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Jagat Adhikari
Jagat Adhikari
Covant Therapeutics
Verified email at covanttx.com
Title
Cited by
Cited by
Year
Thermodynamic analysis of protein-ligand binding interactions in complex biological mixtures using the stability of proteins from rates of oxidation
EC Strickland, MA Geer, DT Tran, J Adhikari, GM West, PD DeArmond, ...
Nature protocols 8 (1), 148-161, 2013
1442013
Human IFIT3 modulates IFIT1 RNA binding specificity and protein stability
B Johnson, LA VanBlargan, W Xu, JP White, C Shan, PY Shi, R Zhang, ...
Immunity 48 (3), 487-499. e5, 2018
1042018
Stable Isotope Labeling with Amino Acids in Cell Culture (SILAC)-based strategy for proteome-wide thermodynamic analysis of protein-ligand binding interactions
DT Tran, J Adhikari, MC Fitzgerald
Molecular & Cellular Proteomics 13 (7), 1800-1813, 2014
792014
Near-atomic structure of a giant virus
Q Fang, D Zhu, I Agarkova, J Adhikari, T Klose, Y Liu, Z Chen, Y Sun, ...
Nature communications 10 (1), 388, 2019
732019
SILAC-pulse proteolysis: A mass spectrometry-based method for discovery and cross-validation in proteome-wide studies of ligand binding
J Adhikari, MC Fitzgerald
Journal of the American Society for Mass Spectrometry 25 (12), 2073-2083, 2014
522014
An integrated approach for determining a protein–protein binding interface in solution and an evaluation of hydrogen–deuterium exchange kinetics for adjudicating candidate …
MM Zhang, BR Beno, RYC Huang, J Adhikari, EG Deyanova, J Li, G Chen, ...
Analytical chemistry 91 (24), 15709-15717, 2019
422019
Global analysis of protein folding thermodynamics for disease state characterization
J Adhikari, GM West, MC Fitzgerald
Journal of proteome research 14 (5), 2287-2297, 2015
372015
Mouse and human monoclonal antibodies protect against infection by multiple genotypes of Japanese encephalitis virus
E Fernandez, N Kose, MA Edeling, J Adhikari, G Sapparapu, SM Lazarte, ...
MBio 9 (1), 10.1128/mbio. 00008-18, 2018
352018
Predicting the structural basis of targeted protein degradation by integrating molecular dynamics simulations with structural mass spectrometry
T Dixon, D MacPherson, B Mostofian, T Dauzhenka, S Lotz, D McGee, ...
Nature communications 13 (1), 5884, 2022
282022
Dimerization controls Marburg virus VP24-dependent modulation of host antioxidative stress responses
B Johnson, J Li, J Adhikari, MR Edwards, H Zhang, T Schwarz, DW Leung, ...
Journal of molecular biology 428 (17), 3483-3494, 2016
272016
Calcium binding to the innate immune protein human calprotectin revealed by integrated mass spectrometry
J Adhikari, JR Stephan, DL Rempel, EM Nolan, ML Gross
Journal of the American Chemical Society 142 (31), 13372-13383, 2020
142020
Atomic-resolution prediction of degrader-mediated ternary complex structures by combining molecular simulations with hydrogen deuterium exchange
T Dixon, D MacPherson, B Mostofian, T Dauzhenka, S Lotz, D McGee, ...
Biorxiv, 2021.09. 26.461830, 2021
122021
Moderately Neutralizing Epitopes in Nonfunctional Regions Dominate the Antibody Response to Plasmodium falciparum EBA-140
ND Salinas, MM Paing, J Adhikari, ML Gross, N Tolia
Infection and immunity 87 (4), 10.1128/iai. 00716-18, 2019
102019
Hydrogen–deuterium exchange mass spectrometry identifies spatially distinct antibody epitopes on domain III of the Zika virus envelope protein
J Adhikari, H Zhao, E Fernandez, Y Huang, MS Diamond, DH Fremont, ...
Journal of mass spectrometry 56 (1), e4685, 2021
72021
Mouse and human monoclonal antibodies protect against infection by multiple genotypes of Japanese encephalitis virus. MBio. 9: e00008-18
E Fernandez, N Kose, MA Edeling, J Adhikari, G Sapparapu, SM Lazarte, ...
Article PubMed PubMed Central, 2018
72018
Mouse and Human Monoclonal Antibodies Protect against Infection by Multiple Genotypes of Japanese Encephalitis Virus. MBio. 2018; 9
E Fernandez, N Kose, MA Edeling, J Adhikari, G Sapparapu, SM Lazarte, ...
PubMed Central PMCID: PMC5829823, 0
7
Near-atomic structure of a giant virus. Nat Commun 10: 388
Q Fang, D Zhu, I Agarkova, J Adhikari, T Klose, Y Liu, Z Chen, Y Sun, ...
62019
Kinetic Isotope Effects and Hydrogen/Deuterium Exchange Reveal Large Conformational Changes During the Catalysis of the Clostridium acetobutylicum Spore …
L Yang, J Adhikari, ML Gross, L Li
Photochemistry and photobiology 93 (1), 331-342, 2017
52017
Binding of IFIT1 by IFIT3 modulates protein stability and RNA binding specificity
B Johnson, LA VanBlargan, W Xu, JP White, C Shan, PY Shi, R Zhang, ...
Immunity 48 (3), 487, 2018
42018
Structural vaccinology for malaria: Host-pathogen interactions, broadly-neutralizing antibodies and immunogen design
E Chen, D Urusova, ND Salinas, F Ntumngia, L Carias, Y Huang, ...
Acta Crystallographica Section A: Foundations and Advances 74, a160-a160, 2018
12018
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