Selective nanovector mediated treatment of activated proinflammatory microglia/macrophages in spinal cord injury S Papa, F Rossi, R Ferrari, A Mariani, M De Paola, I Caron, F Fiordaliso, ... ACS nano 7 (11), 9881-9895, 2013 | 152 | 2013 |
Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation M Peviani, E Salvaneschi, L Bontempi, A Petese, A Manzo, D Rossi, ... Neurobiology of disease 62, 218-232, 2014 | 135 | 2014 |
Accumulation of human SOD1 and ubiquitinated deposits in the spinal cord of SOD1G93A mice during motor neuron disease progression correlates with a decrease of proteasome C Cheroni, M Peviani, P Cascio, S Debiasi, C Monti, C Bendotti Neurobiology of disease 18 (3), 509-522, 2005 | 124 | 2005 |
Polymeric nanoparticle system to target activated microglia/macrophages in spinal cord injury S Papa, R Ferrari, M De Paola, F Rossi, A Mariani, I Caron, E Sammali, ... Journal of controlled release 174, 15-26, 2014 | 113 | 2014 |
Multiple drug delivery hydrogel system for spinal cord injury repair strategies G Perale, F Rossi, M Santoro, M Peviani, S Papa, D Llupi, P Torriani, ... Journal of controlled release 159 (2), 271-280, 2012 | 110 | 2012 |
Neuroprotective effects of toll-like receptor 4 antagonism in spinal cord cultures and in a mouse model of motor neuron degeneration M De Paola, A Mariani, P Bigini, M Peviani, G Ferrara, M Molteni, ... Molecular medicine 18, 971-981, 2012 | 77 | 2012 |
Differences in protein quality control correlate with phenotype variability in 2 mouse models of familial amyotrophic lateral sclerosis M Marino, S Papa, V Crippa, G Nardo, M Peviani, C Cheroni, MC Trolese, ... Neurobiology of Aging 36 (1), 492-504, 2015 | 68 | 2015 |
Identification of a potent and selective σ1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells D Rossi, A Pedrali, M Urbano, R Gaggeri, M Serra, L Fernández, ... Bioorganic & medicinal chemistry 19 (21), 6210-6224, 2011 | 56 | 2011 |
Inter-and intracellular signaling in amyotrophic lateral sclerosis: role of p38 mitogen-activated protein kinase C Bendotti, M Bao Cutrona, C Cheroni, G Grignaschi, D Lo Coco, ... Neurodegenerative Diseases 2 (3-4), 128-134, 2006 | 51 | 2006 |
Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC‐33 compounds: promising neuroprotective agents acting as σ1 receptor agonists D Rossi, A Pedrali, R Gaggeri, A Marra, L Pignataro, E Laurini, V Dal Col, ... ChemMedChem 8 (9), 1514-1527, 2013 | 48 | 2013 |
Identification of RC-33 as a potent and selective σ1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-Scale synthesis, physicochemical … D Rossi, A Marra, P Picconi, M Serra, L Catenacci, M Sorrenti, E Laurini, ... Bioorganic & medicinal chemistry 21 (9), 2577-2586, 2013 | 44 | 2013 |
Intracerebroventricular delivery of hematopoietic progenitors results in rapid and robust engraftment of microglia-like cells A Capotondo, R Milazzo, JM Garcia-Manteiga, E Cavalca, A Montepeloso, ... Science advances 3 (12), e1701211, 2017 | 43 | 2017 |
Biodegradable polymeric nanoparticles administered in the cerebrospinal fluid: Brain biodistribution, preferential internalization in microglia and implications for cell … M Peviani, UC Palmiero, F Cecere, R Milazzo, D Moscatelli, A Biffi Biomaterials 209, 25-40, 2019 | 41 | 2019 |
Lack of changes in the PI3K/AKT survival pathway in the spinal cord motor neurons of a mouse model of familial amyotrophic lateral sclerosis M Peviani, C Cheroni, F Troglio, M Quarto, G Pelicci, C Bendotti Molecular and Cellular Neuroscience 34 (4), 592-602, 2007 | 39 | 2007 |
Specific induction of Akt3 in spinal cord motor neurons is neuroprotective in a mouse model of familial amyotrophic lateral sclerosis M Peviani, M Tortarolo, E Battaglia, R Piva, C Bendotti Molecular neurobiology 49, 136-148, 2014 | 37 | 2014 |
Unraveling the complexity of amyotrophic lateral sclerosis: recent advances from the transgenic mutant SOD1 mice M Peviani, I Caron, C Pizzasegola, F Gensano, M Tortarolo, C Bendotti CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2010 | 37 | 2010 |
Toward the identification of neuroprotective agents: g-scale synthesis, pharmacokinetic evaluation and CNS distribution of (R)-RC-33, a promising Sigma1 receptor … A Marra, D Rossi, L Pignataro, C Bigogno, A Canta, N Oggioni, ... Future medicinal chemistry 8 (3), 287-295, 2016 | 35 | 2016 |
Lentiviral vectors carrying enhancer elements of Hb9 promoter drive selective transgene expression in mouse spinal cord motor neurons M Peviani, M Kurosaki, M Terao, D Lidonnici, F Gensano, E Battaglia, ... Journal of neuroscience methods 205 (1), 139-147, 2012 | 30 | 2012 |
In situ agar–carbomer hydrogel polycondensation: A chemical approach to regenerative medicine G Perale, P Veglianese, F Rossi, M Peviani, M Santoro, D Llupi, E Micotti, ... Materials letters 65 (11), 1688-1692, 2011 | 30 | 2011 |
Studies on the Enantiomers of RC-33 as Neuroprotective Agents: Isolation, Configurational Assignment, and Preliminary Biological Profile D Rossi, A Pedrali, A Marra, L Pignataro, D Schepmann, B Wünsch, L Ye, ... Chirality 25 (11), 814-822, 2013 | 28 | 2013 |