| Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein P Szewczyk, H Tao, AP McGrath, M Villaluz, SD Rees, SC Lee, R Doshi, ... Acta Crystallographica Section D: Biological Crystallography 71 (3), 732-741, 2015 | 180 | 2015 |
| Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure SCT Nicklisch, SD Rees, AP McGrath, T Gökirmak, LT Bonito, ... Science advances 2 (4), e1600001, 2016 | 111 | 2016 |
| Association of changes in air quality with bronchitic symptoms in children in California, 1993-2012 K Berhane, CC Chang, R McConnell, WJ Gauderman, E Avol, ... Jama 315 (14), 1491-1501, 2016 | 104 | 2016 |
| Cryo-EM structure of OSCA1.2 from Oryza sativa elucidates the mechanical basis of potential membrane hyperosmolality gating K Maity, JM Heumann, AP McGrath, NJ Kopcho, PK Hsu, CW Lee, ... Proceedings of the National Academy of Sciences 116 (28), 14309-14318, 2019 | 90 | 2019 |
| Cryo-EM structure of OSCA1.2 from Oryza sativa elucidates the mechanical basis of potential membrane hyperosmolality gating K Maity, JM Heumann, AP McGrath, NJ Kopcho, PK Hsu, CW Lee, ... Proceedings of the National Academy of Sciences 116 (28), 14309-14318, 2019 | 90 | 2019 |
| Science Advances (15 April 2016): Vol. 2, no. 4, e1600001 SCT Nicklisch, SD Rees, AP McGrath, T Gökirmak, LT Bonito, ... DOI, 0 | 85* | |
| Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates LS Zaramela, C Martino, F Alisson-Silva, SD Rees, SL Diaz, L Chuzel, ... Nature microbiology 4 (12), 2082-2089, 2019 | 67 | 2019 |
| Structural basis for GPCR-independent activation of heterotrimeric Gi proteins NA Kalogriopoulos, SD Rees, T Ngo, NJ Kopcho, AV Ilatovskiy, N Sun, ... Proceedings of the National Academy of Sciences 116 (33), 16394-16403, 2019 | 44 | 2019 |
| Structural basis for GPCR-independent activation of heterotrimeric Gi proteins NA Kalogriopoulos, SD Rees, T Ngo, NJ Kopcho, AV Ilatovskiy, N Sun, ... Proceedings of the National Academy of Sciences 116 (33), 16394-16403, 2019 | 44 | 2019 |
| Computational models in the service of X‐ray and cryo‐electron microscopy structure determination A Kryshtafovych, J Moult, R Albrecht, GA Chang, K Chao, A Fraser, ... Proteins: Structure, Function, and Bioinformatics 89 (12), 1633-1646, 2021 | 31 | 2021 |
| Transporter-interfering chemicals inhibit P-glycoprotein of yellowfin tuna (Thunnus albacares) SCT Nicklisch, AK Pouv, SD Rees, AP McGrath, G Chang, A Hamdoun Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2021 | 9 | 2021 |
| AlphaFold2 team (2021) A Kryshtafovych, J Moult, R Albrecht, GA Chang, K Chao, A Fraser, ... Proteins 89, 1633-1646, 0 | 8 | |
| Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure. Sci Adv. 2016; 2 (4): e1600001 SC Nicklisch, SD Rees, AP McGrath, T Gokirmak, LT Bonito, LM Vermeer Epub 2016/05/07. PubMed Central PMCID: PMC4846432. doi: 10.1126/sciadv …, 0 | 5 | |
| Cryo-EM structure of OSCA1.2 from Oryza sativa: Mechanical basis of hyperosmolality-gating in plants K Maity, J Heumann, AP McGrath, NJ Kopcho, PK Hsu, CW Lee, ... bioRxiv, 505453, 2018 | 3 | 2018 |
| Structure of a GEM‐complexed Gai Protein Provides Novel Insights into the Emerging Human GEMiome I Kufareva, N Kalogriopoulos, SD Rees, N Sun, N Aznar, G Chang, ... The FASEB Journal 31, 619.8-619.8, 2017 | 1 | 2017 |
| Structural Basis for Activation of Gαi by Non‐Receptor Guanine Nucleotide Exchange Modulators (GEMs) NA Kalogriopoulos, S Rees, N Aznar, N Sun, G Chang, P Ghosh, ... The FASEB Journal 31, 665.11-665.11, 2017 | 1 | 2017 |
| Novel sialidases and uses thereof K Zengler, A Varki, F Da Silva, S Diaz, C Martino, G Chang, S Rees, ... US Patent App. 17/006,293, 2021 | | 2021 |
| Structural basis for GPCR-independent activation of heterotrimeric Gi proteins (vol 116, pg 16394, 2019) NA Kalogriopoulos, SD Rees, T Ngo, NJ Kopcho, AV Ilatovskiy, N Sun, ... PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF …, 2019 | | 2019 |
| Evaluation of mechanisms of non-canonical G-protein signaling, membrane transporter dysregulation, and bacterial sialidase substrate preference using X-ray crystallography SD Rees University of California, San Diego, 2018 | | 2018 |
Aaron McGrathSenior Scientist, Takeda PharmaceuticalsVerified email at takeda.com
