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An interleukin-17–mediated paracrine network promotes tumor resistance to anti-angiogenic therapy AS Chung, X Wu, G Zhuang, H Ngu, I Kasman, J Zhang, JM Vernes, ... Nature medicine 19 (9), 1114-1123, 2013 | 484 | 2013 |
Changes in the synaptic proteome in tauopathy and rescue of tau-induced synapse loss by C1q antibodies B Dejanovic, MA Huntley, A De Mazière, WJ Meilandt, T Wu, K Srinivasan, ... Neuron 100 (6), 1322-1336. e7, 2018 | 372 | 2018 |
RIPK1 inhibits ZBP1-driven necroptosis during development K Newton, KE Wickliffe, A Maltzman, DL Dugger, A Strasser, VC Pham, ... Nature 540 (7631), 129-133, 2016 | 333 | 2016 |
Complement C3 is activated in human AD brain and is required for neurodegeneration in mouse models of amyloidosis and tauopathy T Wu, B Dejanovic, VD Gandham, A Gogineni, R Edmonds, S Schauer, ... Cell reports 28 (8), 2111-2123. e6, 2019 | 322 | 2019 |
Early postnatal astroglial cells produce multilineage precursors and neural stem cells in vivo YM Ganat, J Silbereis, C Cave, H Ngu, GM Anderson, Y Ohkubo, LR Ment, ... Journal of Neuroscience 26 (33), 8609-8621, 2006 | 284 | 2006 |
Mechanical properties of actin stress fibers in living cells L Lu, SJ Oswald, H Ngu, FCP Yin Biophysical journal 95 (12), 6060-6071, 2008 | 190 | 2008 |
Hepatitis C virus induces epidermal growth factor receptor activation via CD81 binding for viral internalization and entry J Diao, H Pantua, H Ngu, L Komuves, L Diehl, G Schaefer, SB Kapadia Journal of virology 86 (20), 10935-10949, 2012 | 163 | 2012 |
Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology SH Lee, WJ Meilandt, L Xie, VD Gandham, H Ngu, KH Barck, ... Neuron 109 (8), 1283-1301. e6, 2021 | 162 | 2021 |
Function of CSF1 and IL34 in macrophage homeostasis, inflammation, and cancer WY Lin, D Xu, CD Austin, P Caplazi, K Senger, Y Sun, S Jeet, J Young, ... Frontiers in immunology 10, 2019, 2019 | 148 | 2019 |
Trem2 deletion reduces late-stage amyloid plaque accumulation, elevates the Aβ42: Aβ40 ratio, and exacerbates axonal dystrophy and dendritic spine loss in the PS2APP Alzheimer … WJ Meilandt, H Ngu, A Gogineni, G Lalehzadeh, SH Lee, K Srinivasan, ... Journal of Neuroscience 40 (9), 1956-1974, 2020 | 132 | 2020 |
Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease CE Le Pichon, WJ Meilandt, S Dominguez, H Solanoy, H Lin, H Ngu, ... Science translational medicine 9 (403), eaag0394, 2017 | 132 | 2017 |
Antibody-mediated targeting of tau in vivo does not require effector function and microglial engagement SH Lee, CE Le Pichon, O Adolfsson, V Gafner, M Pihlgren, H Lin, ... Cell reports 16 (6), 1690-1700, 2016 | 118 | 2016 |
Differential drug class‐specific metastatic effects following treatment with a panel of angiogenesis inhibitors AS Chung, M Kowanetz, X Wu, G Zhuang, H Ngu, D Finkle, L Komuves, ... The Journal of pathology 227 (4), 404-416, 2012 | 97 | 2012 |
Ubiquitin ligase COP1 suppresses neuroinflammation by degrading c/EBPβ in microglia A Ndoja, R Reja, SH Lee, JD Webster, H Ngu, CM Rose, DS Kirkpatrick, ... Cell 182 (5), 1156-1169. e12, 2020 | 93 | 2020 |
Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors M Merchant, J Moffat, G Schaefer, J Chan, X Wang, C Orr, J Cheng, ... PloS one 12 (10), e0185862, 2017 | 93 | 2017 |
Enhancing the antitumor efficacy of a cell-surface death ligand by covalent membrane display PM Nair, H Flores, A Gogineni, S Marsters, DA Lawrence, RF Kelley, ... Proceedings of the National Academy of Sciences 112 (18), 5679-5684, 2015 | 86 | 2015 |
Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration CD Pozniak, A Sengupta Ghosh, A Gogineni, JE Hanson, SH Lee, ... Journal of Experimental Medicine 210 (12), 2553-2567, 2013 | 83 | 2013 |
Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer’s disease mouse models B Dejanovic, T Wu, MC Tsai, D Graykowski, VD Gandham, CM Rose, ... Nature Aging 2 (9), 837-850, 2022 | 80 | 2022 |
Multiple sclerosis risk gene Mertk is required for microglial activation and subsequent remyelination K Shen, M Reichelt, RV Kyauk, H Ngu, YAA Shen, O Foreman, ... Cell Reports 34 (10), 2021 | 79 | 2021 |