Christian Frezza
Christian Frezza
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Cited by
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
GM Tannahill, AM Curtis, J Adamik, EM Palsson-McDermott, ...
Nature 496 (7444), 238-242, 2013
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
ET Chouchani, VR Pell, E Gaude, D Aksentijević, SY Sundier, EL Robb, ...
Nature 515 (7527), 431-435, 2014
OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion
C Frezza, S Cipolat, OM De Brito, M Micaroni, GV Beznoussenko, ...
Cell 126 (1), 177-189, 2006
Succinate dehydrogenase supports metabolic repurposing of mitochondria to drive inflammatory macrophages
EL Mills, B Kelly, A Logan, ASH Costa, M Varma, CE Bryant, ...
Cell 167 (2), 457-470. e13, 2016
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
EL Mills, DG Ryan, HA Prag, D Dikovskaya, D Menon, Z Zaslona, ...
Nature 556 (7699), 113-117, 2018
Organelle isolation: functional mitochondria from mouse liver, muscle and cultured filroblasts
C Frezza, S Cipolat, L Scorrano
Nature protocols 2 (2), 287-295, 2007
Mitochondrial cristae shape determines respiratory chain supercomplexes assembly and respiratory efficiency
S Cogliati, C Frezza, ME Soriano, T Varanita, R Quintana-Cabrera, ...
Cell 155 (1), 160-171, 2013
Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling
S Cipolat, T Rudka, D Hartmann, V Costa, L Serneels, K Craessaerts, ...
Cell 126 (1), 163-175, 2006
A unifying mechanism for mitochondrial superoxide production during ischemia-reperfusion injury
ET Chouchani, VR Pell, AM James, LM Work, K Saeb-Parsy, C Frezza, ...
Cell metabolism 23 (2), 254-263, 2016
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
B Chaneton, P Hillmann, L Zheng, ACL Martin, ODK Maddocks, ...
Nature 491 (7424), 458-462, 2012
A roadmap for interpreting 13C metabolite labeling patterns from cells
JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, ...
Current opinion in biotechnology 34, 189-201, 2015
Predicting selective drug targets in cancer through metabolic networks
O Folger, L Jerby, C Frezza, E Gottlieb, E Ruppin, T Shlomi
Molecular systems biology 7 (1), 501, 2011
Serine is an essential metabolite for effector T cell expansion
EH Ma, G Bantug, T Griss, S Condotta, RM Johnson, B Samborska, ...
Cell metabolism 25 (2), 345-357, 2017
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase
C Frezza, L Zheng, O Folger, KN Rajagopalan, ED MacKenzie, L Jerby, ...
Nature 477 (7363), 225-228, 2011
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
M Sciacovelli, E Gonçalves, TI Johnson, VR Zecchini, ASH Da Costa, ...
Nature 537 (7621), 544-547, 2016
Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function
VA Morais, P Verstreken, A Roethig, J Smet, A Snellinx, M Vanbrabant, ...
EMBO molecular medicine 1 (2), 99-111, 2009
Mitochondria in cancer: not just innocent bystanders
C Frezza, E Gottlieb
Seminars in cancer biology 19 (1), 4-11, 2009
Coupling Krebs cycle metabolites to signalling in immunity and cancer
DG Ryan, MP Murphy, C Frezza, HA Prag, ET Chouchani, LA O’Neill, ...
Nature metabolism 1 (1), 16-33, 2019
Tissue-specific and convergent metabolic transformation of cancer correlates with metastatic potential and patient survival
E Gaude, C Frezza
Nature communications 7 (1), 13041, 2016
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