
Microrheology, stress fluctuations, and active behavior of living cells
AWC Lau, BD Hoffman, A Davies, JC Crocker, TC Lubensky
Physical review letters 91 (19), 198101, 2003
The consensus mechanics of cultured mammalian cells
BD Hoffman, G Massiera, KM Van Citters, JC Crocker
Proceedings of the National Academy of Sciences 103 (27), 10259-10264, 2006
Cell mechanics: dissecting the physical responses of cells to force
BD Hoffman, JC Crocker
Annual review of biomedical engineering 11, 259-288, 2009
Microrheology probes length scale dependent rheology
J Liu, ML Gardel, K Kroy, E Frey, BD Hoffman, JC Crocker, AR Bausch, ...
Physical review letters 96 (11), 118104, 2006
Multiple‐particle tracking and two‐point microrheology in cells
JC Crocker, BD Hoffman
Methods in cell biology 83, 141-178, 2007
Tension-sensitive actin assembly supports contractility at the epithelial zonula adherens
JM Leerberg, GA Gomez, S Verma, EJ Moussa, SK Wu, R Priya, ...
Current Biology 24 (15), 1689-1699, 2014
Discovery and characterization of small molecules that target the GTPase Ral
C Yan, D Liu, L Li, MF Wempe, S Guin, M Khanna, J Meier, B Hoffman, ...
Nature 515 (7527), 443-447, 2014
Towards a dynamic understanding of cadherin-based mechanobiology
BD Hoffman
Trends in cell biology 25 (12), 803-814, 2015
The role of F-actin and myosin in epithelial cell rheology
KM Van Citters, BD Hoffman, G Massiera, JC Crocker
Biophysical journal 91 (10), 3946-3956, 2006
Enucleated cells reveal differential roles of the nucleus in cell migration, polarity, and mechanotransduction
DM Graham, T Andersen, L Sharek, G Uzer, K Rothenberg, BD Hoffman, ...
Journal of Cell Biology 217 (3), 895-914, 2018
The role of extracellular matrix elasticity and composition in regulating the nucleus pulposus cell phenotype in the intervertebral disc: a narrative review
PY Hwang, J Chen, L Jing, BD Hoffman, LA Setton
Journal of biomechanical engineering 136 (2), 021010, 2014
Vinculin force-sensitive dynamics at focal adhesions enable effective directed cell migration
KE Rothenberg, DW Scott, N Christoforou, BD Hoffman
Biophysical journal 114 (7), 1680-1694, 2018
Tunable molecular tension sensors reveal extension-based control of vinculin loading
AS LaCroix, AD Lynch, ME Berginski, BD Hoffman
Elife 7, e33927, 2018
Comprehensive endogenous tagging of basement membrane components reveals dynamic movement within the matrix scaffolding
DP Keeley, E Hastie, R Jayadev, LC Kelley, Q Chi, SG Payne, JL Jeger, ...
Developmental cell 54 (1), 60-74. e7, 2020
TRPV4-mediated calcium signaling in mesenchymal stem cells regulates aligned collagen matrix formation and vinculin tension
CL Gilchrist, HA Leddy, L Kaye, ND Case, KE Rothenberg, D Little, ...
Proceedings of the National Academy of Sciences 116 (6), 1992-1997, 2019
Construction, imaging, and analysis of FRET-based tension sensors in living cells
AS LaCroix, KE Rothenberg, ME Berginski, AN Urs, BD Hoffman
Methods in cell biology 125, 161-186, 2015
Controlling cell geometry affects the spatial distribution of load across vinculin
KE Rothenberg, SS Neibart, AS LaCroix, BD Hoffman
Cellular and Molecular Bioengineering 8, 364-382, 2015
Regulation of Rac1 translocation and activation by membrane domains and their boundaries
K Moissoglu, V Kiessling, C Wan, BD Hoffman, A Norambuena, LK Tamm, ...
Journal of cell science 127 (11), 2565-2576, 2014
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