| Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis V Makarov, G Manina, K Mikusova, U Möllmann, O Ryabova, ... Science 324 (5928), 801-804, 2009 | 869 | 2009 |
| Dynamic persistence of antibiotic-stressed mycobacteria Y Wakamoto, N Dhar, R Chait, K Schneider, F Signorino-Gelo, S Leibler, ... Science 339 (6115), 91-95, 2013 | 618 | 2013 |
| Microbial phenotypic heterogeneity and antibiotic tolerance N Dhar, JD McKinney Current opinion in microbiology 10 (1), 30-38, 2007 | 429 | 2007 |
| Stress and host immunity amplify Mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms G Manina, N Dhar, JD McKinney Cell host & microbe 17 (1), 32-46, 2015 | 319 | 2015 |
| Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism A Koul, L Vranckx, N Dhar, HWH Göhlmann, E Özdemir, JM Neefs, ... Nature communications 5 (1), 3369, 2014 | 296 | 2014 |
| Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis J Neres, F Pojer, E Molteni, LR Chiarelli, N Dhar, S Boy-Röttger, S Buroni, ... Science translational medicine 4 (150), 150ra121-150ra121, 2012 | 217 | 2012 |
| Disruption of mptpB impairs the ability of Mycobacterium tuberculosis to survive in guinea pigs R Singh, V Rao, H Shakila, R Gupta, A Khera, N Dhar, A Singh, A Koul, ... Molecular microbiology 50 (3), 751-762, 2003 | 198 | 2003 |
| Single-cell dynamics of the chromosome replication and cell division cycles in mycobacteria I Santi, N Dhar, D Bousbaine, Y Wakamoto, JD McKinney Nature communications 4 (1), 2470, 2013 | 193 | 2013 |
| Simple Model for Testing Drugs against Nonreplicating Mycobacterium tuberculosis C Sala, N Dhar, RC Hartkoorn, M Zhang, YH Ha, P Schneider, ST Cole Antimicrobial agents and chemotherapy 54 (10), 4150-4158, 2010 | 158 | 2010 |
| Mycobacterium tuberculosis persistence mutants identified by screening in isoniazid-treated mice N Dhar, JD McKinney Proceedings of the National Academy of Sciences 107 (27), 12275-12280, 2010 | 140 | 2010 |
| Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG against tuberculosis M Ballester, C Nembrini, N Dhar, A De Titta, C De Piano, M Pasquier, ... Vaccine 29 (40), 6959-6966, 2011 | 135 | 2011 |
| 2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1 J Neres, RC Hartkoorn, LR Chiarelli, R Gadupudi, MR Pasca, G Mori, ... ACS chemical biology 10 (3), 705-714, 2015 | 133 | 2015 |
| Rapid cytolysis of Mycobacterium tuberculosis by faropenem, an orally bioavailable β-lactam antibiotic N Dhar, V Dubée, L Ballell, G Cuinet, JE Hugonnet, F Signorino-Gelo, ... Antimicrobial agents and chemotherapy 59 (2), 1308-1319, 2015 | 113 | 2015 |
| A lung-on-chip model of early Mycobacterium tuberculosis infection reveals an essential role for alveolar epithelial cells in controlling bacterial growth VV Thacker, N Dhar, K Sharma, R Barrile, K Karalis, JD McKinney Elife 9, e59961, 2020 | 110 | 2020 |
| Streptomycin-starved Mycobacterium tuberculosis 18b, a drug discovery tool for latent tuberculosis M Zhang, C Sala, RC Hartkoorn, N Dhar, A Mendoza-Losana, ST Cole Antimicrobial agents and chemotherapy 56 (11), 5782-5789, 2012 | 103 | 2012 |
| Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells J Vaubourgeix, G Lin, N Dhar, N Chenouard, X Jiang, H Botella, T Lupoli, ... Cell host & microbe 17 (2), 178-190, 2015 | 102 | 2015 |
| EspD is critical for the virulence-mediating ESX-1 secretion system in Mycobacterium tuberculosis JM Chen, S Boy-Röttger, N Dhar, N Sweeney, RS Buxton, F Pojer, ... Journal of bacteriology 194 (4), 884-893, 2012 | 102 | 2012 |
| Rapid endotheliitis and vascular damage characterize SARS‐CoV‐2 infection in a human lung‐on‐chip model VV Thacker, K Sharma, N Dhar, GF Mancini, J Sordet‐Dessimoz, ... EMBO reports 22 (6), e52744, 2021 | 98 | 2021 |
| 4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity M Naik, V Humnabadkar, SJ Tantry, M Panda, A Narayan, S Guptha, ... Journal of medicinal chemistry 57 (12), 5419-5434, 2014 | 97 | 2014 |
| Assessing the essentiality of the decaprenyl‐phospho‐d‐arabinofuranose pathway in Mycobacterium tuberculosis using conditional mutants GS Kolly, F Boldrin, C Sala, N Dhar, RC Hartkoorn, M Ventura, A Serafini, ... Molecular microbiology 92 (1), 194-211, 2014 | 97 | 2014 |
John McKinneyProfessor, Swiss Federal Institute of Technology Lausanne (EPFL)Verified email at epfl.ch
