JAK2V617F but not CALR mutations confer increased molecular responses to interferon-α via JAK1/STAT1 activation J Czech, S Cordua, B Weinbergerova, J Baumeister, A Crepcia, L Han, ... Leukemia 33 (4), 995-1010, 2019 | 59 | 2019 |
Hypoxia-inducible factor 1 (HIF-1) is a new therapeutic target in JAK2V617F-positive myeloproliferative neoplasms J Baumeister, N Chatain, A Hubrich, T Maié, IG Costa, B Denecke, L Han, ... Leukemia 34 (4), 1062-1074, 2020 | 53 | 2020 |
Nrf2 is a central regulator of metabolic reprogramming of myeloid-derived suppressor cells in steady state and sepsis K Ohl, A Fragoulis, P Klemm, J Baumeister, W Klock, E Verjans, S Böll, ... Frontiers in immunology 9, 1552, 2018 | 51 | 2018 |
Progression of myeloproliferative neoplasms (MPN): diagnostic and therapeutic perspectives J Baumeister, N Chatain, AM Sofias, T Lammers, S Koschmieder Cells 10 (12), 3551, 2021 | 32 | 2021 |
Differential roles of STAT1 and STAT2 in the sensitivity of JAK2V617F-vs. BCR-ABL-positive cells to interferon alpha C Schubert, M Allhoff, S Tillmann, T Maié, IG Costa, DB Lipka, ... Journal of hematology & oncology 12, 1-16, 2019 | 24 | 2019 |
Type I but not type II calreticulin mutations activate the IRE1α/XBP1 pathway of the unfolded protein response to drive myeloproliferative neoplasms J Ibarra, YA Elbanna, K Kurylowicz, M Ciboddo, HS Greenbaum, ... Blood Cancer Discovery 3 (4), 298-315, 2022 | 14 | 2022 |
CALR frameshift mutations in MPN patient-derived iPSCs accelerate maturation of megakaryocytes K Olschok, L Han, MAS de Toledo, J Böhnke, M Graßhoff, IG Costa, ... Stem cell reports 16 (11), 2768-2783, 2021 | 14 | 2021 |
Early and late stage MPN patients show distinct gene expression profiles in CD34+ cells J Baumeister, T Maié, N Chatain, L Gan, B Weinbergerova, ... Annals of Hematology 100 (12), 2943-2956, 2021 | 13 | 2021 |
The unfolded protein response is a major driver of lcn2 expression in bcr–abl-and jak2v617f-positive mpn S Tillmann, K Olschok, SK Schröder, M Bütow, J Baumeister, M Kalmer, ... Cancers 13 (16), 4210, 2021 | 9 | 2021 |
Targeting cytokine-induced leukemic stem cell persistence in chronic myeloid leukemia by IKK2-inhibition M Bütow, FJ Testaquadra, J Baumeister, T Maié, N Chatain, T Jaquet, ... Haematologica 108 (4), 1179, 2023 | 4 | 2023 |
Clonogenic assays improve determination of variant allele frequency of driver mutations in myeloproliferative neoplasms M Kalmer, K Pannen, R Lemanzyk, C Wirths, J Baumeister, A Maurer, ... Annals of Hematology 101 (12), 2655-2663, 2022 | 4 | 2022 |
Engineering Mesoscopic 3D Tumor Models with a Self‐Organizing Vascularized Matrix F De Lorenzi, N Hansen, B Theek, R Daware, A Motta, S Breuel, R Nasehi, ... Advanced Materials 36 (5), 2303196, 2024 | 3 | 2024 |
Implication of Hypoxia-Inducible Factor-1 (HIF-1) As a New Therapeutic Target in JAK2V617F Positive Myeloproliferative Neoplasms (MPN) J Baumeister, N Chatain, A Hubrich, C Küstermann, S Sontag, K Seré, ... Blood 132, 4318, 2018 | 2 | 2018 |
Exploiting Synthetic Lethality between Germline BRCA1 Haploinsufficiency and PARP Inhibition in JAK2V617F-Positive Myeloproliferative Neoplasms M Bermes, MJ Rodriguez, MAS de Toledo, S Ernst, G Müller-Newen, ... International Journal of Molecular Sciences 24 (24), 17560, 2023 | 1 | 2023 |
Cellular aging is accelerated in the malignant clone of myeloproliferative neoplasms M Vieri, V Tharmapalan, M Kalmer, J Baumeister, M Nikolić, M Schnitker, ... Blood Cancer Journal 13 (1), 164, 2023 | 1 | 2023 |
Type 1 calreticulin mutations differentially activate the IRE1α-XBP1 pathway of the unfolded protein response to drive myeloproliferative neoplasms J Ibarra, Y Elbanna, K Kurylowicz, HS Greenbaum, M Evers, NS Arellano, ... Blood 138, 628, 2021 | 1 | 2021 |
Calreticulin and JAK2V617F driver mutations induce distinct mitotic defects in myeloproliferative neoplasms K Holl, N Chatain, S Krapp, J Baumeister, T Maié, S Schmitz, A Scheufen, ... Scientific Reports 14 (1), 2810, 2024 | | 2024 |
Engineering Mesoscopic 3D Tumor Models with a Self‐Organizing Vascularized Matrix (Adv. Mater. 5/2024) F De Lorenzi, N Hansen, B Theek, R Daware, A Motta, S Breuel, R Nasehi, ... Advanced Materials 36 (5), 2470037, 2024 | | 2024 |
ABL001 (asciminib) Efficiently Targets Transplantable BCR:: ABL1 Lymphoid Blast Crisis in the Scl-Tta-p210-BCR:: ABL1 Mouse Model N Chatain, J Baumeister, MS de Toledo, DWL Wong, S Gupta, K Pannen, ... Blood 142, 4193, 2023 | | 2023 |
Deciphering the complex clonal heterogeneity of polycythemia vera and the response to interferon alpha M Kalmer, M Grasshoff, T Maié, K Pannen, MAS Toledo, M Vieri, ... | | 2023 |