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David MacPherson
David MacPherson
Verified email at fhcrc.org
Title
Cited by
Cited by
Year
Regulation of PTEN transcription by p53
V Stambolic, D MacPherson, D Sas, Y Lin, B Snow, Y Jang, S Benchimol, ...
Molecular cell 8 (2), 317-325, 2001
12162001
Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data
CM Rudin, JT Poirier, LA Byers, C Dive, A Dowlati, J George, JV Heymach, ...
Nature Reviews Cancer 19 (5), 289-297, 2019
8312019
High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/− mice
V Stambolic, MS Tsao, D Macpherson, A Suzuki, WB Chapman, TW Mak
Cancer research 60 (13), 3605-3611, 2000
4902000
Cell death attenuation byUsurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex
DM Rasper, JP Vaillancourt, S Hadano, VM Houtzager, I Seiden, ...
Cell Death & Differentiation 5 (4), 271-288, 1998
4391998
Cell type-specific effects of Rb deletion in the murine retina
D MacPherson, J Sage, T Kim, D Ho, ME McLaughlin, T Jacks
Genes & development 18 (14), 1681-1694, 2004
2692004
miR-17∼ 92 cooperates with RB pathway mutations to promote retinoblastoma
K Conkrite, M Sundby, S Mukai, JM Thomson, D Mu, SM Hammond, ...
Genes & development 25 (16), 1734-1745, 2011
2232011
Small cell lung cancer: can recent advances in biology and molecular biology be translated into improved outcomes?
PA Bunn Jr, JD Minna, A Augustyn, AF Gazdar, Y Ouadah, MA Krasnow, ...
Journal of Thoracic Oncology 11 (4), 453-474, 2016
2012016
Conditional Mutation of Rb Causes Cell Cycle Defects without Apoptosis in the Central Nervous System
D MacPherson, J Sage, D Crowley, A Trumpp, RT Bronson, T Jacks
Molecular and cellular biology 23 (3), 1044-1053, 2003
1862003
p53 Accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101
J Ruland, C Sirard, A Elia, D MacPherson, A Wakeham, L Li, ...
Proceedings of the National Academy of Sciences 98 (4), 1859-1864, 2001
1852001
Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition
A Augert, E Eastwood, AH Ibrahim, N Wu, E Grunblatt, R Basom, D Liggitt, ...
Science signaling 12 (567), eaau2922, 2019
1672019
Defective apoptosis and B‐cell lymphomas in mice with p53 point mutation at Ser 23
D MacPherson, J Kim, T Kim, BK Rhee, CTM van Oostrom, RA DiTullio Jr, ...
The EMBO journal 23 (18), 3689-3699, 2004
1522004
Lung cancer subtypes generate unique immune responses
SE Busch, ML Hanke, J Kargl, HE Metz, D MacPherson, AMG Houghton
The Journal of Immunology 197 (11), 4493-4503, 2016
1492016
New approaches to SCLC therapy: from the laboratory to the clinic
JT Poirier, J George, TK Owonikoko, A Berns, E Brambilla, LA Byers, ...
Journal of Thoracic Oncology 15 (4), 520-540, 2020
1452020
Crebbp Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition
D Jia, A Augert, DW Kim, E Eastwood, N Wu, AH Ibrahim, KB Kim, ...
Cancer discovery 8 (11), 1422-1437, 2018
1382018
PTEN is a potent suppressor of small cell lung cancer
M Cui, A Augert, M Rongione, K Conkrite, S Parazzoli, AY Nikitin, ...
Molecular Cancer Research 12 (5), 654-659, 2014
1232014
The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung
AF Gazdar, TK Savage, JE Johnson, A Berns, J Sage, RI Linnoila, ...
Journal of thoracic oncology 10 (4), 553-564, 2015
1132015
Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer
DW Kim, N Wu, YC Kim, PF Cheng, R Basom, D Kim, CT Dunn, AY Lee, ...
Genes & development 30 (11), 1289-1299, 2016
1022016
Murine bilateral retinoblastoma exhibiting rapid‐onset, metastatic progression and N‐myc gene amplification
D MacPherson, K Conkrite, M Tam, S Mukai, D Mu, T Jacks
The EMBO journal 26 (3), 784-794, 2007
872007
Small cell lung cancer exhibits frequent inactivating mutations in the histone methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance)
A Augert, Q Zhang, B Bates, M Cui, X Wang, G Wildey, A Dowlati, ...
Journal of Thoracic Oncology 12 (4), 704-713, 2017
852017
ARF is not required for apoptosis in Rb mutant mouse embryos
KY Tsai, D MacPherson, DA Rubinson, D Crowley, T Jacks
Current biology 12 (2), 159-163, 2002
712002
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