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Chen-Hsiang Shen
Chen-Hsiang Shen
Vaccine Research Center, NIAID
Verified email at nih.gov
Title
Cited by
Cited by
Year
Vaccine-induced antibodies that neutralize group 1 and group 2 influenza A viruses
MG Joyce, AK Wheatley, PV Thomas, GY Chuang, C Soto, RT Bailer, ...
Cell 166 (3), 609-623, 2016
2482016
Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1
K Xu, P Acharya, R Kong, C Cheng, GY Chuang, K Liu, MK Louder, ...
doi: https://doi.org/10.1101/306282, 2018
2092018
Quantification of the impact of the HIV-1-glycan shield on antibody elicitation
T Zhou, NA Doria-Rose, C Cheng, GBE Stewart-Jones, GY Chuang, ...
Cell reports 19 (4), 719-732, 2017
1422017
Amprenavir complexes with HIV‐1 protease and its drug‐resistant mutants altering hydrophobic clusters
CH Shen, YF Wang, AY Kovalevsky, RW Harrison, IT Weber
The FEBS journal 277 (18), 3699-3714, 2010
1322010
HIV-1 protease with 20 mutations exhibits extreme resistance to clinical inhibitors through coordinated structural rearrangements
J Agniswamy, CH Shen, A Aniana, JM Sayer, JM Louis, IT Weber
Biochemistry 51 (13), 2819-2828, 2012
1002012
Antibody lineages with vaccine-induced antigen-binding hotspots develop broad HIV neutralization
R Kong, H Duan, Z Sheng, K Xu, P Acharya, X Chen, C Cheng, ...
Cell 178 (3), 567-584. e19, 2019
702019
PaRSnIP: sequence-based protein solubility prediction using gradient boosting machine
R Rawi, R Mall, K Kunji, CH Shen, PD Kwong, GY Chuang
Bioinformatics 34 (7), 1092-1098, 2018
662018
A neutralizing antibody recognizing primarily N-linked glycan targets the silent face of the HIV envelope
T Zhou, A Zheng, U Baxa, GY Chuang, IS Georgiev, R Kong, S O’Dell, ...
Immunity 48 (3), 500-513. e6, 2018
632018
Role of humoral immunity against hepatitis B virus core antigen in the pathogenesis of acute liver failure
Z Chen, G Diaz, T Pollicino, H Zhao, RE Engle, P Schuck, CH Shen, ...
Proceedings of the National Academy of Sciences 115 (48), E11369-E11378, 2018
542018
Structural survey of broadly neutralizing antibodies targeting the HIV-1 Env trimer delineates epitope categories and characteristics of recognition
GY Chuang, J Zhou, P Acharya, R Rawi, CH Shen, Z Sheng, B Zhang, ...
Structure 27 (1), 196-206. e6, 2019
532019
Longitudinal analysis reveals early development of three MPER-directed neutralizing antibody lineages from an HIV-1-infected individual
SJ Krebs, YD Kwon, CA Schramm, WH Law, G Donofrio, KH Zhou, S Gift, ...
Immunity 50 (3), 677-691. e13, 2019
502019
Long‐range electrostatics‐induced two‐proton transfer captured by neutron crystallography in an enzyme catalytic site
O Gerlits, T Wymore, A Das, CH Shen, JM Parks, JC Smith, KL Weiss, ...
Angewandte Chemie 128 (16), 5008-5011, 2016
482016
Extreme multidrug resistant HIV-1 protease with 20 mutations is resistant to novel protease inhibitors with P1′-pyrrolidinone or P2-tris-tetrahydrofuran
J Agniswamy, CH Shen, YF Wang, AK Ghosh, KV Rao, CX Xu, JM Sayer, ...
Journal of medicinal chemistry 56 (10), 4017-4027, 2013
402013
Novel P2 Tris-tetrahydrofuran Group in Antiviral Compound 1 (GRL-0519) Fills the S2 Binding Pocket of Selected Mutants of HIV-1 Protease
H Zhang, YF Wang, CH Shen, J Agniswamy, KV Rao, CX Xu, AK Ghosh, ...
Journal of medicinal chemistry 56 (3), 1074-1083, 2013
352013
Paired heavy-and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses
BB Banach, G Cerutti, AS Fahad, CH Shen, MO De Souza, PS Katsamba, ...
Cell reports 37 (1), 109771, 2021
322021
Structure of super-potent antibody CAP256-VRC26. 25 in complex with HIV-1 envelope reveals a combined mode of trimer-apex recognition
J Gorman, GY Chuang, YT Lai, CH Shen, JC Boyington, A Druz, H Geng, ...
Cell reports 31 (1), 107488, 2020
282020
Automated prediction of HIV drug resistance from genotype data
RWHITW ChenHsiang Shen, Xiaxia Yu
BMC Bioinformatics 17 (Suppl 8), 278, 2016
28*2016
Homocysteine, vitamin B6, and lipid in cardiovascular disease
SJ Chan, CN Chang, JC Hsu, YS Lee, CH Shen
Nutrition 18 (7-8), 595-598, 2002
262002
Conformational variation of an extreme drug resistant mutant of HIV protease
CH Shen, YC Chang, J Agniswamy, RW Harrison, IT Weber
Journal of Molecular Graphics and Modelling 62, 87-96, 2015
242015
Improvement of antibody functionality by structure-guided paratope engraftment
Q Liu, YT Lai, P Zhang, MK Louder, A Pegu, R Rawi, M Asokan, X Chen, ...
Nature communications 10 (1), 1-13, 2019
222019
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