| Early lactate clearance is associated with biomarkers of inflammation, coagulation, apoptosis, organ dysfunction and mortality in severe sepsis and septic shock HB Nguyen, M Loomba, JJ Yang, G Jacobsen, K Shah, RM Otero, ... Journal of inflammation 7, 1-11, 2010 | 320 | 2010 |
| Host gene expression classifiers diagnose acute respiratory illness etiology EL Tsalik, R Henao, M Nichols, T Burke, ER Ko, MT McClain, LL Hudson, ... Science translational medicine 8 (322), 322ra11-322ra11, 2016 | 245 | 2016 |
| Early goal-directed therapy in severe sepsis and septic shock: insights and comparisons to ProCESS, ProMISe, and ARISE HB Nguyen, AK Jaehne, N Jayaprakash, MW Semler, S Hegab, ... Critical Care 20, 1-16, 2016 | 230 | 2016 |
| Early interventions in severe sepsis and septic shock: a review of the evidence one decade later EP Rivers, M Katranji, KA Jaehne, S Brown, G Abou Dagher, C Cannon, ... Minerva anestesiologica 78 (6), 712, 2012 | 226 | 2012 |
| Effect of vitamin C, thiamine, and hydrocortisone on ventilator-and vasopressor-free days in patients with sepsis: the VICTAS randomized clinical trial JE Sevransky, RE Rothman, DN Hager, GR Bernard, SM Brown, ... Jama 325 (8), 742-750, 2021 | 200 | 2021 |
| An integrated transcriptome and expressed variant analysis of sepsis survival and death EL Tsalik, RJ Langley, DL Dinwiddie, NA Miller, B Yoo, ... Genome medicine 6, 1-15, 2014 | 95 | 2014 |
| Early biomarker activity in severe sepsis and septic shock and a contemporary review of immunotherapy trials: not a time to give up, but to give it earlier EP Rivers, AK Jaehne, HB Nguyen, DG Papamatheakis, D Singer, ... Shock 39 (2), 127-137, 2013 | 87 | 2013 |
| Fluid therapy in septic shock EP Rivers, AK Jaehne, L Eichhorn-Wharry, S Brown, D Amponsah Current Opinion in Critical Care 16 (4), 297-308, 2010 | 75 | 2010 |
| The incidence and significance of bacteremia in out of hospital cardiac arrest V Coba, AK Jaehne, A Suarez, G Abou Dagher, SC Brown, JJ Yang, ... Resuscitation 85 (2), 196-202, 2014 | 69 | 2014 |
| Oxygen extraction and perfusion markers in severe sepsis and septic shock: diagnostic, therapeutic and outcome implications EP Rivers, AC Yataco, AK Jaehne, J Gill, M Disselkamp Current opinion in critical care 21 (5), 381-387, 2015 | 50 | 2015 |
| Renal systems biology of patients with systemic inflammatory response syndrome EL Tsalik, LK Willig, BJ Rice, JC Van Velkinburgh, RP Mohney, ... Kidney international 88 (4), 804-814, 2015 | 50 | 2015 |
| Validation of a host response test to distinguish bacterial and viral respiratory infection EC Lydon, R Henao, TW Burke, M Aydin, BP Nicholson, SW Glickman, ... EBioMedicine 48, 453-461, 2019 | 48 | 2019 |
| Discriminating bacterial and viral infection using a rapid host gene expression test EL Tsalik, R Henao, JL Montgomery, JW Nawrocki, M Aydin, EC Lydon, ... Critical care medicine 49 (10), 1651-1663, 2021 | 44 | 2021 |
| Early liberal fluid therapy for sepsis patients is not harmful: Hydrophobia is unwarranted but drink responsibly AK Jaehne, EP Rivers Critical care medicine 44 (12), 2263-2269, 2016 | 30 | 2016 |
| The association between blood glucose levels and matrix-metalloproteinase-9 in early severe sepsis and septic shock GR Sachwani, AK Jaehne, N Jayaprakash, M Kuzich, V Onkoba, ... Journal of Inflammation 13, 1-8, 2016 | 25 | 2016 |
| A physiologic approach to hemodynamic monitoring and optimizing oxygen delivery in shock resuscitation A Russell, EP Rivers, PC Giri, AK Jaehne, HB Nguyen Journal of clinical medicine 9 (7), 2052, 2020 | 21 | 2020 |
| Evaluating the discriminating capacity of cell death (apoptotic) biomarkers in sepsis C Duplessis, M Gregory, K Frey, M Bell, L Truong, K Schully, J Lawler, ... Journal of intensive care 6, 1-11, 2018 | 20 | 2018 |
| Plasma levels of F-actin and F: G-actin ratio as potential new biomarkers in patients with septic shock JB Belsky, DC Morris, R Bouchebl, MR Filbin, KR Bobbitt, AK Jaehne, ... Biomarkers 21 (2), 180-185, 2016 | 17 | 2016 |
| Prospective validation of a rapid host gene expression test to discriminate bacterial from viral respiratory infection ER Ko, R Henao, K Frankey, EA Petzold, PD Isner, AK Jaehne, N Allen, ... JAMA network Open 5 (4), e227299-e227299, 2022 | 15 | 2022 |
| Proteomic profiles of exosomes of septic patients presenting to the emergency department compared to healthy controls DC Morris, AK Jaehne, M Chopp, Z Zhang, L Poisson, Y Chen, I Datta, ... Journal of clinical medicine 9 (9), 2930, 2020 | 13 | 2020 |
Rivers, EWayne State UniversityVerified email at hfhs.org
