David Falck
David Falck
Center for Proteomics and Metabolomics, Leiden University Medical Center
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IgA subclasses have different effector functions associated with distinct glycosylation profiles
U Steffen, CA Koeleman, MV Sokolova, H Bang, A Kleyer, J Rech, ...
Nature communications 11 (1), 120, 2020
Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles—part 2: mass spectrometric methods
D Reusch, M Haberger, D Falck, B Peter, B Maier, J Gassner, M Hook, ...
MAbs 7 (4), 732-742, 2015
Linkage-specific sialic acid derivatization for MALDI-TOF-MS profiling of IgG glycopeptides
N de Haan, KR Reiding, M Haberger, D Reusch, D Falck, M Wuhrer
Analytical chemistry 87 (16), 8284-8291, 2015
Glycosylation of immunoglobulin G associates with clinical features of inflammatory bowel diseases
M Šimurina, N de Haan, F Vučković, NA Kennedy, J Štambuk, D Falck, ...
Gastroenterology 154 (5), 1320-1333. e10, 2018
FcγR binding and ADCC activity of human IgG allotypes
SW De Taeye, AEH Bentlage, MM Mebius, JI Meesters, ...
Frontiers in immunology 11, 740, 2020
LaCyTools: a targeted liquid chromatography–mass spectrometry data processing package for relative quantitation of glycopeptides
BC Jansen, D Falck, N de Haan, AL Hipgrave Ederveen, G Razdorov, ...
Journal of proteome research 15 (7), 2198-2210, 2016
MassyTools: a high-throughput targeted data processing tool for relative quantitation and quality control developed for glycomic and glycoproteomic MALDI-MS
BC Jansen, KR Reiding, A Bondt, AL Hipgrave Ederveen, M Palmblad, ...
Journal of proteome research 14 (12), 5088-5098, 2015
Highly sensitive CE-ESI-MS analysis of N-glycans from complex biological samples
GSM Lageveen-Kammeijer, N de Haan, P Mohaupt, S Wagt, M Filius, ...
Nature communications 10 (1), 2137, 2019
NIST interlaboratory study on glycosylation analysis of monoclonal antibodies: comparison of results from diverse analytical methods
MLA De Leoz, DL Duewer, A Fung, L Liu, HK Yau, O Potter, GO Staples, ...
Molecular & Cellular Proteomics 19 (1), 11-30, 2020
Mass spectrometry for glycosylation analysis of biopharmaceuticals
V Dotz, R Haselberg, A Shubhakar, RP Kozak, D Falck, Y Rombouts, ...
TrAC trends in analytical chemistry 73, 1-9, 2015
High-throughput analysis of IgG Fc glycopeptides by LC-MS
D Falck, BC Jansen, N de Haan, M Wuhrer
High-Throughput Glycomics and Glycoproteomics: Methods and Protocols, 31-47, 2017
Monitoring of immunoglobulin N- and O-glycosylation in health and disease
N de Haan, D Falck, M Wuhrer
Glycobiology 30 (4), 226-240, 2020
Dopant enriched nitrogen gas combined with sheathless capillary electrophoresis–electrospray ionization-mass spectrometry for improved sensitivity and repeatability in …
GSM Kammeijer, I Kohler, BC Jansen, PJ Hensbergen, OA Mayboroda, ...
Analytical chemistry 88 (11), 5849-5856, 2016
Pregnancy-associated serum N-glycome changes studied by high-throughput MALDI-TOF-MS
BC Jansen, A Bondt, KR Reiding, E Lonardi, CJ De Jong, D Falck, ...
Scientific reports 6 (1), 23296, 2016
Introduction to mass spectrometry, a tutorial
WMA Niessen, D Falck
Analyzing biomolecular interactions by mass spectrometry, 1-54, 2015
ACPA IgG galactosylation associates with disease activity in pregnant patients with rheumatoid arthritis
A Bondt, L Hafkenscheid, D Falck, TM Kuijper, Y Rombouts, JMW Hazes, ...
Annals of the rheumatic diseases 77 (8), 1130-1136, 2018
Glycoform-resolved FcɣRIIIa affinity chromatography–mass spectrometry
S Lippold, S Nicolardi, E Domínguez-Vega, AK Heidenreich, G Vidarsson, ...
MAbs 11 (7), 1191-1196, 2019
Glycoforms of immunoglobulin G based biopharmaceuticals are differentially cleaved by trypsin due to the glycoform influence on higher-order structure
D Falck, BC Jansen, R Plomp, D Reusch, M Haberger, M Wuhrer
Journal of proteome research 14 (9), 4019-4028, 2015
Simultaneous immunoglobulin A and G glycopeptide profiling for high-throughput applications
A Momčilović, N de Haan, AL Hipgrave Ederveen, A Bondt, ...
Analytical chemistry 92 (6), 4518-4526, 2020
Development of an online p38α mitogen-activated protein kinase binding assay and integration of LC–HR-MS
D Falck, JSB De Vlieger, WMA Niessen, J Kool, M Honing, M Giera, H Irth
Analytical and bioanalytical chemistry 398, 1771-1780, 2010
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