Mapping cis- and trans-regulatory effects across multiple tissues in twins E Grundberg, KS Small, ÅK Hedman, AC Nica, A Buil, S Keildson, JT Bell, ... Nature genetics 44 (10), 1084-1089, 2012 | 884 | 2012 |
DNA methylation and body-mass index: a genome-wide analysis KJ Dick, CP Nelson, L Tsaprouni, JK Sandling, D Aïssi, S Wahl, E Meduri, ... The Lancet 383 (9933), 1990-1998, 2014 | 859 | 2014 |
Histone deacetylase 2–mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression K Ito, S Yamamura, S Essilfie-Quaye, B Cosio, M Ito, PJ Barnes, ... The Journal of experimental medicine 203 (1), 7-13, 2006 | 803 | 2006 |
Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages BG Cosio, L Tsaprouni, K Ito, E Jazrawi, IM Adcock, PJ Barnes The Journal of experimental medicine 200 (5), 689-695, 2004 | 574 | 2004 |
Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements E Grundberg, E Meduri, JK Sandling, ÅK Hedman, S Keildson, A Buil, ... The American Journal of Human Genetics 93 (5), 876-890, 2013 | 380 | 2013 |
Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation LG Tsaprouni, TP Yang, J Bell, KJ Dick, S Kanoni, J Nisbet, A Viñuela, ... Epigenetics 9 (10), 1382-1396, 2014 | 366 | 2014 |
Metabolomic markers reveal novel pathways of ageing and early development in human populations C Menni, G Kastenmüller, AK Petersen, JT Bell, M Psatha, PC Tsai, ... International journal of epidemiology 42 (4), 1111-1119, 2013 | 258 | 2013 |
Epigenetic regulation of airway inflammation IM Adcock, L Tsaprouni, P Bhavsar, K Ito Current opinion in immunology 19 (6), 694-700, 2007 | 255 | 2007 |
Unbalanced oxidant-induced DNA damage and repair in COPD: a link towards lung cancer G Caramori, IM Adcock, P Casolari, K Ito, E Jazrawi, L Tsaprouni, G Villetti, ... Thorax 66 (6), 521-527, 2011 | 200 | 2011 |
Glucocorticoid-mediated transrepression is regulated by histone acetylation and DNA methylation M Kagoshima, T Wilcke, K Ito, L Tsaprouni, PJ Barnes, N Punchard, ... European journal of pharmacology 429 (1-3), 327-334, 2001 | 121 | 2001 |
Redox regulation of histone deacetylases and glucocorticoid-mediated inhibition of the inflammatory response IM Adcock, B Cosio, L Tsaprouni, PJ Barnes, K Ito Antioxidants & redox signaling 7 (1-2), 144-152, 2005 | 110 | 2005 |
Differential patterns of histone acetylation in inflammatory bowel diseases LG Tsaprouni, K Ito, JJ Powell, IM Adcock, N Punchard Journal of Inflammation 8, 1-12, 2011 | 99 | 2011 |
Epigenetics in health and disease: heralding the EWAS era TM Murphy, J Mill The Lancet 383 (9933), 1952-1954, 2014 | 94 | 2014 |
Suppression of lipopolysaccharide-and tumour necrosis factor-α-induced interleukin (IL)-8 expression by glucocorticoids involves changes in IL-8 promoter acetylation LG Tsaprouni, K Ito, IM Adcock, N Punchard Clinical & Experimental Immunology 150 (1), 151-157, 2007 | 47 | 2007 |
Overview of the interactive task in BioCreative V Q Wang, S S. Abdul, L Almeida, S Ananiadou, YI Balderas-Martínez, ... Database 2016, baw119, 2016 | 38 | 2016 |
The association of the ACTN3 R577X and ACE I/D polymorphisms with athlete status in football: a systematic review and meta-analysis ABT McAuley, DC Hughes, LG Tsaprouni, I Varley, B Suraci, TR Roos, ... Journal of sports sciences 39 (2), 200-211, 2021 | 36 | 2021 |
Adult onset asthma and interaction between genes and active tobacco smoking: the GABRIEL consortium JM Vonk, S Scholtens, DS Postma, MF Moffatt, D Jarvis, A Ramasamy, ... PLoS One 12 (3), e0172716, 2017 | 33 | 2017 |
Genetic association research in football: A systematic review ABT McAuley, DC Hughes, LG Tsaprouni, I Varley, B Suraci, TR Roos, ... European journal of sport science 21 (5), 714-752, 2021 | 28 | 2021 |
Triamcinolone Acetonide and Dexamethasome Suppress TNF‐α‐Induced Histone H4 Acetylation on Lysine Residues 8 and 12 in Mononuclear Cells LG Tsaprouni, K Ito, N Punchard, IM Adcock Annals of the New York Academy of Sciences 973 (1), 481-483, 2002 | 24 | 2002 |
Translational biomarkers in the era of precision medicine L Bravo-Merodio, A Acharjee, D Russ, V Bisht, JA Williams, LG Tsaprouni, ... Advances in clinical chemistry 102, 191-232, 2021 | 23 | 2021 |