Oncogenic pathway signatures in human cancers as a guide to targeted therapies AH Bild, G Yao, JT Chang, Q Wang, A Potti, D Chasse, MB Joshi, ... Nature 439 (7074), 353-357, 2006 | 2359 | 2006 |
Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways ET Cirulli, BN Lasseigne, S Petrovski, PC Sapp, PA Dion, CS Leblond, ... Science 347 (6229), 1436-1441, 2015 | 1046 | 2015 |
Genic intolerance to functional variation and the interpretation of personal genomes S Petrovski, Q Wang, EL Heinzen, AS Allen, DB Goldstein PLoS genetics 9 (8), e1003709, 2013 | 1042 | 2013 |
High-dimensional sparse factor modeling: applications in gene expression genomics CM Carvalho, J Chang, JE Lucas, JR Nevins, Q Wang, M West Journal of the American Statistical Association 103 (484), 1438-1456, 2008 | 653 | 2008 |
Genome-wide analyses identify KIF5A as a novel ALS gene A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ... Neuron 97 (6), 1267-1288, 2018 | 650 | 2018 |
Whole-exome sequencing in the evaluation of fetal structural anomalies: a prospective cohort study S Petrovski, V Aggarwal, JL Giordano, M Stosic, K Wou, L Bier, E Spiegel, ... The Lancet 393 (10173), 758-767, 2019 | 538 | 2019 |
Plasma proteomic associations with genetics and health in the UK Biobank BB Sun, J Chiou, M Traylor, C Benner, YH Hsu, TG Richardson, ... Nature 622 (7982), 329-338, 2023 | 462* | 2023 |
A pathway-based classification of human breast cancer ML Gatza, JE Lucas, WT Barry, JW Kim, Q Wang, M D. Crawford, ... Proceedings of the National Academy of Sciences 107 (15), 6994-6999, 2010 | 396 | 2010 |
SSS: High-dimensional Bayesian regression model search C Hans, Q Wang, A Dobra, M West Bulletin of the International Society for Bayesian Analysis 24 (8-9), 21, 2007 | 358* | 2007 |
Rare variant contribution to human disease in 281,104 UK Biobank exomes Q Wang, RS Dhindsa, K Carss, AR Harper, A Nag, I Tachmazidou, ... Nature 597 (7877), 527-532, 2021 | 338 | 2021 |
Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank JD Szustakowski, S Balasubramanian, E Kvikstad, S Khalid, PG Bronson, ... Nature genetics 53 (7), 942-948, 2021 | 333 | 2021 |
Understanding GPU programming for statistical computation: Studies in massively parallel massive mixtures MA Suchard, Q Wang, C Chan, J Frelinger, A Cron, M West Journal of computational and graphical statistics 19 (2), 419-438, 2010 | 259 | 2010 |
An exome sequencing study to assess the role of rare genetic variation in pulmonary fibrosis S Petrovski, JL Todd, MT Durheim, Q Wang, JW Chien, FL Kelly, ... American journal of respiratory and critical care medicine 196 (1), 82-93, 2017 | 227 | 2017 |
Optimizing genomic medicine in epilepsy through a gene-customized approach to missense variant interpretation J Traynelis, M Silk, Q Wang, SF Berkovic, L Liu, DB Ascher, DJ Balding, ... Genome research 27 (10), 1715-1729, 2017 | 193 | 2017 |
Sparse statistical modelling in gene expression genomics J Lucas, C Carvalho, Q Wang, A Bild, JR Nevins, M West Bayesian inference for gene expression and proteomics 1 (1), 1644, 2006 | 180 | 2006 |
Ultra-rare genetic variation in common epilepsies: a case-control sequencing study AS Allen, ST Bellows, SF Berkovic, J Bridgers, R Burgess, G Cavalleri, ... The Lancet Neurology 16 (2), 135-143, 2017 | 176 | 2017 |
The intolerance of regulatory sequence to genetic variation predicts gene dosage sensitivity S Petrovski, AB Gussow, Q Wang, M Halvorsen, Y Han, WH Weir, ... PLoS genetics 11 (9), e1005492, 2015 | 149 | 2015 |
The intolerance to functional genetic variation of protein domains predicts the localization of pathogenic mutations within genes AB Gussow, S Petrovski, Q Wang, AS Allen, DB Goldstein Genome biology 17, 1-11, 2016 | 148 | 2016 |
Annotating pathogenic non-coding variants in genic regions S Gelfman, Q Wang, KM McSweeney, Z Ren, F La Carpia, M Halvorsen, ... Nature communications 8 (1), 236, 2017 | 147 | 2017 |
Image segmentation and dynamic lineage analysis in single‐cell fluorescence microscopy Q Wang, J Niemi, CM Tan, L You, M West Cytometry Part A: The Journal of the International Society for Advancement …, 2010 | 145 | 2010 |