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Karen McLean
Karen McLean
Gynecologic Oncology, Roswell Park Comprehensive Cancer Center
Verified email at roswellpark.org
Title
Cited by
Cited by
Year
The SLUG zinc-finger protein represses E-cadherin in breast cancer
KM Hajra, DYS Chen, ER Fearon
Cancer research 62 (6), 1613-1618, 2002
13002002
Aldehyde dehydrogenase in combination with CD133 defines angiogenic ovarian cancer stem cells that portend poor patient survival
IA Silva, S Bai, K McLean, K Yang, K Griffith, D Thomas, C Ginestier, ...
Cancer research 71 (11), 3991-4001, 2011
5912011
Cadherin and catenin alterations in human cancer
KM Hajra, ER Fearon
Genes, Chromosomes and Cancer 34 (3), 255-268, 2002
5102002
Ovarian cancer, version 2.2020, NCCN clinical practice guidelines in oncology
DK Armstrong, RD Alvarez, JN Bakkum-Gamez, L Barroilhet, K Behbakht, ...
Journal of the National Comprehensive Cancer Network 19 (2), 191-226, 2021
4672021
Human ovarian carcinoma–associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production
K McLean, Y Gong, Y Choi, N Deng, K Yang, S Bai, L Cabrera, E Keller, ...
The Journal of clinical investigation 121 (8), 3206-3219, 2011
3942011
Apoptosome dysfunction in human cancer
KM Hajra, JR Liu
Apoptosis 9, 691-704, 2004
3772004
Cancer SLC43A2 alters T cell methionine metabolism and histone methylation
Y Bian, W Li, DM Kremer, P Sajjakulnukit, S Li, J Crespo, ZC Nwosu, ...
Nature 585 (7824), 277-282, 2020
3282020
γ-Catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of β-catenin
FT Kolligs, B Kolligs, KM Hajra, G Hu, M Tani, KR Cho, ER Fearon
Genes & development 14 (11), 1319-1331, 2000
2812000
NCCN guidelines insights: Ovarian cancer, version 1.2019: Featured updates to the NCCN guidelines
DK Armstrong, RD Alvarez, JN Bakkum-Gamez, L Barroilhet, K Behbakht, ...
Journal of the National Comprehensive Cancer Network 17 (8), 896-909, 2019
2312019
Association between life purpose and mortality among US adults older than 50 years
A Alimujiang, A Wiensch, J Boss, NL Fleischer, AM Mondul, K McLean, ...
JAMA network open 2 (5), e194270-e194270, 2019
2042019
The flipped classroom for medical students
H Morgan, K McLean, C Chapman, J Fitzgerald, A Yousuf, M Hammoud
The clinical teacher 12 (3), 155-160, 2015
1962015
E-cadherin is a WT1 target gene
S Hosono, I Gross, MA English, KM Hajra, ER Fearon, JD Licht
Journal of Biological Chemistry 275 (15), 10943-10953, 2000
1672000
NCCN guidelines® insights: Ovarian cancer, version 3.2022: Featured updates to the NCCN guidelines
DK Armstrong, RD Alvarez, FJ Backes, JN Bakkum-Gamez, L Barroilhet, ...
Journal of the National Comprehensive Cancer Network 20 (9), 972-980, 2022
1372022
Human carcinoma-associated mesenchymal stem cells promote ovarian cancer chemotherapy resistance via a BMP4/HH signaling loop
LG Coffman, YJ Choi, K McLean, BL Allen, MP di Magliano, ...
Oncotarget 7 (6), 6916, 2016
1362016
Extinction of E-cadherin expression in breast cancer via a dominant repression pathway acting on proximal promoter elements
KM Hajra, X Ji, ER Fearon
Oncogene 18 (51), 7274-7279, 1999
1351999
Phase II clinical trial of metformin as a cancer stem cell–targeting agent in ovarian cancer
JR Brown, DK Chan, JJ Shank, KA Griffith, H Fan, R Szulawski, K Yang, ...
JCI insight 5 (11), 2020
1342020
CD24+ Ovarian Cancer Cells Are Enriched for Cancer-Initiating Cells and Dependent on JAK2 Signaling for Growth and Metastasis
D Burgos-Ojeda, R Wu, K McLean, YC Chen, M Talpaz, E Yoon, KR Cho, ...
Molecular cancer therapeutics 14 (7), 1717-1727, 2015
932015
Personalized medicine–based approach to model patterns of chemoresistance and tumor recurrence using ovarian cancer stem cell spheroids
S Raghavan, P Mehta, MR Ward, ME Bregenzer, EMA Fleck, L Tan, ...
Clinical Cancer Research 23 (22), 6934-6945, 2017
912017
Identifying alemtuzumab as an anti-myeloid cell antiangiogenic therapy for the treatment of ovarian cancer
HL Pulaski, G Spahlinger, IA Silva, K McLean, AS Kueck, RK Reynolds, ...
Journal of translational medicine 7, 1-14, 2009
802009
Leukemia inhibitory factor functions in parallel with interleukin-6 to promote ovarian cancer growth
K McLean, L Tan, DE Bolland, LG Coffman, LF Peterson, M Talpaz, ...
Oncogene 38 (9), 1576-1584, 2019
732019
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