Anchored clathrate waters bind antifreeze proteins to ice CP Garnham, RL Campbell, PL Davies Proceedings of the National Academy of Sciences 108 (18), 7363-7367, 2011 | 427 | 2011 |
Calcium-bound structure of calpain and its mechanism of inhibition by calpastatin RA Hanna, RL Campbell, PL Davies Nature 456 (7220), 409-412, 2008 | 392 | 2008 |
Mutational and crystallographic analyses of the active site residues of the bacillus circulans xylanase WW Wakarchuk, RL Campbell, WL Sung, J Davoodi, M Yaguchi Protein Science 3 (3), 467-475, 1994 | 383 | 1994 |
Structure–function relationships in calpains RL Campbell, PL Davies Biochemical Journal 447 (3), 335-351, 2012 | 247 | 2012 |
Thermostabilization of the Bacillus circulansxylanase by the introduction of disulfide bonds WW Wakarchuk, WL Sung, RL Campbell, A Cunningham, DC Watson, ... Protein Engineering, Design and Selection 7 (11), 1379-1386, 1994 | 222 | 1994 |
An antifreeze protein folds with an interior network of more than 400 semi-clathrate waters T Sun, FH Lin, RL Campbell, JS Allingham, PL Davies Science 343 (6172), 795-798, 2014 | 203 | 2014 |
Crystal structure of human estrogenic 17β-hydroxysteroid dehydrogenase complexed with 17β-estradiol A Azzi, PH Rehse, DW Zhu, RL Campbell, F Labrie, SX Lin Nature structural biology 3 (8), 665-668, 1996 | 201 | 1996 |
A Ca2+-dependent bacterial antifreeze protein domain has a novel β-helical ice-binding fold CP Garnham, JA Gilbert, CP Hartman, RL Campbell, J Laybourn-Parry, ... Biochemical Journal 411 (1), 171-180, 2008 | 186 | 2008 |
26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity. PD Jeffrey, RK Strong, LC Sieker, CY Chang, RL Campbell, GA Petsko, ... Proceedings of the National Academy of Sciences 90 (21), 10310-10314, 1993 | 169 | 1993 |
Antifreeze protein from freeze-tolerant grass has a beta-roll fold with an irregularly structured ice-binding site AJ Middleton, CB Marshall, F Faucher, M Bar-Dolev, I Braslavsky, ... Journal of molecular biology 416 (5), 713-724, 2012 | 163 | 2012 |
Novel dimeric β-helical model of an ice nucleation protein with bridged active sites CP Garnham, RL Campbell, VK Walker, PL Davies BMC structural biology 11, 1-12, 2011 | 151 | 2011 |
A concerted, rational design of type 1 17β‐hydroxysteroid dehydrogenase inhibitors: estradiol‐adenosine hybrids with high affinity W Qiu, RL Campbell, A Gangloff, P Dupuis, RP Boivin, MR Tremblay, ... The FASEB Journal 16 (13), 1-26, 2002 | 114 | 2002 |
Crystal structures of calpain–E64 and–leupeptin inhibitor complexes reveal mobile loops gating the active site T Moldoveanu, RL Campbell, D Cuerrier, PL Davies Journal of molecular biology 343 (5), 1313-1326, 2004 | 110 | 2004 |
Genetic model of selective COX2 inhibition reveals novel heterodimer signaling Y Yu, J Fan, XS Chen, D Wang, AJ Klein-Szanto, RL Campbell, ... Nature medicine 12 (6), 699-704, 2006 | 102 | 2006 |
Three-dimensional structure of murine anti-p-azophenylarsonate Fab 36-71. 1. X-ray crystallography, site-directed mutagenesis, and modeling of the complex with hapten RK Strong, R Campbell, DR Rose, GA Petsko, J Sharon, MN Margolies Biochemistry 30 (15), 3739-3748, 1991 | 101 | 1991 |
Structure of a 1.5-MDa adhesin that binds its Antarctic bacterium to diatoms and ice S Guo, CA Stevens, TDR Vance, LLC Olijve, LA Graham, RL Campbell, ... Science advances 3 (8), e1701440, 2017 | 100 | 2017 |
Solution of a protein crystal structure with a model obtained from NMR interproton distance restraints AT Brünger, RL Campbell, GM Clore, AM Gronenborn, M Karplus, ... Science 235 (4792), 1049-1053, 1987 | 88 | 1987 |
Structural modeling of snow flea antifreeze protein FH Lin, LA Graham, RL Campbell, PL Davies Biophysical journal 92 (5), 1717-1723, 2007 | 85 | 2007 |
Molecular modeling of the human multidrug resistance protein 1 (MRP1/ABCC1) MK DeGorter, G Conseil, RG Deeley, RL Campbell, SPC Cole Biochemical and biophysical research communications 365 (1), 29-34, 2008 | 81 | 2008 |
Dehydroepiandrosterone and dihydrotestosterone recognition by human estrogenic 17β-hydroxysteroid dehydrogenase: C-18/C-19 steroid discrimination and enzyme-induced strain Q Han, RL Campbell, A Gangloff, YW Huang, SX Lin Journal of Biological Chemistry 275 (2), 1105-1111, 2000 | 78 | 2000 |