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Brian Tuch
Brian Tuch
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Cited by
Year
mRNA-Seq whole-transcriptome analysis of a single cell
F Tang, C Barbacioru, Y Wang, E Nordman, C Lee, N Xu, X Wang, ...
Nature methods 6 (5), 377-382, 2009
36112009
Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children
A Drilon, TW Laetsch, S Kummar, SG DuBois, UN Lassen, GD Demetri, ...
New England Journal of Medicine 378 (8), 731-739, 2018
24722018
The developmental transcriptome of Drosophila melanogaster
BR Graveley, AN Brooks, JW Carlson, MO Duff, JM Landolin, L Yang, ...
Nature 471 (7339), 473-479, 2011
16702011
Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution
LJ Holt, BB Tuch, J VillÚn, AD Johnson, SP Gygi, DO Morgan
Science 325 (5948), 1682-1686, 2009
10142009
A Recently Evolved Transcriptional Network Controls Biofilm Development in Candida albicans
CJ Nobile, EP Fox, JE Nett, TR Sorrells, QM Mitrovich, AD Hernday, ...
Cell 148 (1), 126-138, 2012
7522012
Larotrectinib for paediatric solid tumours harbouring NTRK gene fusions: phase 1 results from a multicentre, open-label, phase 1/2 study
TW Laetsch, SG DuBois, L Mascarenhas, B Turpin, N Federman, ...
The Lancet Oncology 19 (5), 705-714, 2018
5022018
An Oncogenic NTRK Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101
RC Doebele, LE Davis, A Vaishnavi, AT Le, A Estrada-Bernal, S Keysar, ...
Cancer discovery 5 (10), 1049-1057, 2015
410*2015
A next-generation TRK kinase inhibitor overcomes acquired resistance to prior TRK kinase inhibition in patients with TRK fusion–positive solid tumors
A Drilon, R Nagasubramanian, JF Blake, N Ku, BB Tuch, K Ebata, S Smith, ...
Cancer discovery 7 (9), 963-972, 2017
3822017
Selective RET kinase inhibition for patients with RET-altered cancers
V Subbiah, V Velcheti, BB Tuch, K Ebata, NL Busaidy, ME Cabanillas, ...
Annals of Oncology 29 (8), 1869-1876, 2018
3552018
An iron homeostasis regulatory circuit with reciprocal roles in Candida albicans commensalism and pathogenesis
C Chen, K Pande, SD French, BB Tuch, SM Noble
Cell host & microbe 10 (2), 118-135, 2011
3352011
Interlocking transcriptional feedback loops control white-opaque switching in Candida albicans
RE Zordan, MG Miller, DJ Galgoczy, BB Tuch, AD Johnson
PLoS biology 5 (10), e256, 2007
3312007
Evolution of alternative transcriptional circuits with identical logic
AE Tsong, BB Tuch, H Li, AD Johnson
Nature 443 (7110), 415-420, 2006
2992006
The evolution of combinatorial gene regulation in fungi
BB Tuch, DJ Galgoczy, AD Hernday, H Li, AD Johnson
PLoS Biology 6 (2), e38, 2008
2942008
RET solvent front mutations mediate acquired resistance to selective RET inhibition in RET-driven malignancies
BJ Solomon, L Tan, JJ Lin, SQ Wong, S Hollizeck, K Ebata, BB Tuch, ...
Journal of Thoracic Oncology 15 (4), 541-549, 2020
2142020
Evolution of eukaryotic transcription circuits
BB Tuch, H Li, AD Johnson
Science 319 (5871), 1797-1799, 2008
1832008
Resistance to TRK inhibition mediated by convergent MAPK pathway activation
E Cocco, AM Schram, A Kulick, S Misale, HH Won, R Yaeger, P Razavi, ...
Nature medicine 25 (9), 1422-1427, 2019
1772019
Tumor transcriptome sequencing reveals allelic expression imbalances associated with copy number alterations
BB Tuch, RR Laborde, X Xu, J Gu, CB Chung, CK Monighetti, SJ Stanley, ...
PloS one 5 (2), e9317, 2010
1662010
The transcriptomes of two heritable cell types illuminate the circuit governing their differentiation
BB Tuch, QM Mitrovich, OR Homann, AD Hernday, CK Monighetti, ...
PLoS genetics 6 (8), e1001070, 2010
1642010
Deterministic and stochastic allele specific gene expression in single mouse blastomeres
F Tang, C Barbacioru, E Nordman, S Bao, C Lee, X Wang, BB Tuch, ...
PloS one 6 (6), e21208, 2011
1502011
Larotrectinib in adult patients with solid tumours: a multi-centre, open-label, phase I dose-escalation study
DS Hong, TM Bauer, JJ Lee, A Dowlati, MS Brose, AF Farago, M Taylor, ...
Annals of Oncology 30 (2), 325-331, 2019
1382019
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