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Kenneth Y. Tsai MD, PhD
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Genomic classification of cutaneous melanoma
R Akbani, KC Akdemir, BA Aksoy, M Albert, A Ally, SB Amin, H Arachchi, ...
Cell 161 (7), 1681-1696, 2015
26302015
p63 and p73 are required for p53-dependent apoptosis in response to DNA damage
ER Flores, KY Tsai, D Crowley, S Sengupta, A Yang, F McKeon, T Jacks
Nature 416 (6880), 560-564, 2002
10422002
Role for the p53 homologue p73 in E2F-1-induced apoptosis
M Irwin, MC Marin, AC Phillips, RS Seelan, DI Smith, W Liu, ER Flores, ...
Nature 407 (6804), 645-648, 2000
7812000
Mutational landscape of aggressive cutaneous squamous cell carcinoma
CR Pickering, JH Zhou, JJ Lee, JA Drummond, SA Peng, RE Saade, ...
Clinical cancer research 20 (24), 6582-6592, 2014
6552014
Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos
KY Tsai, Y Hu, KF Macleod, D Crowley, L Yamasaki, T Jacks
Molecular cell 2 (3), 293-304, 1998
4601998
An intact HDM2 RING-finger domain is required for nuclear exclusion of p53
SD Boyd, KY Tsai, T Jacks
Nature cell biology 2 (9), 563-568, 2000
4512000
Safety and activity of lenalidomide and rituximab in untreated indolent lymphoma: an open-label, phase 2 trial
NH Fowler, RE Davis, S Rawal, L Nastoupil, FB Hagemeister, ...
The Lancet Oncology 15 (12), 1311-1318, 2014
2872014
Analysis of cell mechanics in single vinculin-deficient cells using a magnetic tweezer
FJ Alenghat, B Fabry, KY Tsai, WH Goldmann, DE Ingber
Biochemical and biophysical research communications 277 (1), 93-99, 2000
2872000
TAp63 prevents premature aging by promoting adult stem cell maintenance
X Su, M Paris, YJ Gi, KY Tsai, MS Cho, YL Lin, JA Biernaskie, S Sinha, ...
Cell stem cell 5 (1), 64-75, 2009
2862009
Genomic, pathway network, and immunologic features distinguishing squamous carcinomas
JD Campbell, C Yau, R Bowlby, Y Liu, K Brennan, H Fan, AM Taylor, ...
Cell reports 23 (1), 194-212. e6, 2018
2832018
Roles of the immune system in skin cancer
S Rangwala, KY Tsai
British Journal of Dermatology 165 (5), 953-965, 2011
2162011
The RAC1 P29S hotspot mutation in melanoma confers resistance to pharmacological inhibition of RAF
IR Watson, L Li, PK Cabeceiras, M Mahdavi, T Gutschner, G Genovese, ...
Cancer research 74 (17), 4845-4852, 2014
1802014
Comparative electrotonic analysis of three classes of rat hippocampal neurons
NT Carnevale, KY Tsai, BJ Claiborne, TH Brown
Journal of neurophysiology 78 (2), 703-720, 1997
1491997
The genomic landscape of Merkel cell carcinoma and clinicogenomic biomarkers of response to immune checkpoint inhibitor therapy
TC Knepper, M Montesion, JS Russell, ES Sokol, GM Frampton, VA Miller, ...
Clinical Cancer Research 25 (19), 5961-5971, 2019
1372019
Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates
V Chitsazzadeh, C Coarfa, JA Drummond, T Nguyen, A Joseph, ...
Nature communications 7 (1), 12601, 2016
1342016
IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo
A Venkatanarayan, P Raulji, W Norton, D Chakravarti, C Coarfa, X Su, ...
Nature 517 (7536), 626-630, 2015
1322015
TAp63 is a master transcriptional regulator of lipid and glucose metabolism
X Su, YJ Gi, D Chakravarti, IL Chan, A Zhang, X Xia, KY Tsai, ER Flores
Cell metabolism 16 (4), 511-525, 2012
1282012
Extracellular matrix and pulmonary hypertension: control of vascular smooth muscle cell contractility
KM Lee, KY Tsai, N Wang, DE Ingber
American Journal of Physiology-Heart and Circulatory Physiology 274 (1), H76-H82, 1998
1171998
Expression of cyclins E1 and E2 during mouse development and in neoplasia
Y Geng, Q Yu, W Whoriskey, F Dick, KY Tsai, HL Ford, DK Biswas, ...
Proceedings of the National Academy of Sciences 98 (23), 13138-13143, 2001
1102001
APOBEC mutation drives early-onset squamous cell carcinomas in recessive dystrophic epidermolysis bullosa
RJ Cho, LB Alexandrov, NY Den Breems, VS Atanasova, M Farshchian, ...
Science Translational Medicine 10 (455), eaas9668, 2018
1042018
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