| Using mini-prep plasmid DNA for sequencing double stranded templates with Sequenase. R Kraft, J Tardiff, KS Krauter, LA Leinwand | 713 | 1988 |
| Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy JC Tardiff, TE Hewett, BM Palmer, C Olsson, SM Factor, RL Moore, ... The Journal of clinical investigation 104 (4), 469-481, 1999 | 273 | 1999 |
| A truncated cardiac troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy. JC Tardiff, SM Factor, BD Tompkins, TE Hewett, BM Palmer, RL Moore, ... The Journal of clinical investigation 101 (12), 2800-2811, 1998 | 248 | 1998 |
| Interactions and developmental effects of mutations in the Broad-Complex of Drosophila melanogaster. I Kiss, AH Beaton, J Tardiff, D Fristrom, JW Fristrom Genetics 118 (2), 247-259, 1988 | 248 | 1988 |
| Sarcomeric proteins and familial hypertrophic cardiomyopathy: linking mutations in structural proteins to complex cardiovascular phenotypes JC Tardiff Heart failure reviews 10, 237-248, 2005 | 234 | 2005 |
| Expression of the β (slow)-isoform of MHC in the adult mouse heart causes dominant-negative functional effects JC Tardiff, TE Hewett, SM Factor, KL Vikstrom, J Robbins, LA Leinwand American journal of physiology-Heart and Circulatory Physiology 278 (2 …, 2000 | 188 | 2000 |
| Thin filament mutations: developing an integrative approach to a complex disorder JC Tardiff Circulation research 108 (6), 765-782, 2011 | 187 | 2011 |
| Clinical phenotype and outcome of hypertrophic cardiomyopathy associated with thin-filament gene mutations R Coppini, CY Ho, E Ashley, S Day, C Ferrantini, F Girolami, B Tomberli, ... Journal of the American College of Cardiology 64 (24), 2589-2600, 2014 | 155 | 2014 |
| Targets for therapy in sarcomeric cardiomyopathies JC Tardiff, L Carrier, DM Bers, C Poggesi, C Ferrantini, R Coppini, ... Cardiovascular research 105 (4), 457-470, 2015 | 154 | 2015 |
| Decreased energetics in murine hearts bearing the R92Q mutation in cardiac troponin T MM Javadpour, JC Tardiff, I Pinz, JS Ingwall The Journal of clinical investigation 112 (5), 768-775, 2003 | 153 | 2003 |
| Mechanochemotransduction during cardiomyocyte contraction is mediated by localized nitric oxide signaling Z Jian, H Han, T Zhang, J Puglisi, LT Izu, JA Shaw, E Onofiok, JR Erickson, ... Science signaling 7 (317), ra27-ra27, 2014 | 140 | 2014 |
| Ca2+ activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin T M Chandra, VLM Rundell, JC Tardiff, LA Leinwand, PP De Tombe, ... American Journal of Physiology-Heart and Circulatory Physiology 280 (2 …, 2001 | 128 | 2001 |
| Increase in tension-dependent ATP consumption induced by cardiac troponin T mutation M Chandra, ML Tschirgi, JC Tardiff American Journal of Physiology-Heart and Circulatory Physiology 289 (5 …, 2005 | 97 | 2005 |
| A model of calcium activation of the cardiac thin filament EP Manning, JC Tardiff, SD Schwartz Biochemistry 50 (34), 7405-7413, 2011 | 93 | 2011 |
| Ranolazine prevents phenotype development in a mouse model of hypertrophic cardiomyopathy R Coppini, L Mazzoni, C Ferrantini, F Gentile, JM Pioner, A Laurino, ... Circulation: Heart Failure 10 (3), e003565, 2017 | 92 | 2017 |
| Cardiac troponin T mutations: correlation between the type of mutation and the nature of myofilament dysfunction in transgenic mice DE Montgomery, JC Tardiff, M Chandra The Journal of physiology 536 (2), 583-592, 2001 | 88 | 2001 |
| Changes in the chemical and dynamic properties of cardiac troponin T cause discrete cardiomyopathies in transgenic mice BR Ertz-Berger, H He, C Dowell, SM Factor, TE Haim, S Nunez, ... Proceedings of the National Academy of Sciences 102 (50), 18219-18224, 2005 | 87 | 2005 |
| Temporal and mutation-specific alterations in Ca2+ homeostasis differentially determine the progression of cTnT-related cardiomyopathies in murine models PJ Guinto, TE Haim, CC Dowell-Martino, N Sibinga, JC Tardiff American Journal of Physiology-Heart and Circulatory Physiology 297 (2 …, 2009 | 81 | 2009 |
| Synergistic role of ADP and Ca2+ in diastolic myocardial stiffness V Sequeira, A Najafi, M McConnell, ED Fowler, IAE Bollen, RCI Wüst, ... The Journal of physiology 593 (17), 3899-3916, 2015 | 77 | 2015 |
| R-92L and R-92W mutations in cardiac troponin T lead to distinct energetic phenotypes in intact mouse hearts H He, MM Javadpour, F Latif, JC Tardiff, JS Ingwall Biophysical journal 93 (5), 1834-1844, 2007 | 75 | 2007 |
