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Bob van de Water
Bob van de Water
Professor of Drug Safety Sciences, Leiden University
Verified email at lacdr.leidenuniv.nl
Title
Cited by
Cited by
Year
Endoplasmic reticulum chaperones GRP78 and calreticulin prevent oxidative stress, Ca2+ disturbances, and cell death in renal epithelial cells
H Liu, RC Bowes, B van de Water, C Sillence, JF Nagelkerke, JL Stevens
Journal of Biological Chemistry 272 (35), 21751-21759, 1997
4601997
E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial-to-mesenchymal transition in breast cancer cell lines
M Lombaerts, T Van Wezel, K Philippo, JWF Dierssen, RME Zimmerman, ...
British journal of cancer 94 (5), 661-671, 2006
4452006
A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies
SC Ramaiahgari, MW Den Braver, B Herpers, V Terpstra, ...
Archives of toxicology 88, 1083-1095, 2014
4212014
Cisplatin-induced nephrotoxicity in porcine proximal tubular cells: mitochondrial dysfunction by inhibition of complexes I to IV of the respiratory chain
M Kruidering, B Van De Water, E De Heer, GJ Mulder, JF Nagelkerke
Journal of Pharmacology and Experimental Therapeutics 280 (2), 638-649, 1997
3981997
Focal adhesion kinase: a potential target in cancer therapy
MJ van Nimwegen, B van de Water
Biochemical pharmacology 73 (5), 597-609, 2007
3752007
Adverse outcome pathways: opportunities, limitations and open questions
M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ...
Archives of Toxicology 91, 3477-3505, 2017
3242017
Endoplasmic reticulum stress proteins block oxidant-induced Ca2+ increases and cell death
H Liu, E Miller, B van de Water, JL Stevens
Journal of Biological Chemistry 273 (21), 12858-12862, 1998
2591998
Current EU research activities on combined exposure to multiple chemicals
SK Bopp, R Barouki, W Brack, S Dalla Costa, JLCM Dorne, PE Drakvik, ...
Environment international 120, 544-562, 2018
2242018
Annexin A1 regulates TGF-β signaling and promotes metastasis formation of basal-like breast cancer cells
M de Graauw, MH van Miltenburg, MK Schmidt, C Pont, R Lalai, ...
Proceedings of the National Academy of Sciences 107 (14), 6340-6345, 2010
2202010
Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development
U Marx, T Akabane, TB Andersson, E Baker, M Beilmann, S Beken, ...
Altex 37 (3), 365, 2020
2102020
Elevated insulin-like growth factor 1 receptor signaling induces antiestrogen resistance through the MAPK/ERK and PI3K/Akt signaling routes
Y Zhang, M Moerkens, S Ramaiahgari, H de Bont, L Price, J Meerman, ...
Breast cancer research 13, 1-16, 2011
2052011
Macrophage p53 deficiency leads to enhanced atherosclerosis in APOE* 3-Leiden transgenic mice
BJM van Vlijmen, G Gerritsen, AL Franken, LSM Boesten, MM Kockx, ...
Circulation research 88 (8), 780-786, 2001
1982001
Statement on advancing the assessment of chemical mixtures and their risks for human health and the environment
E Drakvik, R Altenburger, Y Aoki, T Backhaus, T Bahadori, R Barouki, ...
Environment international 134, 105267, 2020
1972020
The membrane attack complex of complement induces caspase activation and apoptosis
AJ Nauta, MR Daha, O Tijsma, B van de Water, F Tedesco, A Roos
European journal of immunology 32 (3), 783-792, 2002
1822002
Toxic tubular injury in kidneys from Pkd1-deletion mice accelerates cystogenesis accompanied by dysregulated planar cell polarity and canonical Wnt signaling …
H Happé, WN Leonhard, A van der Wal, B van de Water, ...
Human molecular genetics 18 (14), 2532-2542, 2009
1762009
Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models
RJ Weaver, EA Blomme, AE Chadwick, IM Copple, HHJ Gerets, ...
Nature Reviews Drug Discovery 19 (2), 131-148, 2020
1682020
Requirement for focal adhesion kinase in the early phase of mammary adenocarcinoma lung metastasis formation
MJ van Nimwegen, S Verkoeijen, L van Buren, D Burg, B van de Water
Cancer Research 65 (11), 4698-4706, 2005
1662005
A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration
K Yizhak, SE Le Dévédec, VM Rogkoti, F Baenke, VC De Boer, C Frezza, ...
Molecular systems biology 10 (8), 744, 2014
1622014
Toxicogenomics directory of chemically exposed human hepatocytes
M Grinberg, RM Stöber, K Edlund, E Rempel, P Godoy, R Reif, A Widera, ...
Archives of toxicology 88, 2261-2287, 2014
1492014
Restoration of chemosensitivity for doxorubicin and cisplatin in chondrosarcoma in vitro: BCL-2 family members cause chemoresistance
JG Van Oosterwijk, B Herpers, D Meijer, IH Briaire-de Bruijn, ...
Annals of oncology 23 (6), 1617-1626, 2012
1432012
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