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Richard Pouw
Richard Pouw
PhD, Group Leader at Sanquin Research
Verified email at sanquin.nl - Homepage
Title
Cited by
Cited by
Year
Developments in anti-complement therapy; from disease to clinical trial
CL Harris, RB Pouw, D Kavanagh, R Sun, D Ricklin
Molecular Immunology 102, 89-119, 2018
842018
Tipping the balance: intricate roles of the complement system in disease and therapy
RB Pouw, D Ricklin
Seminars in Immunopathology 43 (6), 757-771, 2021
742021
Of mice and men: the factor H protein family and complement regulation
RB Pouw, DW Vredevoogd, TW Kuijpers, D Wouters
Molecular Immunology 67 (1), 12-20, 2015
612015
Self-damage caused by dysregulation of the complement alternative pathway: relevance of the factor H protein family
P Sánchez-Corral, RB Pouw, M López-Trascasa, M Józsi
Frontiers in Immunology 9, 1607, 2018
592018
FHR-1 and FHR-2 form homo- and heterodimers, while FHR-5 circulates only as homodimer in human plasma
AE van Beek, RB Pouw, MC Brouwer, G van Mierlo, J Geissler, ...
Frontiers in Immunology 8, 1328, 2017
502017
Complement factor H-related protein 3 serum levels are low compared to factor H and mainly determined by gene copy number variation in CFHR3
RB Pouw, MC Brouwer, J Geissler, LV van Herpen, SS Zeerleder, ...
PLoS ONE 11 (3), e0152164, 2016
452016
TFPI inhibits lectin pathway of complement activation by direct interaction with MASP‐2
MP Keizer, RB Pouw, AM Kamp, S Patiwael, G Marsman, MH Hart, ...
European Journal of Immunology 45 (2), 544-550, 2015
342015
Complement regulator FHR-3 is elevated either locally or systemically in a selection of autoimmune diseases
N Schäfer, A Grosche, J Reinders, SM Hauck, RB Pouw, TW Kuijpers, ...
Frontiers in Immunology 7, 542, 2016
292016
High complement factor H-related (FHR)-3 levels are associated with the atypical hemolytic uremic syndrome-risk allele CFHR3*B
RB Pouw, I Gómez Delgado, A López Lera, S Rodríguez de Córdoba, ...
Frontiers in Immunology 9, 848, 2018
282018
Potentiation of complement regulator factor H protects human endothelial cells from complement attack in aHUS sera
RB Pouw, MC Brouwer, M de Gast, AE van Beek, LP van den Heuvel, ...
Blood Advances 3 (4), 621-632, 2019
252019
Complement factor H-related protein 4A is the dominant circulating splice variant of CFHR4
RB Pouw, MC Brouwer, AE Van Beek, M Józsi, D Wouters, TW Kuijpers
Frontiers in Immunology 9, 729, 2018
222018
Complement factor H contributes to mortality in humans and mice with bacterial meningitis
ES Kasanmoentalib, M Valls Serón, JY Engelen-Lee, MW Tanck, ...
Journal of neuroinflammation 16, 1-14, 2019
142019
The contribution of the alternative pathway in complement activation on cell surfaces depends on the strength of classical pathway initiation
ECW de Boer, AJF Thielen, JD Langereis, A Kamp, MC Brouwer, ...
Clinical & translational immunology 12 (1), e1436, 2023
92023
Sweet turning bitter: Carbohydrate sensing of complement in host defence and disease
R Hevey, RB Pouw, C Harris, D Ricklin
British journal of pharmacology 178 (14), 2802-2822, 2021
72021
Complement-regulatory biomaterial coatings: activity and selectivity profile of the factor H-binding peptide 5C6
C Bechtler, S Koutsogiannaki, E Umnyakova, A Hamid, A Gautam, ...
Acta Biomaterialia 155, 123-138, 2023
52023
Evaluating the clinical utility of measuring levels of factor H and the related proteins
P Banerjee, BRJ Veuskens, EG de Jorge, M Józsi, AJ Baeumner, ...
Molecular Immunology 151, 166-182, 2022
42022
Complement activation drives antibody-mediated transfusion-related acute lung injury via macrophage trafficking and formation of NETs
S van der Velden, TLJ van Osch, A Seghier, AEH Bentlage, JY Mok, ...
Blood 143 (1), 79-91, 2024
32024
Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations
V Kumar, RB Pouw, MI Autio, MG Sagmeister, ZY Phua, L Borghini, ...
The American Journal of Human Genetics 109 (9), 1680-1691, 2022
32022
Low Levels of Factor H Family Proteins During Meningococcal Disease Indicate Systemic Processes Rather Than Specific Depletion by Neisseria meningitidis
AE van Beek, RB Pouw, VJ Wright, N Sallah, D Inwald, C Hoggart, ...
Frontiers in immunology 13, 876776, 2022
32022
Complement & disease: out of the shadow into the spotlight
D Ricklin, RB Pouw
Seminars in Immunopathology 43, 755-756, 2021
32021
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