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Sara Salerno
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Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia
CC Smith, Q Wang, CS Chin, S Salerno, LE Damon, MJ Levis, AE Perl, ...
Nature 485 (7397), 260-263, 2012
8412012
Activity of ponatinib against clinically-relevant AC220-resistant kinase domain mutants of FLT3-ITD
CC Smith, EA Lasater, X Zhu, KC Lin, WK Stewart, LE Damon, S Salerno, ...
Blood, The Journal of the American Society of Hematology 121 (16), 3165-3171, 2013
1572013
Activation state-dependent binding of small molecule kinase inhibitors: structural insights from biochemistry
LM Wodicka, P Ciceri, MI Davis, JP Hunt, M Floyd, S Salerno, XH Hua, ...
Chemistry & biology 17 (11), 1241-1249, 2010
1322010
Clinical pharmacology studies in critically ill children
N Thakkar, S Salerno, CP Hornik, D Gonzalez
Pharmaceutical research 34, 7-24, 2017
582017
Association between nephrotoxic drug combinations and acute kidney injury in the neonatal intensive care unit
SN Salerno, Y Liao, W Jackson, RG Greenberg, CJ McKinzie, ...
The Journal of pediatrics 228, 213-219, 2021
412021
Pediatric drug-drug interaction studies: barriers and opportunities
SN Salerno, GJ Burckart, SM Huang, D Gonzalez
Clinical pharmacology and therapeutics 105 (5), 1067, 2019
372019
Physiologically‐based pharmacokinetic modeling characterizes the CYP3A‐mediated drug‐drug interaction between fluconazole and sildenafil in infants
SN Salerno, A Edginton, JG Gerhart, MM Laughon, N Ambalavanan, ...
Clinical Pharmacology & Therapeutics 109 (1), 253-262, 2021
282021
Physiologically‐based pharmacokinetic modeling of fluconazole using plasma and cerebrospinal fluid samples from preterm and term infants
JG Gerhart, KM Watt, A Edginton, KC Wade, SN Salerno, DK Benjamin Jr, ...
CPT: Pharmacometrics & Systems Pharmacology 8 (7), 500-510, 2019
152019
Use of Population Pharmacokinetics and Electronic Health Records to Assess Piperacillin–Tazobactam Safety in Infants
S Salerno, CP Hornik, M Cohen-Wolkowiez, PB Smith, LC Ku, MS Kelly, ...
The Pediatric infectious disease journal 36 (9), 855-859, 2017
142017
Development of an adult physiologically based pharmacokinetic model of solithromycin in plasma and epithelial lining fluid
SN Salerno, A Edginton, M Cohen‐Wolkowiez, CP Hornik, KM Watt, ...
CPT: Pharmacometrics & Systems Pharmacology 6 (12), 814-822, 2017
132017
Pharmacokinetics of Ceftaroline in a Preterm Infant With Methicillin-Resistant Staphylococcus Aureus Pneumonia
SN Salerno, J Bernhardt, M Laughon, R Jhaveri, M Massaro, D Gonzalez
Journal of the Pediatric Infectious Diseases Society 7 (4), 342-345, 2018
92018
Constitutively activating mutations at the FLT3 activation loop residue D835 are associated with clinical resistance to AC220
CC Smith, J Chin, E Lasater, AL Paguirigan, K Lin, W Stewart, S Salerno, ...
Blood 120 (21), 674, 2012
72012
Validation of FLT3-ITD as a therapeutic target in human acute myeloid leukemia
CC Smith, J Chin, Q Wang, S Salerno, LE Damon, JP Hunt, MJ Levis, ...
Blood 118 (21), 937, 2011
62011
Best Pharmaceuticals for Children Act–Pediatric Trials Network Steering Committee. Use of population pharmacokinetics and electronic health records to assess piperacillin …
S Salerno, CP Hornik, M Cohen-Wolkowiez, PB Smith, LC Ku, MS Kelly, ...
Pediatr Infect Dis J 36 (9), 855-859, 2017
52017
Activity of allosteric, switch-pocket, ABL/FLT3 kinase inhibitor DCC2036 against cultured and primary aml progenitors with FLT-ITD or FLT3 kinase domain mutations
W Fiskus, CC Smith, J Smith, SC Wise, E Lasater, LE Damon, S Salerno, ...
Blood 118 (21), 2611, 2011
52011
Leveraging physiologically based pharmacokinetic modeling and experimental data to guide dosing modification of CYP3A-mediated drug-drug interactions in the pediatric population
SN Salerno, FO Carreño, AN Edginton, M Cohen-Wolkowiez, D Gonzalez
Drug Metabolism and Disposition 49 (9), 844-855, 2021
42021
Leveraging physiologically based pharmacokinetic modeling to optimize dosing for lopinavir/ritonavir with rifampin in pediatric patients
SN Salerno, EV Capparelli, H McIlleron, JG Gerhart, JB Dumond, ...
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 43 (7 …, 2023
32023
Physiologically‐based pharmacokinetic modeling of immunoglobulin and antibody coadministration in patients with primary human immunodeficiency
SN Salerno, R Deng, T Kakkar
CPT: Pharmacometrics & Systems Pharmacology 11 (10), 1316-1327, 2022
32022
Single molecule real time (SMRT™) sequencing sensitively detects polyclonal and compound BCR-ABL in patients who relapse on kinase inhibitor therapy
CC Smith, M Brown, J Chin, C Kasap, S Salerno, LE Damon, K Travers, ...
Blood 118 (21), 3752, 2011
32011
Analysis of in vitro activity of the clinically-active ABL/FLT3 inhibitor Ponatinib (AP24534) against AC220-resistant FLT3-ITD mutants
CC Smith, LE Damon, X Zhu, S Salerno, N Shah
Blood 118 (21), 930, 2011
22011
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