Pablo Sobrado
Pablo Sobrado
Professor, Department of Biochemistry, Virginia Tech
Verified email at - Homepage
Cited by
Cited by
X-ray structure of a mammalian stearoyl-CoA desaturase
Y Bai, JG McCoy, EJ Levin, P Sobrado, KR Rajashankar, BG Fox, M Zhou
Nature 524 (7564), 252-256, 2015
A rapid and high content assay that measures cyto-ID-stained autophagic compartments and estimates autophagy flux with potential clinical applications
S Guo, Y Liang, SF Murphy, A Huang, H Shen, DF Kelly, P Sobrado, ...
Autophagy 11 (3), 560-572, 2015
Aspergillus fumigatus SidA Is a Highly Specific Ornithine Hydroxylase with Bound Flavin Cofactor
SW Chocklett, P Sobrado
Biochemistry 49 (31), 6777-6783, 2010
Structural insight into the mechanism of oxygen activation and substrate selectivity of flavin-dependent N-hydroxylating monooxygenases
S Franceschini, M Fedkenheuer, NJ Vogelaar, HH Robinson, P Sobrado, ...
Biochemistry 51 (36), 7043-7045, 2012
In planta variation of volatile biosynthesis: an alternative biosynthetic route to the formation of the pathogen-induced volatile homoterpene DMNT via triterpene degradation in …
R Sohrabi, JH Huh, S Badieyan, LH Rakotondraibe, DJ Kliebenstein, ...
The Plant Cell 27 (3), 874-890, 2015
gfsA encodes a novel galactofuranosyltransferase involved in biosynthesis of galactofuranose antigen of O‐glycan in A spergillus nidulans and A spergillus fumigatus
Y Komachi, S Hatakeyama, H Motomatsu, T Futagami, K Kizjakina, ...
Molecular microbiology 90 (5), 1054-1073, 2013
Structure, mechanism, and dynamics of UDP-galactopyranose mutase
JJ Tanner, L Boechi, JA McCammon, P Sobrado
Archives of biochemistry and biophysics 544, 128-141, 2014
Solvent and Primary Deuterium Isotope Effects Show That Lactate CH and OH Bond Cleavages Are Concerted in Y254F Flavocytochrome b2, Consistent with a …
P Sobrado, PF Fitzpatrick
Biochemistry 42 (51), 15208-15214, 2003
Chemical mechanism of UDP-galactopyranose mutase from Trypanosoma cruzi: a potential drug target against Chagas' disease
M Oppenheimer, AL Valenciano, K Kizjakina, J Qi, P Sobrado
PloS one 7 (3), e32918, 2012
Characterization of recombinant UDP-galactopyranose mutase from Aspergillus fumigatus
M Oppenheimer, MB Poulin, TL Lowary, RF Helm, P Sobrado
Archives of Biochemistry and Biophysics 502 (1), 31-38, 2010
Biosynthesis of galactofuranose in kinetoplastids: novel therapeutic targets for treating leishmaniasis and chagas' disease
M Oppenheimer, AL Valenciano, P Sobrado
Enzyme research 2011, 2011
An unprecedented NADPH domain conformation in lysine monooxygenase NbtG provides insights into uncoupling of oxygen consumption from substrate hydroxylation
C Binda, RM Robinson, JSM Del Campo, ND Keul, PJ Rodriguez, ...
Journal of Biological Chemistry 290 (20), 12676-12688, 2015
Dual role of NADP (H) in the reaction of a flavin dependent N-hydroxylating monooxygenase
E Romero, M Fedkenheuer, SW Chocklett, J Qi, M Oppenheimer, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1824 (6), 850-857, 2012
Crystal structures and small-angle X-ray scattering analysis of UDP-galactopyranose mutase from the pathogenic fungus Aspergillus fumigatus
R Dhatwalia, H Singh, M Oppenheimer, DB Karr, JC Nix, P Sobrado, ...
Journal of Biological Chemistry 287 (12), 9041-9051, 2012
Kinetic solvent viscosity effects as probes for studying the mechanisms of enzyme action
G Gadda, P Sobrado
Biochemistry 57 (25), 3445-3453, 2018
Sinorhizobium meliloti Chemotaxis to Multiple Amino Acids Is Mediated by the Chemoreceptor McpU
BA Webb, KK Compton, JSM Del Campo, D Taylor, P Sobrado, BE Scharf
Molecular Plant-Microbe Interactions 30 (10), 770-777, 2017
The structure of the antibiotic deactivating, N-hydroxylating rifampicin monooxygenase
LK Liu, H Abdelwahab, JSM Del Campo, R Mehra-Chaudhary, P Sobrado, ...
Journal of Biological Chemistry 291 (41), 21553-21562, 2016
Probing the relative timing of hydrogen abstraction steps in the flavocytochrome b 2 reaction with primary and solvent deuterium isotope effects and mutant enzymes
P Sobrado, SC Daubner, PF Fitzpatrick
Biochemistry 40 (4), 994-1001, 2001
C4a-Hydroperoxyflavin Formation in N-Hydroxylating Flavin Monooxygenases Is Mediated by the 2′-OH of the Nicotinamide Ribose of NADP+
R Robinson, S Badieyan, P Sobrado
Biochemistry 52 (51), 9089-9091, 2013
Identification of the binding region of the [2Fe-2S] ferredoxin in stearoyl-acyl carrier protein desaturase: insight into the catalytic complex and mechanism of action
P Sobrado, KS Lyle, SP Kaul, MM Turco, I Arabshahi, A Marwah, BG Fox
Biochemistry 45 (15), 4848-4858, 2006
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