| Biocatalysis: A Pharma Perspective JP Adams, MJB Brown, AD Rodriguez, RC Lloyd, GD Roiban Advanced Synthesis & Catalysis, 2019 | 216 | 2019 |
| Chiral synthesis of LSD1 inhibitor GSK2879552 enabled by directed evolution of an imine reductase M Schober, C MacDermaid, AA Ollis, S Chang, D Khan, J Hosford, ... Nature Catalysis 2, 909-915, 2019 | 158 | 2019 |
| Expanding the toolbox of organic chemists: directed evolution of P450 monooxygenases as catalysts in regio-and stereoselective oxidative hydroxylation GD Roiban, MT Reetz Chemical communications 51 (12), 2208-2224, 2015 | 150 | 2015 |
| Achieving regio‐and enantioselectivity of P450‐catalyzed oxidative CH activation of small functionalized molecules by structure‐guided directed evolution R Agudo, GD Roiban, MT Reetz ChemBioChem 13 (10), 1465-1473, 2012 | 115 | 2012 |
| Efficient biocatalytic reductive aminations by extending the imine reductase toolbox GD Roiban, M Kern, Z Liu, J Hyslop, P Lyn Tey, MS Levine, LS Jordan, ... ChemCatChem, 2017 | 87 | 2017 |
| Cytochrome P450 Catalyzed Oxidative Hydroxylation of Achiral Organic Compounds with Simultaneous Creation of Two Chirality Centers in a Single C-H Activation Step GD Roiban, R Agudo, MT Reetz Angewandte Chemie International Edition 53, 8659–8663, 2014 | 76 | 2014 |
| Induced Axial Chirality in Biocatalytic Asymmetric Ketone Reduction R Agudo, GD Roiban, MT Reetz Journal of the American Chemical Society 135 (5), 1665–1668, 2012 | 74 | 2012 |
| Regioselective Orthopalladation of (Z)-2-Aryl-4-Arylidene-5(4H)-Oxazolones: Scope, Kinetico-Mechanistic, and Density Functional Theory Studies of the C–H … GD Roiban, E Serrano, T Soler, G Aullón, I Grosu, C Cativiela, M Martínez, ... Inorganic Chemistry 50 (17), 8132-8143, 2011 | 48 | 2011 |
| Biocatalytic route to chiral acyloins: P450-catalyzed regio-and enantioselective α-hydroxylation of ketones R Agudo, GD Roiban, R Lonsdale, A Ilie, MT Reetz The Journal of Organic Chemistry 80 (2), 950-956, 2015 | 45 | 2015 |
| CH-activating oxidative hydroxylation of 1-tetralones and related compounds with high regio-and stereoselectivity GD Roiban, R Agudo, A Ilie, R Lonsdale, MT Reetz Chemical communications 50 (92), 14310-14313, 2014 | 45 | 2014 |
| Glycine fluoromethylketones as SENP‐specific activity based probes C Dobrotă, D Fasci, ND Hădade, GD Roiban, C Pop, VM Meier, I Dumitru, ... ChemBioChem 13 (1), 80-84, 2012 | 45 | 2012 |
| Biocatalytic synthesis of chiral N‐functionalized amino acids JF Hyslop, SL Lovelock, PW Sutton, KK Brown, AJB Watson, GD Roiban Angewandte Chemie 130 (42), 14017-14020, 2018 | 39 | 2018 |
| A New Type of Stereoselectivity in Baeyer–Villiger Reactions: Access to E‐ and Z‐Olefins ZG Zhang, GD Roiban, JP Acevedo, I Polyak, MT Reetz Advanced Synthesis & Catalysis 355 (1), 99-106, 2013 | 37 | 2013 |
| Protein–inorganic array construction: design and synthesis of the building blocks ND Bogdan, M Matache, VM Meier, C Dobrotă, I Dumitru, GD Roiban, ... Chemistry–A European Journal 16 (7), 2170-2180, 2010 | 33 | 2010 |
| N-Alkyl-α-amino acids in Nature and their biocatalytic preparation JF Hyslop, SL Lovelock, AJB Watson, PW Sutton, GD Roiban Journal of biotechnology 293, 56-65, 2019 | 32 | 2019 |
| Palladium‐Catalysed Amination of Aryl‐ and Heteroaryl Halides Using tert‐Butyl Tetraisopropylphosphorodiamidite as an Easily Accessible and Air‐Stable Ligand GD Roiban, G Mehler, MT Reetz European Journal of Organic Chemistry 2014 (10), 2070-2076, 2014 | 32 | 2014 |
| Unexpected [2+ 2] C–C bond coupling due to photocycloaddition on orthopalladated (Z)-2-aryl-4-arylidene-5 (4 H)-oxazolones D Roiban, E Serrano, T Soler, I Grosu, C Cativiela, EP Urriolabeitia Chemical communications, 4681-4683, 2009 | 28 | 2009 |
| Stereo-and regioselectivity in the P450-catalyzed oxidative tandem difunctionalization of 1-methylcyclohexene GD Roiban, R Agudo, MT Reetz Tetrahedron 69 (26), 5306–5311, 2013 | 22 | 2013 |
| Identification and implementation of biocatalytic transformations in route discovery: synthesis of chiral 1, 3-substituted cyclohexanone building blocks T Hadi, A Dı́az-Rodrı́guez, D Khan, JP Morrison, JM Kaplan, KT Gallagher, ... Organic Process Research & Development 22 (7), 871-879, 2018 | 21 | 2018 |
| Enzyme promiscuity: using a P450 enzyme as a carbene transfer catalyst GD Roiban, MT Reetz Angewandte Chemie International Edition 21 (52), 5439-5440, 2013 | 21 | 2013 |
Ion GrosuProfessor of Organic Chemistry, Babeş-Bolyai UniversityVerified email at chem.ubbcluj.ro
