Methods for reliability and uncertainty assessment and for applicability evaluations of classification-and regression-based QSARs. L Eriksson, J Jaworska, AP Worth, MTD Cronin, RM McDowell, ... Environmental health perspectives 111 (10), 1361-1375, 2003 | 1327 | 2003 |
Current status of methods for defining the applicability domain of (quantitative) structure-activity relationships: The report and recommendations of ecvam workshop 52 TI Netzeva, AP Worth, T Aldenberg, R Benigni, MTD Cronin, P Gramatica, ... Alternatives to Laboratory Animals 33 (2), 155-173, 2005 | 766 | 2005 |
Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010 S Adler, D Basketter, S Creton, O Pelkonen, J Van Benthem, V Zuang, ... Archives of toxicology 85 (5), 367-485, 2011 | 561 | 2011 |
A modular approach to the ECVAM principles on test validity T Hartung, S Bremer, S Casati, S Coecke, R Corvi, S Fortaner, L Gribaldo, ... Alternatives to Laboratory Animals 32 (5), 467-472, 2004 | 346 | 2004 |
An evaluation of the implementation of the Cramer classification scheme in the Toxtree software G Patlewicz, N Jeliazkova, RJ Safford, AP Worth, B Aleksiev SAR and QSAR in Environmental Research 19 (5-6), 495-524, 2008 | 322 | 2008 |
Use of QSARs in international decision-making frameworks to predict health effects of chemical substances. MTD Cronin, JS Jaworska, JD Walker, MHI Comber, CD Watts, AP Worth Environmental health perspectives 111 (10), 1391-1401, 2003 | 308 | 2003 |
A theoretical framework for predicting the oxidative stress potential of oxide nanoparticles E Burello, AP Worth Nanotoxicology 5 (2), 228-235, 2011 | 298 | 2011 |
Applying adverse outcome pathways (AOPs) to support integrated approaches to testing and assessment (IATA) KE Tollefsen, S Scholz, MT Cronin, SW Edwards, J de Knecht, K Crofton, ... Regulatory Toxicology and Pharmacology 70 (3), 629-640, 2014 | 286 | 2014 |
CERAPP: collaborative estrogen receptor activity prediction project K Mansouri, A Abdelaziz, A Rybacka, A Roncaglioni, A Tropsha, A Varnek, ... Environmental health perspectives 124 (7), 1023-1033, 2016 | 237 | 2016 |
Use of QSARs in international decision-making frameworks to predict ecologic effects and environmental fate of chemical substances. MTD Cronin, JD Walker, JS Jaworska, MHI Comber, CD Watts, AP Worth Environmental Health Perspectives 111 (10), 1376-1390, 2003 | 228 | 2003 |
The ECVAM international validation study on in vitro tests for acute skin irritation: report on the validity of the EPISKIN and EpiDerm assays and on the Skin Integrity … H Spielmann, S Hoffmann, M Liebsch, P Botham, JH Fentem, C Eskes, ... Alternatives to Laboratory Animals 35 (6), 559-601, 2007 | 215 | 2007 |
Metabolism: A Bottleneck in In Vitro Toxicological Test Development: The Report and Recommendations of ECVAM Workshop 54 S Coecke, H Ahr, BJ Blaauboer, S Bremer, S Casati, J Castell, R Combes, ... Alternatives to Laboratory Animals 34 (1), 49-84, 2006 | 185 | 2006 |
Applying quantitative structure–activity relationship approaches to nanotoxicology: current status and future potential DA Winkler, E Mombelli, A Pietroiusti, L Tran, A Worth, B Fadeel, ... Toxicology 313 (1), 15-23, 2013 | 178 | 2013 |
Regulatory assessment of chemical mixtures: requirements, current approaches and future perspectives A Kienzler, SK Bopp, S van der Linden, E Berggren, A Worth Regulatory Toxicology and Pharmacology 80, 321-334, 2016 | 170 | 2016 |
Alternative (non-animal) methods for chemicals testing: current status and future prospects a report prepared by ECVAM and the ECVAM Working Group on Chemicals A Worth, M Balls ATLA-NOTTINGHAM- 30, 2002 | 157 | 2002 |
The role of the European Chemicals Bureau in promoting the regulatory use of (Q) SAR methods AP Worth, A Bassan, J De Bruijn, A Gallegos Saliner, T Netzeva, M Pavan, ... SAR and QSAR in Environmental Research 18 (1-2), 111-125, 2007 | 153 | 2007 |
The Development and Validation of Expert Systems for Predicting Toxicity: The Report and Recommendations of an ECVAM/ECB Workshop (ECVAM Workshop 24), JC Dearden, MD Barratt, R Benigni, DW Bristol, RD Combes, MTD Cronin, ... Alternatives to laboratory animals 25 (3), 223-251, 1997 | 151 | 1997 |
QSAR modeling of nanomaterials E Burello, AP Worth Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 3 (3 …, 2011 | 144 | 2011 |
The Registry of Cytotoxicity: Toxicity Testing in Cell Cultures to Predict Acute Toxicity (LD50) and to Reduce Testing in Animals W Halle, M Halder, A Worth, E Genschow Alternatives to Laboratory Animals 31 (2), 89-89, 2003 | 140 | 2003 |
The use of discriminant analysis, logistic regression and classification tree analysis in the development of classification models for human health effects AP Worth, MTD Cronin Journal of Molecular Structure: THEOCHEM 622 (1-2), 97-111, 2003 | 134 | 2003 |