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Carl Ward
Carl Ward
Gladstone Institutes
Verified email at gladstone.ucsf.edu
Title
Cited by
Cited by
Year
Exogenous monounsaturated fatty acids promote a ferroptosis-resistant cell state
L Magtanong, PJ Ko, M To, JY Cao, GC Forcina, A Tarangelo, CC Ward, ...
Cell chemical biology 26 (3), 420-432. e9, 2019
6492019
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation
JN Spradlin, X Hu, CC Ward, SM Brittain, MD Jones, L Ou, M To, ...
Nature chemical biology 15 (7), 747-755, 2019
3122019
Covalent ligand screening uncovers a RNF4 E3 ligase recruiter for targeted protein degradation applications
CC Ward, JI Kleinman, SM Brittain, PS Lee, CYS Chung, K Kim, Y Petri, ...
ACS chemical biology 14 (11), 2430-2440, 2019
2352019
Discovery of human sORF-encoded polypeptides (SEPs) in cell lines and tissue
J Ma, CC Ward, I Jungreis, SA Slavoff, AG Schwaid, J Neveu, BA Budnik, ...
Journal of proteome research 13 (3), 1757-1765, 2014
1842014
Deubiquitinase-targeting chimeras for targeted protein stabilization
NJ Henning, L Boike, JN Spradlin, CC Ward, G Liu, E Zhang, BP Belcher, ...
Nature chemical biology 18 (4), 412-421, 2022
1552022
Covalent targeting of the vacuolar H+-ATPase activates autophagy via mTORC1 inhibition
CYS Chung, HR Shin, CA Berdan, B Ford, CC Ward, JA Olzmann, ...
Nature chemical biology 15 (8), 776-785, 2019
1362019
Activity-based protein profiling for mapping and pharmacologically interrogating proteome-wide ligandable hotspots
AM Roberts, CC Ward, DK Nomura
Current opinion in biotechnology 43, 25-33, 2017
1222017
NHS-esters as versatile reactivity-based probes for mapping proteome-wide ligandable hotspots
CC Ward, JI Kleinman, DK Nomura
ACS chemical biology 12 (6), 1478-1483, 2017
1212017
Covalent ligand discovery against druggable hotspots targeted by anti-cancer natural products
EA Grossman, CC Ward, JN Spradlin, LA Bateman, TR Huffman, ...
Cell chemical biology 24 (11), 1368-1376. e4, 2017
1072017
Ligandability of E3 ligases for targeted protein degradation applications
BP Belcher, CC Ward, DK Nomura
Biochemistry 62 (3), 588-600, 2021
572021
The regulation of glucose and lipid homeostasis via PLTP as a mediator of BAT–liver communication
CH Sponton, T Hosono, J Taura, MP Jedrychowski, T Yoneshiro, Q Wang, ...
EMBO reports 21 (9), e49828, 2020
312020
Screening a library of FDA-approved and bioactive compounds for antiviral activity against SARS-CoV-2
SB Biering, E Van Dis, E Wehri, LH Yamashiro, X Nguyenla, ...
ACS infectious diseases 7 (8), 2337-2351, 2021
252021
Formaldehyde regulates S-adenosylmethionine biosynthesis and one-carbon metabolism
VN Pham, KJ Bruemmer, JDW Toh, EJ Ge, L Tenney, CC Ward, ...
Science 382 (6670), eabp9201, 2023
112023
Base-editing mutagenesis maps alleles to tune human T cell functions
R Schmidt, CC Ward, R Dajani, Z Armour-Garb, M Ota, V Allain, ...
Nature 625 (7996), 805-812, 2024
102024
Discovery of Potent Pyrazoline‐Based Covalent SARS‐CoV‐2 Main Protease Inhibitors
P Moon, CM Zammit, Q Shao, D Dovala, L Boike, NJ Henning, M Knapp, ...
ChemBioChem 24 (11), e202300116, 2023
92023
Improving prime editing with an endogenous small RNA-binding protein
J Yan, P Oyler-Castrillo, P Ravisankar, CC Ward, S Levesque, Y Jing, ...
Nature, 1-9, 2024
22024
Methods and compounds for targeted autophagy
DK Nomura, R Zoncu, C Ward, SK Fung, CK Varma, B Fontaine
US Patent 11,666,661, 2023
2023
Discovery of Potent Pyrazoline-Based Covalent SARS-CoV-2 Main Protease Inhibitors (preprint)
P Moon, L Boike, D Dovala, N Henning, M Knapp, J Spradlin, C Ward, ...
2022
Covalent targeting of e3 ligases
J Spradlin, CC Ward, DK Nomura, M Schirle, JA Tallarico, J McKenna, ...
US Patent App. 17/282,277, 2021
2021
Compositions and methods for modulating ppp2r1a
DK Nomura, EA Moore, CC Ward, LA Bateman, TR Huffman, ...
US Patent App. 16/482,952, 2020
2020
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Articles 1–20