Mortality of emergency abdominal surgery in high-, middle-and low-income countries Journal of British Surgery 103 (8), 971-988, 2016 | 301 | 2016 |
Determinants of morbidity and mortality following emergency abdominal surgery in children in low-income and middle-income countries GS Collaborative BMJ global health 1 (4), e000091, 2016 | 82 | 2016 |
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy Journal of British Surgery 106 (2), e103-e112, 2019 | 75 | 2019 |
Kinetic identification of membrane transporters that assist P-glycoprotein-mediated transport of digoxin and loperamide through a confluent monolayer of MDCKII-hMDR1 cells P Acharya, MP O'Connor, JW Polli, A Ayrton, H Ellens, J Bentz Drug metabolism and disposition 36 (2), 452-460, 2008 | 67 | 2008 |
A role for protein phosphorylation in cytochrome P450 3A4 ubiquitin-dependent proteasomal degradation YQ Wang, M Liao, N Hoe, P Acharya, C Deng, AN Krutchinsky, ... Journal of biological chemistry 284 (9), 5671-5684, 2009 | 61 | 2009 |
Ubiquitin-dependent proteasomal degradation of human liver cytochrome P450 2E1: identification of sites targeted for phosphorylation and ubiquitination YQ Wang, S Guan, P Acharya, DR Koop, Y Liu, M Liao, AL Burlingame, ... Journal of biological chemistry 286 (11), 9443-9456, 2011 | 59 | 2011 |
Liver cytochrome P450 3A ubiquitination in vivo by gp78/autocrine motility factor receptor and C terminus of Hsp70-interacting protein (CHIP) E3 ubiquitin ligases … SM Kim, P Acharya, JC Engel, MA Correia Journal of biological chemistry 285 (46), 35866-35877, 2010 | 39 | 2010 |
Multisite phosphorylation of human liver cytochrome P450 3A4 enhances Its gp78-and CHIP-mediated ubiquitination: a pivotal role of its Ser-478 residue in the gp78-catalyzed … YQ Wang, S Guan, P Acharya, Y Liu, RK Thirumaran, R Brandman, ... Molecular & Cellular Proteomics 11 (2), 2012 | 37 | 2012 |
RETRACTION: Hepatic Heme-Regulated Inhibitor (HRI) Eukaryotic Initiation Factor 2α Kinase: A Protagonist of Heme-Mediated Translational Control of CYP2B Enzymes and a Modulator … P Acharya, JJ Chen, MA Correia Molecular pharmacology 77 (4), 575-592, 2010 | 36 | 2010 |
P-Glycoprotein (P-gp) Expressed in a Confluent Monolayer of hMDR1− MDCKII Cells Has More Than One Efflux Pathway with Cooperative Binding Sites P Acharya, TT Tran, JW Polli, A Ayrton, H Ellens, J Bentz Biochemistry 45 (51), 15505-15519, 2006 | 36 | 2006 |
RETRACTION: Hepatic CYP3A Suppression by High Concentrations of Proteasomal Inhibitors: A Consequence of Endoplasmic Reticulum (ER) Stress Induction, Activation of RNA … P Acharya, JC Engel, MA Correia Molecular pharmacology 76 (3), 503-515, 2009 | 31 | 2009 |
If the KI is defined by the free energy of binding to P-glycoprotein, which kinetic parameters define the IC50 for the Madin-Darby canine kidney II cell line overexpressing … AA Lumen, P Acharya, JW Polli, A Ayrton, H Ellens, J Bentz Drug metabolism and disposition 38 (2), 260-269, 2010 | 30 | 2010 |
Liver cytochrome P450 3A endoplasmic reticulum-associated degradation: a major role for the p97 AAA ATPase in cytochrome P450 3A extraction into the cytosol P Acharya, M Liao, JC Engel, MA Correia Journal of biological chemistry 286 (5), 3815-3828, 2011 | 26 | 2011 |
Fitting the elementary rate constants of the P-gp transporter network in the hMDR1-MDCK confluent cell monolayer using a particle swarm algorithm D Agnani, P Acharya, E Martinez, TT Tran, F Abraham, F Tobin, H Ellens, ... PLoS One 6 (10), e25086, 2011 | 21 | 2011 |
Hepatic CYP3A suppression by high concentrations of proteasomal inhibitors: A consequence of endoplasmic reticulum (ER) stress induction, activation of RNA-dependent protein … P Acharya, JC Engel, MA Correia MOLECULAR PHARMACOLOGY 100 (2), 82-82, 2021 | 1 | 2021 |
Kinetic analysis of cytochrome P450 19A1 P Acharya, M Liao, M Almira DRUG METABOLISM REVIEWS 41, 53-53, 2009 | 1 | 2009 |
For P‐glycoprotein mediated transport through a confluent cell monolayer, the IC50 of a P‐gp substrate depends inversely upon the passive permeability coefficient of the probe … P Acharya, J Bentz The FASEB Journal 21 (6), A1188-A1188, 2007 | 1 | 2007 |
Reactive episodes in borderline lepromatous leprosy--a case report. PV Acharya, OP Gupta, SP Nigam, RV Agrawal Leprosy in India 48 (3), 311-313, 1976 | 1 | 1976 |
Hepatic heme-regulated inhibitor (HRI) eukaryotic initiation factor 2 alpha kinase: a protagonist of heme-mediated translational control of CYP2B enzymes and a modulator of … P Acharya, JJ Chen, MA Correia MOLECULAR PHARMACOLOGY 100 (2), 65-65, 2021 | | 2021 |
Global variation in anastomosis and end colostomy formation following left-sided colorectal resection GlobalSurg Collaborative, ... BJS Open 3 (3), 403-414, 2019 | | 2019 |