Genetics of rheumatoid arthritis contributes to biology and drug discovery Y Okada, D Wu, G Trynka, T Raj, C Terao, K Ikari, Y Kochi, K Ohmura, ... Nature 506 (7488), 376-381, 2014 | 2557 | 2014 |
New insights into the genetic etiology of Alzheimer’s disease and related dementias C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ... Nature genetics 54 (4), 412-436, 2022 | 1213 | 2022 |
Gene expression elucidates functional impact of polygenic risk for schizophrenia M Fromer, P Roussos, SK Sieberts, JS Johnson, DH Kavanagh, ... Nature neuroscience 19 (11), 1442-1453, 2016 | 1105 | 2016 |
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci PL De Jager, G Srivastava, K Lunnon, J Burgess, LC Schalkwyk, L Yu, ... Nature neuroscience 17 (9), 1156-1163, 2014 | 938 | 2014 |
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology N Mullins, AJ Forstner, KS O’Connell, B Coombes, JRI Coleman, Z Qiao, ... Nature genetics 53 (6), 817-829, 2021 | 931 | 2021 |
Progress and promise of genome-wide association studies for human complex trait genetics BE Stranger, EA Stahl, T Raj Genetics 187 (2), 367-383, 2011 | 767 | 2011 |
The transcriptional landscape of age in human peripheral blood MJ Peters, R Joehanes, LC Pilling, C Schurmann, KN Conneely, J Powell, ... Nature communications 6 (1), 1-14, 2015 | 629 | 2015 |
CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology EM Bradshaw, LB Chibnik, BT Keenan, L Ottoboni, T Raj, A Tang, ... Nature neuroscience 16 (7), 848-850, 2013 | 616 | 2013 |
Patterns of Cis Regulatory Variation in Diverse Human Populations BE Stranger, SB Montgomery, AS Dimas, L Parts, O Stegle, CE Ingle, ... PLoS genetics 8 (4), e1002639, 2012 | 579 | 2012 |
Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes T Raj, K Rothamel, S Mostafavi, C Ye, MN Lee, JM Replogle, T Feng, ... Science 344 (6183), 519-523, 2014 | 546 | 2014 |
Common genetic variants modulate pathogen-sensing responses in human dendritic cells MN Lee, C Ye, AC Villani, T Raj, W Li, TM Eisenhaure, SH Imboywa, ... Science 343 (6175), 1246980, 2014 | 491 | 2014 |
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4, and the risk of late-onset Alzheimer disease in African Americans C Reitz, G Jun, A Naj, R Rajbhandary, BN Vardarajan, LS Wang, ... Jama 309 (14), 1483-1492, 2013 | 477 | 2013 |
Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects NA Patsopoulos, LF Barcellos, RQ Hintzen, C Schaefer, CM Van Duijn, ... PLoS genetics 9 (11), e1003926, 2013 | 387 | 2013 |
Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer’s disease susceptibility T Raj, YI Li, G Wong, J Humphrey, M Wang, S Ramdhani, YC Wang, B Ng, ... Nature genetics 50 (11), 1584-1592, 2018 | 361 | 2018 |
A common haplotype lowers PU. 1 expression in myeloid cells and delays onset of Alzheimer's disease K Huang, E Marcora, AA Pimenova, AF Di Narzo, M Kapoor, SC Jin, ... Nature neuroscience 20 (8), 1052-1061, 2017 | 360 | 2017 |
Parsing the interferon transcriptional network and its disease associations S Mostafavi, H Yoshida, D Moodley, H LeBoité, K Rothamel, T Raj, CJ Ye, ... Cell 164 (3), 564-578, 2016 | 298 | 2016 |
A combined linkage-physical map of the human genome X Kong, K Murphy, T Raj, C He, PS White, TC Matise The American Journal of Human Genetics 75 (6), 1143-1148, 2004 | 271 | 2004 |
Intersection of population variation and autoimmunity genetics in human T cell activation CJ Ye, T Feng, HK Kwon, T Raj, MT Wilson, N Asinovski, C McCabe, ... Science 345 (6202), 1254665, 2014 | 265 | 2014 |
TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A AL Brown, OG Wilkins, MJ Keuss, SE Hill, M Zanovello, WC Lee, ... Nature 603 (7899), 131-137, 2022 | 258 | 2022 |
Postmortem cortex samples identify distinct molecular subtypes of ALS: retrotransposon activation, oxidative stress, and activated glia OH Tam, NV Rozhkov, R Shaw, D Kim, I Hubbard, S Fennessey, N Propp, ... Cell reports 29 (5), 1164-1177. e5, 2019 | 250 | 2019 |