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Wouter Pos
Wouter Pos
PhD
Verified email at vectorytx.com - Homepage
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Cited by
Cited by
Year
In vivo discovery of immunotherapy targets in the tumour microenvironment
P Zhou, DR Shaffer, DA Alvarez Arias, Y Nakazaki, W Pos, AJ Torres, ...
Nature 506 (7486), 52-57, 2014
2532014
Crystal structure of the HLA-DM–HLA-DR1 complex defines mechanisms for rapid peptide selection
W Pos, DK Sethi, MJ Call, MSED Schulze, AK Anders, J Pyrdol, ...
Cell 151 (7), 1557-1568, 2012
1832012
Binding mode prediction of cytochrome P450 and thymidine kinase protein− ligand complexes by consideration of water and rescoring in automated docking
C De Graaf, P Pospisil, W Pos, G Folkers, NPE Vermeulen
Journal of medicinal chemistry 48 (7), 2308-2318, 2005
1722005
An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF
W Pos, JTB Crawley, R Fijnheer, J Voorberg, DA Lane, BM Luken
Blood, The Journal of the American Society of Hematology 115 (8), 1640-1649, 2010
1642010
Residues Arg568 and Phe592 contribute to an antigenic surface for anti-ADAMTS13 antibodies in the spacer domain
W Pos, N Sorvillo, R Fijnheer, HB Feys, PHP Kaijen, G Vidarsson, ...
haematologica 96 (11), 1670, 2011
1062011
Molecular mechanisms for contribution of MHC molecules to autoimmune diseases
LM Sollid, W Pos, KW Wucherpfennig
Current opinion in immunology 31, 24-30, 2014
972014
VH1‐69 germline encoded antibodies directed towards ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura
W Pos, BM Luken, EAM Turenhout, F Scheiflinger, JF Dong, R Fijnheer, ...
Journal of thrombosis and haemostasis 7 (3), 421-428, 2009
872009
Amino acid regions 572–579 and 657–666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP
BM Luken, EAM Turenhout, PHP Kaijen, MJ Greuter, W Pos, ...
Thrombosis and haemostasis 96 (09), 295-301, 2006
782006
Mechanisms of peptide repertoire selection by HLA-DM
W Pos, DK Sethi, KW Wucherpfennig
Trends in immunology 34 (10), 495-501, 2013
642013
The macrophage mannose receptor promotes uptake of ADAMTS13 by dendritic cells
N Sorvillo, W Pos, LM van den Berg, R Fijnheer, L Martinez-Pomares, ...
Blood, The Journal of the American Society of Hematology 119 (16), 3828-3835, 2012
582012
Humoral immune response to ADAMTS13 in acquired thrombotic thrombocytopenic purpura
W Pos, BM Luken, N Sorvillo, JAK Hovinga, J Voorberg
Journal of thrombosis and haemostasis 9 (7), 1285-1291, 2011
492011
Identification of N‐linked glycosylation and putative O‐fucosylation, C‐mannosylation sites in plasma derived ADAMTS13
N Sorvillo, PH Kaijen, M Matsumoto, Y Fujimura, C van der Zwaan, ...
Journal of Thrombosis and Haemostasis 12 (5), 670-679, 2014
362014
Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F
W Oosterheert, KT Xenaki, V Neviani, W Pos, S Doulkeridou, ...
Life Science Alliance 3 (11), 2020
212020
AT1412, a patient-derived antibody in development for the treatment of CD9 positive precursor B-acute lymphoblastic leukemia
G De Jong, SE Levie, R Schotte, W Pos, D Go, E Yasuda, M Cercel, ...
Blood 134, 4461, 2019
22019
580P AT1412, a patient-derived CD9 antibody promotes tumour immune infiltration and induces tumour rejection
R Schotte, J Villaudy, M Kedde, W Pos, K Wagner, D Go, C Fatmawati, ...
Annals of Oncology 31, S492, 2020
12020
582P Preclinical development of AT1412, a patient derived CD9 antibody that does not induce thrombosis for treatment of precursor B ALL
J Villaudy, R Schotte, G de Jong, V Neviani, W Pos, S Levie, E Yasuda, ...
Annals of Oncology 31, S493, 2020
12020
14 A patient derived antibody targeting the tetraspanin CD9 inhibits tumour progression and metastasis
R Schotte, J Villaudy, E Verdegaal, D Go, C Fatmawati, C Bru, ...
ESMO Open 3, A6-A7, 2018
12018
The role of MHC class II polymorphisms for DM-mediated peptide editing and autoimmunity
S Haag, W Pos, J Pyrdol, SK Dougan, KW Wucherpfennig
The Journal of Immunology 198 (1_Supplement), 156.24-156.24, 2017
12017
C-Type Lectin Receptor Mediated Immune Recognition of ADAMTS13 Promotes HLA-DRB1* 11 Dependent Presentation of CUB1-2 Derived Peptides by Dendritic Cells
N Sorvillo, SD van Haren, W Pos, E Herczenik, R Fijnheer, ...
Blood, The Journal of the American Society of Hematology 118 (21), 196-196, 2011
12011
Aml antigens and uses thereof
H Spits, MA GILLISSEN, M KEDDE, MD Hazenberg, PMW van HELDEN, ...
US Patent App. 18/050,272, 2023
2023
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