Bharath Srinivasan
Bharath Srinivasan
Mechanistic Chemist/Biologist and Enzymologist
Verified email at - Homepage
Cited by
Cited by
Synthesis of novel coumarin appended bis (formylpyrazole) derivatives: Studies on their antimicrobial and antioxidant activities
R Nagamallu, B Srinivasan, MB Ningappa, AK Kariyappa
Bioorganic & medicinal chemistry letters 26 (2), 690-694, 2016
A guide to the Michaelis–Menten equation: steady state and beyond
B Srinivasan
The FEBS journal 289 (20), 6086-6098, 2022
Elucidation of the substrate specificity, kinetic and catalytic mechanism of adenylosuccinate lyase from Plasmodium falciparum
V Bulusu, B Srinivasan, MP Bopanna, H Balaram
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1794 (4), 642-654, 2009
Words of advice: teaching enzyme kinetics
B Srinivasan
The FEBS journal 288 (7), 2068-2083, 2021
Synthesis of agarose-metal/semiconductor nanoparticles having superior bacteriocidal activity and their simple conversion to metal-carbon composites
KKR Datta, B Srinivasan, H Balaram, M Eswaramoorthy
Journal of Chemical Sciences 120, 579-586, 2008
Design and environmentally benign synthesis of novel thiophene appended pyrazole analogues as anti-inflammatory and radical scavenging agents: Crystallographic, in silico …
MG Prabhudeva, S Bharath, AD Kumar, S Naveen, NK Lokanath, ...
Bioorganic Chemistry 73, 109-120, 2017
Chemical space of Escherichia coli dihydrofolate reductase inhibitors: New approaches for discovering novel drugs for old bugs
B Srinivasan*, S Tonddast‐Navaei, A Roy §, H Zhou, J Skolnick
Medicinal research reviews 39 (2), 684-705, 2019
Synthesis of novel 2-pyrazoline analogues with potent anti-inflammatory effect mediated by inhibition of phospholipase A2: Crystallographic, in silico docking and QSAR analysis
DM Lokeshwari, DK Achutha, B Srinivasan, N Shivalingegowda, ...
Bioorganic & Medicinal Chemistry Letters 27 (16), 3806-3811, 2017
PoLi: A Virtual Screening Pipeline Based on Template Pocket and Ligand Similarity
A Roy, B Srinivasan, J Skolnick
Journal of chemical information and modeling 55 (8), 1757-1770, 2015
Explicit Treatment of Non Michaelis-Menten and Atypical Kinetics in Early Drug Discovery
B Srinivasan
ChemMedChem, 2020
Allosteric regulation and substrate activation in cytosolic nucleotidase II from Legionella pneumophila
B Srinivasan, F Forouhar, A Shukla, C Sampangi, S Kulkarni, ...
The FEBS journal 281 (6), 1613-1628, 2014
Repurposing FDA-approved drugs for anti-aging therapies
TW Snell, RK Johnston, B Srinivasan, H Zhou, M Gao, J Skolnick
Biogerontology, 1-14, 2016
Synthesis of lignan conjugates via cyclopropanation: Antimicrobial and antioxidant studies
KR Raghavendra, N Renuka, VH Kameshwar, B Srinivasan, KA Kumar, ...
Bioorganic & Medicinal Chemistry Letters 26 (15), 3621-3625, 2016
Insights into the slow‐onset tight‐binding inhibition of Escherichia coli dihydrofolate reductase: detailed mechanistic characterization of pyrrolo [3,2‐f] quinazoline …
B Srinivasan, J Skolnick
The FEBS journal 282 (10), 1922-1938, 2015
Implications of the small number of distinct ligand binding pockets in proteins for drug discovery, evolution and biochemical function
J Skolnick, M Gao, A Roy, B Srinivasan, H Zhou
Bioorganic & medicinal chemistry letters 25 (6), 1163-1170, 2015
Stable inheritance of CENP-A chromatin: Inner strength versus dynamic control
S Mitra, B Srinivasan, LET Jansen
Journal of Cell Biology 219 (10), e202005099, 2020
Design, synthesis of novel furan appended benzothiazepine derivatives and in vitro biological evaluation as potent VRV-PL-8a and H+/K+ ATPase inhibitors
DM Lokeshwari, ND Rekha, B Srinivasan, HK Vivek, AK Kariyappa
Bioorganic & Medicinal Chemistry Letters 27 (14), 3048-3054, 2017
Ligand binding studies, preliminary structure–activity relationship and detailed mechanistic characterization of 1-phenyl-6, 6-dimethyl-1, 3, 5-triazine-2, 4-diamine …
B Srinivasan, S Tonddast-Navaei, J Skolnick
European journal of medicinal chemistry 103, 600-614, 2015
Experimental validation of FINDSITEcomb virtual ligand screening results for eight proteins yields novel nanomolar and micromolar binders
B Srinivasan, H Zhou, J Kubanek, J Skolnick
Journal of cheminformatics 6, 1-14, 2014
Design and Amberlyst-15 mediated synthesis of novel thienyl-pyrazole carboxamides that potently inhibit Phospholipase A2 by binding to an allosteric site on the enzyme
AD Kumar, MG Prabhudeva, S Bharath, K Kumara, NK Lokanath, ...
Bioorganic Chemistry 80, 444-452, 2018
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