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Steven A Titus
Steven A Titus
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Year
SNARE-complex disassembly by NSF follows synaptic-vesicle fusion
JT Littleton, RJO Barnard, SA Titus, J Slind, ER Chapman, B Ganetzky
Proceedings of the National Academy of Sciences 98 (21), 12233-12238, 2001
1732001
Concerted assembly and cloning of multiple DNA segments using in vitro site-specific recombination: functional analysis of multi-segment expression clones
DL Cheo, SA Titus, DRN Byrd, JL Hartley, GF Temple, MA Brasch
Genome research 14 (10b), 2111-2120, 2004
1642004
Retrovirally Mediated Complementation of the glyBPhenotype: CLONING OF A HUMAN GENE ENCODING THE CARRIER FOR ENTRY OF FOLATES INTO MITOCHONDRIA
SA Titus, RG Moran
Journal of Biological Chemistry 275 (47), 36811-36817, 2000
1642000
The Drosophila erg K+ channel polypeptide is encoded by the seizure locus
SA Titus, JW Warmke, B Ganetzky
Journal of Neuroscience 17 (3), 875-881, 1997
1351997
The Eag Family of K+ Channels in Drosophila and Mammals
B Ganetzky, GA Robertson, GF Wilson, MC Trudeau, SA Titus
Annals of the New York Academy of Sciences 868 (1), 356-369, 1999
971999
A high-throughput imaging and nuclear segmentation analysis protocol for cleared 3D culture models
ME Boutin, TC Voss, SA Titus, K Cruz-Gutierrez, S Michael, M Ferrer
Scientific reports 8 (1), 11135, 2018
832018
Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays
DJ Urban, NJ Martinez, MI Davis, KR Brimacombe, DM Cheff, TD Lee, ...
Scientific reports 7 (1), 12758, 2017
802017
A mutation inactivating the mitochondrial inner membrane folate transporter creates a glycine requirement for survival of chinese hamster cells
EA McCarthy, SA Titus, SM Taylor, C Jackson-Cook, RG Moran
Journal of Biological Chemistry 279 (32), 33829-33836, 2004
782004
A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel
SA Titus, D Beacham, SA Shahane, N Southall, M Xia, R Huang, ...
Analytical biochemistry 394 (1), 30-38, 2009
702009
Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors
AP Skoumbourdis, CA LeClair, E Stefan, AG Turjanski, W Maguire, ...
Bioorganic & medicinal chemistry letters 19 (13), 3686-3692, 2009
632009
High-throughput fluorescence imaging approaches for drug discovery using in vitro and in vivo three-dimensional models
NJ Martinez, SA Titus, AK Wagner, A Simeonov
Expert opinion on drug discovery 10 (12), 1347-1361, 2015
602015
Mammalian mitochondrial and cytosolic folylpolyglutamate synthetase maintain the subcellular compartmentalization of folates
SA Lawrence, SA Titus, J Ferguson, AL Heineman, SM Taylor, RG Moran
Journal of Biological Chemistry 289 (42), 29386-29396, 2014
572014
Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein
I Al-Ramahi, SSP Giridharan, YC Chen, S Patnaik, N Safren, J Hasegawa, ...
elife 6, e29123, 2017
542017
Molecular analysis of murine leukemia cell lines resistant to 5, 10-dideazatetrahydrofolate identifies several amino acids critical to the function of folylpolyglutamate synthetase
R Zhao, S Titus, F Gao, RG Moran, ID Goldman
Journal of Biological Chemistry 275 (34), 26599-26606, 2000
522000
Functional analysis of a mouse brain Elk-type K+ channel
MC Trudeau, SA Titus, JL Branchaw, B Ganetzky, GA Robertson
Journal of Neuroscience 19 (8), 2906-2918, 1999
521999
Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channels
M Xia, SA Shahane, R Huang, SA Titus, E Shum, Y Zhao, N Southall, ...
Toxicology and applied pharmacology 252 (3), 250-258, 2011
452011
Canvass: A crowd-sourced, natural-product screening library for exploring biological space
SE Kearney, G Zahoránszky-Kőhalmi, KR Brimacombe, MJ Henderson, ...
ACS central science 4 (12), 1727-1741, 2018
372018
Neural stem cells for disease modeling and evaluation of therapeutics for infantile (CLN1/PPT1) and late infantile (CLN2/TPP1) neuronal ceroid lipofuscinoses
N Sima, R Li, W Huang, M Xu, J Beers, J Zou, S Titus, EA Ottinger, ...
Orphanet journal of rare diseases 13, 1-14, 2018
362018
Tissue-specific expression of functional isoforms of mouse folylpoly-γ-glutamate synthetase: a basis for targeting folate antimetabolites
FB Turner, JL Andreassi, J Ferguson, S Titus, A Tse, SM Taylor, ...
Cancer research 59 (24), 6074-6079, 1999
321999
A high-content assay enables the automated screening and identification of small molecules with specific ALDH1A1-inhibitory activity
A Yasgar, SA Titus, Y Wang, C Danchik, SM Yang, V Vasiliou, A Jadhav, ...
PLoS One 12 (1), e0170937, 2017
302017
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