Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1 CM Karsten, MK Pandey, J Figge, R Kilchenstein, PR Taylor, M Rosas, ... Nature medicine 18 (9), 1401-1406, 2012 | 487 | 2012 |
TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE M Ehlers, H Fukuyama, TL McGaha, A Aderem, JV Ravetch The Journal of experimental medicine 203 (3), 553-561, 2006 | 414 | 2006 |
Lymphocyte circadian clocks control lymph node trafficking and adaptive immune responses D Druzd, O Matveeva, L Ince, U Harrison, W He, C Schmal, H Herzel, ... Immunity 46 (1), 120-132, 2017 | 404 | 2017 |
Selective blockade of inhibitory Fcγ receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells KM Dhodapkar, JL Kaufman, M Ehlers, DK Banerjee, E Bonvini, S Koenig, ... Proceedings of the National Academy of Sciences 102 (8), 2910-2915, 2005 | 362 | 2005 |
The function of the soluble interleukin 6 (IL-6) receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half … M Peters, S Jacobs, M Ehlers, P Vollmer, J Müllberg, E Wolf, G Brem, ... The Journal of experimental medicine 183 (4), 1399-1406, 1996 | 333 | 1996 |
Toll‐like receptors in autoimmunity M Fischer, M Ehlers Annals of the New York Academy of Sciences 1143 (1), 21-34, 2008 | 165 | 2008 |
T cell–independent B cell activation induces immunosuppressive sialylated IgG antibodies C Hess, A Winkler, AK Lorenz, V Holecska, V Blanchard, S Eiglmeier, ... The Journal of clinical investigation 123 (9), 3788-3796, 2013 | 151 | 2013 |
Runx3 regulates integrin αE/CD103 and CD4 expression during development of CD4−/CD8+ T cells B Grueter, M Petter, T Egawa, K Laule-Kilian, CJ Aldrian, A Wuerch, ... The Journal of Immunology 175 (3), 1694-1705, 2005 | 144 | 2005 |
Tolerance induction with T cell–dependent protein antigens induces regulatory sialylated IgGs CM Oefner, A Winkler, C Hess, AK Lorenz, V Holecska, M Huxdorf, ... Journal of Allergy and Clinical Immunology 129 (6), 1647-1655. e13, 2012 | 131 | 2012 |
Identification of two novel regions of human IL-6 responsible for receptor binding and signal transduction. M Ehlers, J Grötzinger, FD DeHon, J Müllberg, JP Brakenhoff, J Liu, ... Journal of immunology (Baltimore, Md.: 1950) 153 (4), 1744-1753, 1994 | 131 | 1994 |
Opposing effects of Toll-like receptor stimulation induce autoimmunity or tolerance M Ehlers, JV Ravetch Trends in immunology 28 (2), 74-79, 2007 | 129 | 2007 |
Development of self-reactive germinal center B cells and plasma cells in autoimmune FcγRIIB-deficient mice T Tiller, J Kofer, C Kreschel, CE Busse, S Riebel, S Wickert, F Oden, ... Journal of Experimental Medicine 207 (12), 2767-2778, 2010 | 117 | 2010 |
Pathogenetic and clinical aspects of anti-neutrophil cytoplasmic autoantibody-associated vasculitides P Lamprecht, A Kerstein, S Klapa, S Schinke, CM Karsten, X Yu, M Ehlers, ... Frontiers in immunology 9, 680, 2018 | 105 | 2018 |
The transcription factor Zbtb7b promotes CD4 expression by antagonizing Runx-mediated activation of the CD4 silencer KF Wildt, G Sun, B Grueter, M Fischer, M Zamisch, M Ehlers, R Bosselut The Journal of Immunology 179 (7), 4405-4414, 2007 | 100 | 2007 |
Potential of murine IgG1 and human IgG4 to inhibit the classical complement and Fcγ receptor activation pathways GM Lilienthal, J Rahmöller, J Petry, YC Bartsch, A Leliavski, M Ehlers Frontiers in immunology 9, 357875, 2018 | 95 | 2018 |
The carbohydrate switch between pathogenic and immunosuppressive antigen‐specific antibodies M Collin, M Ehlers Experimental dermatology 22 (8), 511-514, 2013 | 94 | 2013 |
The transcription factor Ets1 is important for CD4 repression and Runx3 up-regulation during CD8 T cell differentiation in the thymus M Zamisch, L Tian, R Grenningloh, Y Xiong, KF Wildt, M Ehlers, IC Ho, ... Journal of Experimental Medicine 206 (12), 2685-2699, 2009 | 82 | 2009 |
Anti-GP2 IgA autoantibodies are associated with poor survival and cholangiocarcinoma in primary sclerosing cholangitis ST Jendrek, D Gotthardt, T Nitzsche, L Widmann, T Korf, MA Michaels, ... Gut 66 (1), 137-144, 2017 | 74 | 2017 |
IgG1 protects against renal disease in a mouse model of cryoglobulinaemia RT Strait, MT Posgai, A Mahler, N Barasa, CO Jacob, J Köhl, M Ehlers, ... Nature 517 (7535), 501-504, 2015 | 73 | 2015 |
Sialylated autoantigen-reactive IgG antibodies attenuate disease development in autoimmune mouse models of lupus nephritis and rheumatoid arthritis YC Bartsch, J Rahmöller, MMM Mertes, S Eiglmeier, FKM Lorenz, ... Frontiers in immunology 9, 1183, 2018 | 71 | 2018 |