Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma BA Walker, K Mavrommatis, CP Wardell, TC Ashby, M Bauer, FE Davies, ... Blood, The Journal of the American Society of Hematology 132 (6), 587-597, 2018 | 432 | 2018 |
A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis BA Walker, K Mavrommatis, CP Wardell, TC Ashby, M Bauer, F Davies, ... Leukemia 33 (1), 159-170, 2019 | 431 | 2019 |
Genetic variants synthesize to produce paneth cell phenotypes that define subtypes of Crohn's disease KL VanDussen, TC Liu, D Li, F Towfic, N Modiano, R Winter, ... Gastroenterology 146 (1), 200-209, 2014 | 217 | 2014 |
Iberdomide (CC-220) is a potent cereblon E3 ligase modulator with antitumor and immunostimulatory activities in lenalidomide-and pomalidomide-resistant multiple myeloma cells … CC Bjorklund, J Kang, M Amatangelo, A Polonskaia, M Katz, H Chiu, ... Leukemia 34 (4), 1197-1201, 2020 | 165 | 2020 |
Genome-wide siRNA screen for mediators of NF-κB activation BE Gewurz, F Towfic, JC Mar, NP Shinners, K Takasaki, B Zhao, ... Proceedings of the National Academy of Sciences 109 (7), 2467-2472, 2012 | 133 | 2012 |
Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse JA Carrero, B Calderon, F Towfic, MN Artyomov, ER Unanue PloS one 8 (3), e59701, 2013 | 131 | 2013 |
Multiple cereblon genetic changes are associated with acquired resistance to lenalidomide or pomalidomide in multiple myeloma S Gooding, N Ansari-Pour, F Towfic, M Ortiz Estévez, PP Chamberlain, ... Blood, The Journal of the American Society of Hematology 137 (2), 232-237, 2021 | 129 | 2021 |
Laquinimod arrests experimental autoimmune encephalomyelitis by activating the aryl hydrocarbon receptor J Kaye, V Piryatinsky, T Birnberg, T Hingaly, E Raymond, R Kashi, ... Proceedings of the National Academy of Sciences 113 (41), E6145-E6152, 2016 | 127 | 2016 |
Pridopidine activates neuroprotective pathways impaired in Huntington Disease M Geva, R Kusko, H Soares, KD Fowler, T Birnberg, S Barash, ... Human molecular genetics 25 (18), 3975-3987, 2016 | 107 | 2016 |
High subclonal fraction of 17p deletion is associated with poor prognosis in multiple myeloma A Thakurta, M Ortiz, P Blecua, F Towfic, J Corre, NV Serbina, E Flynt, Z Yu, ... Blood, The Journal of the American Society of Hematology 133 (11), 1217-1221, 2019 | 103 | 2019 |
Protein-RNA interface residue prediction using machine learning: an assessment of the state of the art RR Walia, C Caragea, BA Lewis, F Towfic, M Terribilini, Y El-Manzalawy, ... BMC bioinformatics 13, 1-20, 2012 | 97 | 2012 |
Prognosis, Biology, and Targeting of TP53 Dysregulation in Multiple Myeloma E Flynt, K Bisht, V Sridharan, M Ortiz, F Towfic, A Thakurta Cells 9 (2), 287, 2020 | 77 | 2020 |
Struct-NB: predicting protein-RNA binding sites using structural features F Towfic, C Caragea, DC Gemperline, D Dobbs, V Honavar International journal of data mining and bioinformatics 4 (1), 21-43, 2010 | 53 | 2010 |
Comparing the biological impact of glatiramer acetate with the biological impact of a generic F Towfic, JM Funt, KD Fowler, S Bakshi, E Blaugrund, MN Artyomov, ... PloS one 9 (1), e83757, 2014 | 49 | 2014 |
Multiple Myeloma DREAM Challenge reveals epigenetic regulator PHF19 as marker of aggressive disease MJ Mason, C Schinke, CLP Eng, F Towfic, F Gruber, A Dervan, BS White, ... Leukemia 34 (7), 1866-1874, 2020 | 43 | 2020 |
A pharmacogenetic signature of high response to Copaxone in late-phase clinical-trial cohorts of multiple sclerosis CJ Ross, F Towfic, J Shankar, D Laifenfeld, M Thoma, M Davis, B Weiner, ... Genome medicine 9, 1-15, 2017 | 34 | 2017 |
Aligning biomolecular networks using modular graph kernels F Towfic, MHW Greenlee, V Honavar International Workshop on Algorithms in Bioinformatics, 345-361, 2009 | 34 | 2009 |
Detection of gene orthology from gene co-expression and protein interaction networks F Towfic, S VanderPIas, CA OIiver, OI Couture, CK TuggIe, ... BMC bioinformatics 11, 1-10, 2010 | 32 | 2010 |
Leveraging existing data sets to generate new insights into Alzheimer’s disease biology in specific patient subsets KD Fowler, JM Funt, MN Artyomov, B Zeskind, SE Kolitz, F Towfic Scientific reports 5 (1), 14324, 2015 | 29 | 2015 |
The location of the t(4;14) translocation breakpoint within the NSD2 gene identifies a subset of patients with high-risk NDMM N Stong, M Ortiz-Estévez, F Towfic, M Samur, A Agarwal, J Corre, E Flynt, ... Blood 141 (13), 1574-1583, 2023 | 23 | 2023 |