Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo F Debacq-Chainiaux, JD Erusalimsky, J Campisi, O Toussaint Nature protocols 4 (12), 1798-1806, 2009 | 1669 | 2009 |
Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-β1 signaling pathway F Debacq-Chainiaux, C Borlon, T Pascal, V Royer, F Eliaers, N Ninane, ... Journal of cell science 118 (4), 743-758, 2005 | 310 | 2005 |
Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins R Mitchell, B Mellows, J Sheard, M Antonioli, O Kretz, D Chambers, ... Stem cell research & therapy 10, 1-19, 2019 | 170 | 2019 |
UV, stress and aging F Debacq-Chainiaux, C Leduc, A Verbeke, O Toussaint Dermato-endocrinology 4 (3), 236-240, 2012 | 163 | 2012 |
Replicative aging down‐regulates the myogenic regulatory factors in human myoblasts A Bigot, V Jacquemin, F Debacq‐Chainiaux, GS Butler‐Browne, ... Biology of the Cell 100 (3), 189-199, 2008 | 161 | 2008 |
Serum N-glycan profile shift during human ageing V Vanhooren, S Dewaele, C Libert, S Engelborghs, PP De Deyn, ... Experimental gerontology 45 (10), 738-743, 2010 | 135 | 2010 |
Stress-induced premature senescence. Essence of life, evolution, stress, and aging. O Toussain, P Dumont, JF Dierick, T Pascal, C Frippiat, F Chainiaux, ... Annals of the New York Academy of Sciences 908, 2000 | 130 | 2000 |
Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays T Pascal, F Debacq-Chainiaux, A Chrétien, C Bastin, AF Dabée, ... FEBS letters 579 (17), 3651-3659, 2005 | 121 | 2005 |
UVB-induced premature senescence of human diploid skin fibroblasts F Chainiaux, JP Magalhaes, F Eliaers, J Remacle, O Toussaint The international journal of biochemistry & cell biology 34 (11), 1331-1339, 2002 | 115 | 2002 |
Stress-induced premature senescence in BJ and hTERT-BJ1 human foreskin fibroblasts JP De Magalhães, F Chainiaux, J Remacle, O Toussaint FEBS letters 523 (1-3), 157-162, 2002 | 112 | 2002 |
Overexpression of apolipoprotein J in human fibroblasts protects against cytotoxicity and premature senescence induced by ethanol and tert-butylhydroperoxide P Dumont, F Chainiaux, F Eliaers, C Petropoulou, J Remacle, ... Cell stress & chaperones 7 (1), 23, 2002 | 108 | 2002 |
Stress-Induced Premature Senescence or Stress-Induced Senescence-Like Phenotype: One In Vivo Reality, Two Possible Definitions? O Toussaint, P Dumont, J Remacle, JF Dierick, T Pascal, C Frippiat, ... The Scientific World JOURNAL 2, 230-247, 2002 | 105 | 2002 |
From the Hayflick mosaic to the mosaics of ageing.: Role of stress-induced premature senescence in human ageing O Toussaint, J Remacle, JF Dierick, T Pascal, C Frippiat, S Zdanov, ... The international journal of biochemistry & cell biology 34 (11), 1415-1429, 2002 | 103 | 2002 |
Gene expression and regulation in H2O2-induced premature senescence of human foreskin fibroblasts expressing or not telomerase JP De Magalhães, F Chainiaux, F De Longueville, V Mainfroid, V Migeot, ... Experimental gerontology 39 (9), 1379-1389, 2004 | 93 | 2004 |
The impact of cellular senescence in skin ageing: A notion of mosaic and therapeutic strategies M Toutfaire, E Bauwens, F Debacq-Chainiaux Biochemical pharmacology 142, 1-12, 2017 | 91 | 2017 |
Air pollution and the fetal origin of disease: a systematic review of the molecular signatures of air pollution exposure in human placenta LJ Luyten, ND Saenen, BG Janssen, K Vrijens, M Plusquin, HA Roels, ... Environmental Research 166, 310-323, 2018 | 90 | 2018 |
p38MAPK in the Senescence of Human and Murine Fibroblasts F Debacq-Chainiaux, E Boilan, JD Le Moutier, G Weemaels, O Toussaint Protein Metabolism and Homeostasis in Aging, 126-137, 2010 | 83 | 2010 |
Prematurely senescent ARPE-19 cells display features of age-related macular degeneration AL Glotin, F Debacq-Chainiaux, JY Brossas, AM Faussat, J Tréton, ... Free Radical Biology and Medicine 44 (7), 1348-1361, 2008 | 80 | 2008 |
Normal or stress-induced fibroblast senescence involves COX-2 activity S Zdanov, D Bernard, F Debacq-Chainiaux, S Martien, K Gosselin, ... Experimental cell research 313 (14), 3046-3056, 2007 | 77 | 2007 |
Screening of senescence-associated genes with specific DNA array reveals the role of IGFBP-3 in premature senescence of human diploid fibroblasts F Debacq-Chainiaux, T Pascal, E Boilan, C Bastin, E Bauwens, ... Free Radical Biology and Medicine 44 (10), 1817-1832, 2008 | 65 | 2008 |