David Cowburn
David Cowburn
Albert Einstein College of Medicine
Verified email at - Homepage
Cited by
Cited by
Accurate quantitation of protein expression and site-specific phosphorylation
Y Oda, K Huang, FR Cross, D Cowburn, BT Chait
Proceedings of the National Academy of Sciences 96 (12), 6591-6596, 1999
Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions
K Shuai, CM Horvath, LHT Huang, SA Qureshi, D Cowburn, JE Darnell Jr
Cell 76 (5), 821-828, 1994
Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms
G Waksman, SE Shoelson, N Pant, D Cowburn, J Kuriyan
Cell 72 (5), 779-790, 1993
Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides
G Waksman, D Kominos, SC Robertson, N Pant, D Baltimore, RB Birge, ...
Nature 358 (6388), 646-653, 1992
Modular peptide recognition domains in eukaryotic signaling
J Kuriyan, D Cowburn
Annual review of biophysics and biomolecular structure 26 (1), 259-288, 1997
Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists
JM McDonnell, D Fushman, CL Milliman, SJ Korsmeyer, D Cowburn
Cell 96 (5), 625-634, 1999
Perspectives on NMR in drug discovery: a technique comes of age
M Pellecchia, I Bertini, D Cowburn, C Dalvit, E Giralt, W Jahnke, TL James, ...
Nature Reviews Drug Discovery 7 (9), 738-745, 2008
A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV‐1 Nef protein.
CH Lee, B Leung, MA Lemmon, J Zheng, D Cowburn, J Kuriyan, ...
The EMBO journal 14 (20), 5006-5015, 1995
Identification of the binding site for acidic phospholipids on the pH domain of dynamin: implications for stimulation of GTPase activity
J Zheng, SM Cahill, MA Lemmon, D Fushman, J Schlessinger, ...
Journal of molecular biology 255 (1), 14-21, 1996
Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk
X Wu, B Knudsen, SM Feller, J Zheng, A Sali, D Cowburn, H Hanafusa, ...
Structure 3 (2), 215-226, 1995
Chemical ligation of folded recombinant proteins: segmental isotopic labeling of domains for NMR studies
R Xu, B Ayers, D Cowburn, TW Muir
Proceedings of the National Academy of Sciences 96 (2), 388-393, 1999
Long range hydrogen bond mediated effects in peptides: nitrogen-15 NMR study of gramicidin S in water and organic solvents
DH Live, DG Davis, WC Agosta, D Cowburn
Journal of the American Chemical Society 106 (7), 1939-1941, 1984
The main-chain dynamics of the dynamin pleckstrin homology (PH) domain in solution: analysis of 15N relaxation with monomer/dimer equilibration
D Fushman, S Cahill, D Cowburn
Journal of molecular biology 266 (1), 173-194, 1997
A cell-penetrating helical peptide as a potential HIV-1 inhibitor
H Zhang, Q Zhao, S Bhattacharya, AA Waheed, X Tong, A Hong, S Heck, ...
Journal of molecular biology 378 (3), 565-580, 2008
Three-dimensional solution structure of the src homology 2 domain of c-abl
M Overduin, CB Rios, BJ Mayer, D Baltimore, D Cowburn
Cell 70 (4), 697-704, 1992
Direct measurement of 15N chemical shift anisotropy in solution
D Fushman, N Tjandra, D Cowburn
Journal of the American Chemical Society 120 (42), 10947-10952, 1998
Mapping structural interactions using in-cell NMR spectroscopy (STINT-NMR)
DS Burz, K Dutta, D Cowburn, A Shekhtman
Nature methods 3 (2), 91-93, 2006
Semisynthesis of a segmental isotopically labeled protein splicing precursor: NMR evidence for an unusual peptide bond at the N-extein–intein junction
A Romanelli, A Shekhtman, D Cowburn, TW Muir
Proceedings of the National Academy of Sciences 101 (17), 6397-6402, 2004
The Affinity-Labeling of Partially Purified Acetylcholine Receptor from Electric Tissue of Electrophorus
A Karlin, D Cowburn
Proceedings of the National Academy of Sciences 70 (12), 3636-3640, 1973
A novel, specific interaction involving the Csk SH3 domain and its natural ligand
R Ghose, A Shekhtman, MJ Goger, H Ji, D Cowburn
Nature structural biology 8 (11), 998-1004, 2001
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