Current view on the functional regulation of the neuronal K+-Cl− cotransporter KCC2 I Medina, P Friedel, C Rivera, KT Kahle, N Kourdougli, P Uvarov, ... Frontiers in cellular neuroscience 8, 27, 2014 | 206 | 2014 |
A novel N-terminal isoform of the neuron-specific K-Cl cotransporter KCC2 P Uvarov, A Ludwig, M Markkanen, P Pruunsild, K Kaila, E Delpire, ... Journal of Biological Chemistry 282 (42), 30570-30576, 2007 | 180 | 2007 |
Early growth response 4 mediates BDNF induction of potassium chloride cotransporter 2 transcription A Ludwig, P Uvarov, S Soni, J Thomas-Crusells, MS Airaksinen, C Rivera Journal of Neuroscience 31 (2), 644-649, 2011 | 125 | 2011 |
Coexpression and heteromerization of two neuronal K-Cl cotransporter isoforms in neonatal brain P Uvarov, A Ludwig, M Markkanen, S Soni, CA Hubner, C Rivera, ... Journal of Biological Chemistry 284 (20), 13696-13704, 2009 | 100 | 2009 |
Upregulation of the neuron-specific K+/Cl− cotransporter expression by transcription factor early growth response 4 P Uvarov, A Ludwig, M Markkanen, C Rivera, MS Airaksinen Journal of Neuroscience 26 (52), 13463-13473, 2006 | 92 | 2006 |
Kainate receptors coexist in a functional complex with KCC2 and regulate chloride homeostasis in hippocampal neurons V Mahadevan, JC Pressey, BA Acton, P Uvarov, MY Huang, J Chevrier, ... Cell reports 7 (6), 1762-1770, 2014 | 84 | 2014 |
LRRTM3 regulates excitatory synapse development through alternative splicing and neurexin binding JW Um, TY Choi, H Kang, YS Cho, G Choii, P Uvarov, D Park, D Jeong, ... Cell reports 14 (4), 808-822, 2016 | 72 | 2016 |
Hyperpolarizing GABAergic transmission requires the KCC2 C-terminal ISO domain BA Acton, V Mahadevan, A Mercado, P Uvarov, Y Ding, J Pressey, ... Journal of Neuroscience 32 (25), 8746-8751, 2012 | 66 | 2012 |
The multifaceted roles of KCC2 in cortical development MA Virtanen, P Uvarov, M Mavrovic, JC Poncer, K Kaila Trends in neurosciences 44 (5), 378-392, 2021 | 64 | 2021 |
Distribution of neuronal KCC2a and KCC2b isoforms in mouse CNS M Markkanen, T Karhunen, O Llano, A Ludwig, C Rivera, P Uvarov, ... Journal of Comparative Neurology 522 (8), 1897-1914, 2014 | 60 | 2014 |
Vasopressin excites interneurons to suppress hippocampal network activity across a broad span of brain maturity at birth A Spoljaric, P Seja, I Spoljaric, MA Virtanen, J Lindfors, P Uvarov, ... Proceedings of the National Academy of Sciences 114 (50), E10819-E10828, 2017 | 58 | 2017 |
Native KCC2 interactome reveals PACSIN1 as a critical regulator of synaptic inhibition V Mahadevan, CS Khademullah, Z Dargaei, J Chevrier, P Uvarov, J Kwan, ... Elife 6, e28270, 2017 | 56 | 2017 |
Neuronal K+/Cl– co‐transporter (KCC2) transgenes lacking neurone restrictive silencer element recapitulate CNS neurone‐specific expression and developmental up … P Uvarov, P Pruunsild, T Timmusk, MS Airaksinen Journal of neurochemistry 95 (4), 1144-1155, 2005 | 56 | 2005 |
Neurturin evokes MAPK-dependent upregulation of Egr4 and KCC2 in developing neurons A Ludwig, P Uvarov, C Pellegrino, J Thomas-Crusells, S Schuchmann, ... Neural plasticity 2011, 2011 | 50 | 2011 |
NKCC1, an elusive molecular target in brain development: making sense of the existing data MA Virtanen, P Uvarov, CA Hübner, K Kaila Cells 9 (12), 2607, 2020 | 49 | 2020 |
A kainate receptor subunit promotes the recycling of the neuron-specific K+-Cl− co-transporter KCC2 in hippocampal neurons JC Pressey, V Mahadevan, CS Khademullah, Z Dargaei, J Chevrier, W Ye, ... Journal of Biological Chemistry 292 (15), 6190-6201, 2017 | 39 | 2017 |
Role of upstream stimulating factors in the transcriptional regulation of the neuron-specific K–Cl cotransporter KCC2 M Markkanen, P Uvarov, MS Airaksinen Brain research 1236, 8-15, 2008 | 36 | 2008 |
Up-and down-regulation of Helix command-specific 2 (HCS2) gene expression in the nervous system of terrestrial snail Helix lucorum PM Balaban, DA Poteryaev, IS Zakharov, P Uvarov, A Malyshev, ... Neuroscience 103 (2), 551-559, 2001 | 31 | 2001 |
Implications of the N-terminal heterogeneity for the neuronal K-Cl cotransporter KCC2 function M Markkanen, A Ludwig, S Khirug, E Pryazhnikov, S Soni, L Khiroug, ... Brain research 1675, 87-101, 2017 | 29 | 2017 |
Role of the K+-Cl–Cotransporter KCC2a Isoform in Mammalian Respiration at Birth CJ Dubois, L Cardoit, V Schwarz, M Markkanen, MS Airaksinen, P Uvarov, ... ENeuro 5 (5), 2018 | 18 | 2018 |