Manuela Tosin
Manuela Tosin
Associate Professor, University of Warwick
Verified email at - Homepage
Cited by
Cited by
Synthesis of α-glucuronic acid and amide derivatives in the presence of a participating 2-acyl protecting group
M Tosin, PV Murphy
Organic Letters 4 (21), 3675-3678, 2002
Biosynthesis of the putative siderophore erythrochelin requires unprecedented crosstalk between separate nonribosomal peptide gene clusters
O Lazos, M Tosin, AL Slusarczyk, S Boakes, J Cortés, PJ Sidebottom, ...
Chemistry & biology 17 (2), 160-173, 2010
In vitro reconstruction of tetronate RK-682 biosynthesis
Y Sun, F Hahn, Y Demydchuk, J Chettle, M Tosin, H Osada, PF Leadlay
Nature chemical biology 6 (2), 99-101, 2010
Glycosidation Reactions of Silyl Ethers with Conformationally Inverted Donors Derived from Glucuronic Acid: Stereoselective Synthesis of Glycosides and 2‐Deoxyglycosides
M Poláková, N Pitt, M Tosin, PV Murphy
Angewandte Chemie 116 (19), 2572-2575, 2004
Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity
T Izoré, YT Candace Ho, JA Kaczmarski, A Gavriilidou, KH Chow, ...
Nature communications 12 (1), 2511, 2021
Glycosidation–Anomerisation Reactions of 6,1‐Anhydroglucopyranuronic Acid and Anomerisation of β‐D‐Glucopyranosiduronic Acids Promoted by SnCl4
C O'Brien, M Poláková, N Pitt, M Tosin, PV Murphy
Chemistry–A European Journal 13 (3), 902-909, 2007
Development of carbohydrate-based scaffolds for restricted presentation of recognition groups. Extension to divalent ligands and implications for the structure of dimerized …
PV Murphy, H Bradley, M Tosin, N Pitt, GM Fitzpatrick, WK Glass
The Journal of Organic Chemistry 68 (14), 5692-5704, 2003
Insights into protein-protein and enzyme-substrate interactions in modular polyketide synthases
L Tran, RW Broadhurst, M Tosin, A Cavalli, KJ Weissman
Chemistry & biology 17 (7), 705-716, 2010
Malonyl carba (dethia)‐and Malonyl oxa (dethia)‐coenzyme A as Tools for Trapping Polyketide Intermediates
M Tosin, D Spiteller, JB Spencer
ChemBioChem 10 (10), 1714-1723, 2009
Triggering the expression of a silent gene cluster from genetically intractable bacteria results in scleric acid discovery
F Alberti, DJ Leng, I Wilkening, L Song, M Tosin, C Corre
Chemical science 10 (2), 453-463, 2019
Insights into lasalocid A ring formation by chemical chain termination in vivo
M Tosin, L Smith, PF Leadlay
Angewandte Chemie International Edition 50 (50), 11930-11933, 2011
Chemical probes for the functionalization of polyketide intermediates
E Riva, I Wilkening, S Gazzola, WMA Li, L Smith, PF Leadlay, M Tosin
Angewandte Chemie 126 (44), 12138-12143, 2014
Insights into the stereospecificity of ketoreduction in a modular polyketide synthase
DH Kwan, M Tosin, N Schläger, F Schulz, PF Leadlay
Organic & biomolecular chemistry 9 (7), 2053-2056, 2011
Structural characterization of polyketides using high mass accuracy tandem mass spectrometry
RH Wills, M Tosin, PB O’Connor
Analytical chemistry 84 (20), 8863-8870, 2012
Synthetic Chain Terminators Off‐Load Intermediates from a Type I Polyketide Synthase
M Tosin, L Betancor, E Stephens, WM Ariel Li, JB Spencer, PF Leadlay
ChemBioChem 11 (4), 539-546, 2010
Insights into 6‐Methylsalicylic Acid Bio‐assembly by Using Chemical Probes
JS Parascandolo, J Havemann, HK Potter, F Huang, E Riva, J Connolly, ...
Angewandte Chemie 128 (10), 3524-3528, 2016
In vivo trapping of polyketide intermediates from an assembly line synthase using malonyl carba (dethia)-N-acetyl cysteamines
M Tosin, Y Demydchuk, JS Parascandolo, CB Per, FJ Leeper, PF Leadlay
Chemical communications 47 (12), 3460-3462, 2011
A genomics-led approach to deciphering the mechanism of thiotetronate antibiotic biosynthesis
W Tao, ME Yurkovich, S Wen, KE Lebe, M Samborskyy, Y Liu, A Yang, ...
Chemical Science 7 (1), 376-385, 2016
Phenylenediamine-based bivalent glycocyclophanes: synthesis and analysis of the influence of scaffold rigidity and ligand spacing on lectin binding in cell systems with …
S André, T Velasco-Torrijos, R Leyden, S Gouin, M Tosin, PV Murphy, ...
Organic & biomolecular chemistry 7 (22), 4715-4725, 2009
Synthesis of structurally defined scaffolds for bivalent ligand display based on glucuronic acid anilides. The degree of tertiary amide isomerism and folding depends on the …
M Tosin, PV Murphy
The Journal of Organic Chemistry 70 (10), 4107-4117, 2005
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