Ben Goult
Ben Goult
Professor of Mechanistic Cell Biology, University of Liverpool
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Cited by
Cited by
Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation
M Yao, BT Goult, H Chen, P Cong, MP Sheetz, J Yan
Scientific reports 4 (1), 1-7, 2014
The structure of an integrin/talin complex reveals the basis of inside‐out signal transduction
NJ Anthis, KL Wegener, F Ye, C Kim, BT Goult, ED Lowe, I Vakonakis, ...
The EMBO journal 28 (22), 3623-3632, 2009
The mechanical response of talin
M Yao, BT Goult, B Klapholz, X Hu, CP Toseland, Y Guo, P Cong, ...
Nature communications 7 (1), 11966, 2016
Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity
A Kumar, M Ouyang, K Van den Dries, EJ McGhee, K Tanaka, ...
Journal of Cell Biology 213 (3), 371-383, 2016
The structure of the C‐terminal actin‐binding domain of talin
AR Gingras, N Bate, BT Goult, L Hazelwood, I Canestrelli, JG Grossmann, ...
The EMBO journal 27 (2), 458-469, 2008
RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover
BT Goult, T Zacharchenko, N Bate, R Tsang, F Hey, AR Gingras, PR Elliott, ...
Journal of Biological Chemistry 288 (12), 8238-8249, 2013
Vinculin controls talin engagement with the actomyosin machinery
P Atherton, B Stutchbury, DY Wang, D Jethwa, R Tsang, ...
Nature communications 6 (1), 10038, 2015
Talin as a mechanosensitive signaling hub
BT Goult, J Yan, MA Schwartz
Journal of Cell Biology 217 (11), 3776-3784, 2018
Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery
J Oberoi, L Fairall, PJ Watson, JC Yang, Z Czimmerer, T Kampmann, ...
Nature structural & molecular biology 18 (2), 177-184, 2011
Structure of a double ubiquitin‐like domain in the talin head: a role in integrin activation
BT Goult, M Bouaouina, PR Elliott, N Bate, B Patel, AR Gingras, ...
The EMBO journal 29 (6), 1069-1080, 2010
Talin-KANK1 interaction controls the recruitment of cortical microtubule stabilizing complexes to focal adhesions
BP Bouchet, RE Gough, YC Ammon, D van de Willige, H Post, ...
Elife 5, e18124, 2016
The Structure of the talin head reveals a novel extended conformation of the FERM domain
PR Elliott, BT Goult, PM Kopp, N Bate, JG Grossmann, GCK Roberts, ...
Structure 18 (10), 1289-1299, 2010
Structural model and functional significance of pH-dependent talin–actin binding for focal adhesion remodeling
J Srivastava, G Barreiro, S Groscurth, AR Gingras, BT Goult, DR Critchley, ...
Proceedings of the National Academy of Sciences 105 (38), 14436-14441, 2008
The Structure of an Interdomain Complex That Regulates Talin Activity*♦
BT Goult, N Bate, NJ Anthis, KL Wegener, AR Gingras, B Patel, ...
Journal of biological chemistry 284 (22), 15097-15106, 2009
Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: implications for talin activation
BT Goult, XP Xu, AR Gingras, M Swift, B Patel, N Bate, PM Kopp, ...
Journal of structural biology 184 (1), 21-32, 2013
Talin dependent mechanosensitivity of cell focal adhesions
J Yan, M Yao, BT Goult, MP Sheetz
Cellular and molecular bioengineering 8, 151-159, 2015
The structure of the N-terminus of kindlin-1: a domain important for αIIbβ3 integrin activation
BT Goult, M Bouaouina, DS Harburger, N Bate, B Patel, NJ Anthis, ...
Journal of molecular biology 394 (5), 944-956, 2009
Structural determinants of integrin binding to the talin rod
AR Gingras, WH Ziegler, AA Bobkov, MG Joyce, D Fasci, M Himmel, ...
Journal of biological chemistry 284 (13), 8866-8876, 2009
The tale of two talins–two isoforms to fine‐tune integrin signalling
RE Gough, BT Goult
FEBS letters 592 (12), 2108-2125, 2018
The IDOL–UBE2D complex mediates sterol-dependent degradation of the LDL receptor
L Zhang, L Fairall, BT Goult, AC Calkin, C Hong, CJ Millard, P Tontonoz, ...
Genes & development 25 (12), 1262-1274, 2011
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