Mario Bortolozzi
Mario Bortolozzi
University of Padua (Italy), department of Physics and Astronomy "G. Galilei"
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Ca2+ hot spots on the mitochondrial surface are generated by Ca2+ mobilization from stores, but not by activation of store-operated Ca2+ channels
M Giacomello, I Drago, M Bortolozzi, M Scorzeto, A Gianelle, P Pizzo, ...
Molecular cell 38 (2), 280-290, 2010
Presenilin 2 modulates endoplasmic reticulum (ER)–mitochondria interactions and Ca2+ cross-talk
E Zampese, C Fasolato, MJ Kipanyula, M Bortolozzi, T Pozzan, P Pizzo
Proceedings of the National Academy of Sciences 108 (7), 2777-2782, 2011
A novel deletion in the GTPase domain of OPA1 causes defects in mitochondrial morphology and distribution, but not in function
M Spinazzi, S Cazzola, M Bortolozzi, A Baracca, E Loro, A Casarin, ...
Human molecular genetics 17 (21), 3291-3302, 2008
A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness
R Ficarella, F Di Leva, M Bortolozzi, S Ortolano, F Donaudy, M Petrillo, ...
Proceedings of the National Academy of Sciences 104 (5), 1516-1521, 2007
The antidiabetic drug metformin blunts NETosis in vitro and reduces circulating NETosis biomarkers in vivo
L Menegazzo, V Scattolini, R Cappellari, BM Bonora, M Albiero, ...
Acta Diabetologica 55, 593-601, 2018
PDE2A2 regulates mitochondria morphology and apoptotic cell death via local modulation of cAMP/PKA signalling
S Monterisi, MJ Lobo, C Livie, JC Castle, M Weinberger, G Baillie, ...
elife 6, e21374, 2017
ATP-mediated cell–cell signaling in the organ of Corti: the role of connexin channels
P Majumder, G Crispino, L Rodriguez, CD Ciubotaru, F Anselmi, V Piazza, ...
Purinergic signalling 6, 167-187, 2010
Unitary permeability of gap junction channels to second messengers measured by FRET microscopy
VH Hernandez, M Bortolozzi, V Pertegato, M Beltramello, M Giarin, ...
Nature Methods 4 (4), 353-358, 2007
BAAV mediated GJB2 gene transfer restores gap junction coupling in cochlear organotypic cultures from deaf Cx26Sox10Cre mice
G Crispino, G Di Pasquale, P Scimemi, L Rodriguez, F Galindo Ramirez, ...
PloS one 6 (8), e23279, 2011
The human deafness-associated connexin 30 T5M mutation causes mild hearing loss and reduces biochemical coupling among cochlear non-sensory cells in knock-in mice
M SchŘtz, P Scimemi, P Majumder, RD De Siati, G Crispino, L Rodriguez, ...
Human molecular genetics 19 (24), 4759-4773, 2010
Ca2+ Signaling in the Inner Ear
F Mammano, M Bortolozzi, S Ortolano, F Anselmi
Physiology 22 (2), 131-144, 2007
The novel PMCA2 pump mutation Tommy impairs cytosolic calcium clearance in hair cells and links to deafness in mice
M Bortolozzi, M Brini, N Parkinson, G Crispino, P Scimemi, RD De Siati, ...
Journal of Biological Chemistry 285 (48), 37693-37703, 2010
The Novel Mouse Mutation Oblivion Inactivates the PMCA2 Pump and Causes Progressive Hearing Loss
SL Spiden, M Bortolozzi, F Di Leva, MH De Angelis, H Fuchs, D Lim, ...
PLoS genetics 4 (10), e1000238, 2008
Heterogeneity of Ca2+ handling among and within Golgi compartments
AKC Wong, P Capitanio, V Lissandron, M Bortolozzi, T Pozzan, P Pizzo
Journal of molecular cell biology 5 (4), 266-276, 2013
Phosphatases control PKA-dependent functional microdomains at the outer mitochondrial membrane
A Burdyga, NC Surdo, S Monterisi, G Di Benedetto, F Grisan, E Penna, ...
Proceedings of the National Academy of Sciences 115 (28), E6497-E6506, 2018
Reduced phosphatidylinositol 4, 5-bisphosphate synthesis impairs inner ear Ca2+ signaling and high-frequency hearing acquisition
L Rodriguez, E Simeonato, P Scimemi, F Anselmi, B Calý, G Crispino, ...
Proceedings of the National Academy of Sciences 109 (35), 14013-14018, 2012
What’s the function of connexin 32 in the peripheral nervous system?
M Bortolozzi
Frontiers in molecular neuroscience 11, 227, 2018
Molecular dynamics simulations highlight structural and functional alterations in deafness–related M34T mutation of connexin 26
F Zonta, D Buratto, C Cassini, M Bortolozzi, F Mammano
Frontiers in physiology 5, 85, 2014
Ca2+ signaling, apoptosis and autophagy in the developing cochlea: milestones to hearing acquisition
F Mammano, M Bortolozzi
Cell calcium 70, 117-126, 2018
Critical role of gap junction communication, calcium and nitric oxide signaling in bystander responses to focal photodynamic injury
B Calý, S Ceolin, F Ceriani, M Bortolozzi, AHR Agnellini, V Zorzi, ...
Oncotarget 6 (12), 10161, 2015
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