Transcription impacts the efficiency of mRNA translation via co-transcriptional N6-adenosine methylation B Slobodin, R Han, V Calderone, JAFO Vrielink, F Loayza-Puch, R Elkon, ... Cell 169 (2), 326-337. e12, 2017 | 415 | 2017 |
The poly (A)-binding protein nuclear 1 suppresses alternative cleavage and polyadenylation sites M Jenal*, R Elkon*, F Loayza-Puch*, G van Haaften, U Kühn, FM Menzies, ... Cell 149 (3), 538-553, 2012 | 388 | 2012 |
Tumour-specific proline vulnerability uncovered by differential ribosome codon reading F Loayza-Puch*, K Rooijers*, LCM Buil, J Zijlstra, JFO Vrielink, R Lopes, ... Nature 530 (7591), 490-494, 2016 | 234 | 2016 |
p53 induces transcriptional and translational programs to suppress cell proliferation and growth F Loayza-Puch, J Drost, K Rooijers, R Lopes, R Elkon, R Agami Genome biology 14, 1-12, 2013 | 133 | 2013 |
BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1 R Drost, KK Dhillon, H Van Der Gulden, I Van Der Heijden, I Brandsma, ... The Journal of clinical investigation 126 (8), 2903-2918, 2016 | 122 | 2016 |
Ribosome profiling reveals features of normal and disease-associated mitochondrial translation K Rooijers*, F Loayza-Puch*, LG Nijtmans, R Agami Nature communications 4 (1), 1-8, 2013 | 116 | 2013 |
Hypoxia and RAS-signaling pathways converge on, and cooperatively downregulate, the RECK tumor-suppressor protein through microRNAs F Loayza-Puch, Y Yoshida, T Matsuzaki, C Takahashi, H Kitayama, ... Oncogene 29 (18), 2638-2648, 2010 | 116 | 2010 |
Myc coordinates transcription and translation to enhance transformation and suppress invasiveness R Elkon*, F Loayza‐Puch*, G Korkmaz, R Lopes, PC Van Breugel, ... EMBO reports 16 (12), 1723-1736, 2015 | 52 | 2015 |
Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix EJ Kay, K Paterson, C Riera-Domingo, D Sumpton, JHM Däbritz, ... Nature metabolism 4 (6), 693-710, 2022 | 51 | 2022 |
Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells KR Kampen, L Fancello, T Girardi, G Rinaldi, M Planque, SO Sulima, ... Nature Communications 10 (1), 2542, 2019 | 51 | 2019 |
FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming IS Hansen, L Krabbendam, JH Bernink, F Loayza-Puch, W Hoepel, ... Nature communications 9 (1), 863, 2018 | 51 | 2018 |
LncRNA-OIS1 regulates DPP4 activation to modulate senescence induced by RAS L Li, PC Van Breugel, F Loayza-Puch, AP Ugalde, G Korkmaz, ... Nucleic acids research 46 (8), 4213-4227, 2018 | 46 | 2018 |
Proteomic patterns associated with response to breast cancer neoadjuvant treatment A Shenoy, N Belugali Nataraj, G Perry, F Loayza Puch, R Nagel, I Marin, ... Molecular systems biology 16 (9), e9443, 2020 | 43 | 2020 |
A fragment-like approach to PYCR1 inhibition K Milne, J Sun, EA Zaal, J Mowat, PHN Celie, A Fish, CR Berkers, ... Bioorganic & medicinal chemistry letters 29 (18), 2626-2631, 2019 | 36 | 2019 |
Exposure to arginine analog canavanine induces aberrant mitochondrial translation products, mitoribosome stalling, and instability of the mitochondrial proteome S Konovalova, T Hilander, F Loayza-Puch, K Rooijers, R Agami, ... The International Journal of Biochemistry & Cell Biology 65, 268-274, 2015 | 20 | 2015 |
3′ UTR-mediated gene silencing of the Mixed Lineage Leukemia (MLL) gene M Gomez-Benito, F Loayza-Puch, J Oude Vrielink, MD Odero, R Agami PLoS One 6 (10), e25449, 2011 | 16 | 2011 |
Using mitoribosomal profiling to investigate human mitochondrial translation F Gao, M Wesolowska, R Agami, K Rooijers, F Loayza-Puch, C Lawless, ... Wellcome Open Research 2, 2017 | 12 | 2017 |
Monitoring amino acid deficiencies in cancer F Loayza-Puch, R Agami Cell Cycle 15 (17), 2229-2230, 2016 | 12 | 2016 |
Alternative cleavage and polyadenylation generates downstream uncapped RNA isoforms with translation potential Y Malka, F Alkan, S Ju, PR Körner, A Pataskar, E Shulman, ... Molecular Cell 82 (20), 3840-3855. e8, 2022 | 9 | 2022 |
Lncing protein translation to metastasis F Loayza‐Puch, R Agami The EMBO Journal 32 (20), 2657-2658, 2013 | 9 | 2013 |