PINK1 cleavage at position A103 by the mitochondrial protease PARL E Deas, H Plun-Favreau, S Gandhi, H Desmond, S Kjaer, SHY Loh, ... Human molecular genetics 20 (5), 867-879, 2011 | 523 | 2011 |
Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS CE Hall, Z Yao, M Choi, GE Tyzack, A Serio, R Luisier, J Harley, E Preza, ... Cell reports 19 (9), 1739-1749, 2017 | 180 | 2017 |
Mitofusin-mediated ER stress triggers neurodegeneration in pink1/parkin models of Parkinson’s disease I Celardo, AC Costa, S Lehmann, C Jones, N Wood, NE Mencacci, ... Cell death & disease 7 (6), e2271-e2271, 2016 | 168 | 2016 |
Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson’s disease R Tufi, S Gandhi, IP De Castro, S Lehmann, PR Angelova, D Dinsdale, ... Nature cell biology 16 (2), 157-166, 2014 | 163 | 2014 |
Genetic analysis of mitochondrial protein misfolding in Drosophila melanogaster I Pimenta de Castro, AC Costa, D Lam, R Tufi, V Fedele, N Moisoi, ... Cell Death & Differentiation 19 (8), 1308-1316, 2012 | 133 | 2012 |
Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson’s disease AC Costa, SHY Loh, LM Martins Cell death & disease 4 (1), e467-e467, 2013 | 128 | 2013 |
Identification of new kinase clusters required for neurite outgrowth and retraction by a loss-of-function RNA interference screen SHY Loh, L Francescut, P Lingor, M Bähr, P Nicotera Cell Death & Differentiation 15 (2), 283-298, 2008 | 120 | 2008 |
Enhancing NAD+ salvage metabolism is neuroprotective in a PINK1 model of Parkinson's disease S Lehmann, SHY Loh, LM Martins Biology open 6 (2), 141-147, 2017 | 98 | 2017 |
Parp mutations protect against mitochondrial dysfunction and neurodegeneration in a PARKIN model of Parkinson’s disease S Lehmann, AC Costa, I Celardo, SHY Loh, LM Martins Cell death & disease 7 (3), e2166-e2166, 2016 | 77 | 2016 |
Mitochondrial quality control and Parkinson’s disease: a pathway unfolds IP de Castro, LM Martins, SHY Loh Molecular neurobiology 43, 80-86, 2011 | 69 | 2011 |
dATF4 regulation of mitochondrial folate-mediated one-carbon metabolism is neuroprotective I Celardo, S Lehmann, AC Costa, SHY Loh, L Miguel Martins Cell Death & Differentiation 24 (4), 638-648, 2017 | 62 | 2017 |
MAP4K3 modulates cell death via the post-transcriptional regulation of BH3-only proteins D Lam, D Dickens, EB Reid, SHY Loh, N Moisoi, LM Martins Proceedings of the National Academy of Sciences 106 (29), 11978-11983, 2009 | 52 | 2009 |
Forcing contacts between mitochondria and the endoplasmic reticulum extends lifespan in a Drosophila model of Alzheimer's disease J Garrido-Maraver, SHY Loh, LM Martins Biology Open 9 (1), bio047530, 2020 | 48 | 2020 |
Drosophila ref (2) P is required for the parkin-mediated suppression of mitochondrial dysfunction in pink1 mutants IP De Castro, AC Costa, I Celardo, R Tufi, D Dinsdale, SHY Loh, ... Cell death & disease 4 (10), e873-e873, 2013 | 45 | 2013 |
A Drosophila group E Sox gene is dynamically expressed in the embryonic alimentary canal SHY Loh, S Russell Mechanisms of Development 93 (1-2), 185-188, 2000 | 45 | 2000 |
Mitochondrial complex I derived ROS regulate stress adaptation in Drosophila melanogaster F Scialò, A Sriram, R Stefanatos, RV Spriggs, SHY Loh, LM Martins, ... Redox biology 32, 101450, 2020 | 42 | 2020 |
Nonsyndromic Parkinson disease in a family with autosomal dominant optic atrophy due to OPA1 mutations DS Lynch, SHY Loh, J Harley, AJ Noyce, LM Martins, NW Wood, ... Neurology: Genetics 3 (5), e188, 2017 | 28 | 2017 |
Parp mutations protect from mitochondrial toxicity in Alzheimer’s disease Y Yu, G Fedele, I Celardo, SHY Loh, LM Martins Cell Death & Disease 12 (7), 651, 2021 | 25 | 2021 |
Drosophila happyhour modulates JNK-dependent apoptosis D Lam, S Shah, IP de Castro, SHY Loh, LM Martins Cell death & disease 1 (8), e66-e66, 2010 | 25 | 2010 |
Enhancing folic acid metabolism suppresses defects associated with loss of Drosophila mitofusin J Garrido-Maraver, I Celardo, AC Costa, S Lehmann, SHY Loh, ... Cell Death & Disease 10 (4), 288, 2019 | 12 | 2019 |