Joel Sussman

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Dan S TawfikWeizmann Institue of ScienceVerified email at weizmann.ac.il
Felix FrolowProfessor of Structural Biology and BiotechnologyVerified email at post.tau.ac.il
Hay Dvir, Ph.D.Institute of Animal Science, ARO Volcani InstituteVerified email at volcani.agri.gov.il
martin weikInstitut de Biologie Structurale, Grenoble, FranceVerified email at ibs.fr
Raimond RavelliMaastricht UniversityVerified email at maastrichtuniversity.nl
moshe goldsmithAssociate Staff Scientist, Weizmann Institute of ScienceVerified email at weizmann.ac.il
Tzviya ZeevUtrecht UniversityVerified email at uu.nl
Jacques-Philippe ColletierDirecteur de recherche, CNRS (DR2)Verified email at ibs.fr
Nadrian C. SeemanNew York University Verified email at nyu.edu
Dawei LinNIHVerified email at nih.gov
Paul H. AxelsenUniversity of PennsylvaniaVerified email at upenn.edu
Miroslaw CyglerUniversity of Saskatchewan, College of Medicine, Dept of Biochem, Microbiol & ImmunolVerified email at usask.ca
Amir AharoniProfessor for BiochemistryVerified email at bgu.ac.il
Aviv PazHauptman-Woodward Medical Research InstituteVerified email at hwi.buffalo.edu
moshe ben-DavidPostdoctoral fellow at the Donnelley Centre- CCBR, University of TorontoVerified email at utoronto.ca
Piet GrosBijvoet Center, Utrecht Life Science, Utrecht University, The NetherlandsVerified email at uu.nl
Menachem ShohamEmeritus Associate Professor of Biochemistry, Case Western Reserve UniversityVerified email at case.edu
George ChurchHarvard Medical SchoolVerified email at harvard.edu
Oded LivnahVerified email at mail.huji.ac.il
David OllisProfessor of Biological Chemistry, Australian National UniversityVerified email at anu.edu.au

Joel Sussman

Weizmann Institute of Science

Verified email at weizmann.ac.il - Homepage

Structural Biology


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Atomic Structure of Acetyicholinesterase from JL Sussman, M Harel, F Frolow, C Oefner, A Goldman, L Toker, I Silman Science 253 (5022), 872-879, 1991	3480	1991
The α/β hydrolase fold DL Ollis, E Cheah, M Cygler, B Dijkstra, F Frolow, SM Franken, M Harel, ... Protein Engineering, Design and Selection 5 (3), 197-211, 1992	2836	1992
FoldIndex©: a simple tool to predict whether a given protein sequence is intrinsically unfolded J Prilusky, CE Felder, T Zeev-Ben-Mordehai, EH Rydberg, O Man, ... Bioinformatics 21 (16), 3435-3438, 2005	1181	2005
Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase. M Harel, I Schalk, L Ehret-Sabatier, F Bouet, M Goeldner, C Hirth, ... Proceedings of the National Academy of Sciences 90 (19), 9031-9035, 1993	1181	1993
Three-dimensional tertiary structure of yeast phenylalanine transfer RNA SH Kim, FL Suddath, GJ Quigley, A McPherson, JL Sussman, AHJ Wang, ... Science 185 (4149), 435-440, 1974	1153	1974
Function and structure of inherently disordered proteins AK Dunker, I Silman, VN Uversky, JL Sussman Current opinion in structural biology 18 (6), 756-764, 2008	1151	2008
Protein production and purification Architecture et Fonction des Macromolécules Biologiques Vincentelli Renaud 4 ... Nature methods 5 (2), 135-146, 2008	1009	2008
Acetylcholinesterase: from 3D structure to function H Dvir, I Silman, M Harel, TL Rosenberry, JL Sussman Chemico-biological interactions 187 (1-3), 10-22, 2010	943	2010
Structure of acetylcholinesterase complexed with E2020 (Aricept®): implications for the design of new anti-Alzheimer drugs G Kryger, I Silman, JL Sussman Structure 7 (3), 297-307, 1999	928	1999
Three-dimensional structures of avidin and the avidin-biotin complex. O Livnah, EA Bayer, M Wilchek, JL Sussman Proceedings of the National Academy of Sciences 90 (11), 5076-5080, 1993	918	1993
Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes M Harel, A Aharoni, L Gaidukov, B Brumshtein, O Khersonsky, R Meged, ... Nature structural & molecular biology 11 (5), 412-419, 2004	885	2004
Protein Data Bank (PDB): database of three-dimensional structural information of biological macromolecules JL Sussman, D Lin, J Jiang, NO Manning, J Prilusky, O Ritter, EE Abola Acta Crystallographica Section D: Biological Crystallography 54 (6), 1078-1084, 1998	852	1998
The pitch of chromatin DNA is reflected in its nucleotide sequence. EN Trifonov, JL Sussman Proceedings of the National Academy of Sciences 77 (7), 3816-3820, 1980	762	1980
Relationship between sequence conservation and three‐dimensional structure in a large family of esterases, lipases, and related proteins M Cygler, JD Schrag, JL Sussman, M Harel, I Silman, MK Gentry, ... Protein Science 2 (3), 366-382, 1993	737	1993
Acetylcholinesterase:‘classical’and ‘non-classical’functions and pharmacology I Silman, JL Sussman Current opinion in pharmacology 5 (3), 293-302, 2005	670	2005
Specific chemical and structural damage to proteins produced by synchrotron radiation M Weik, RBG Ravelli, G Kryger, S McSweeney, ML Raves, M Harel, ... Proceedings of the National Academy of Sciences 97 (2), 623-628, 2000	625	2000
Structure of acetylcholinesterase complexed with the nootropic alkaloid,(–)-huperzine A ML Raves, M Harel, YP Pang, I Silman, AP Kozikowski, JL Sussman Nature structural biology 4 (1), 57-63, 1997	560	1997
Automated structure-and sequence-based design of proteins for high bacterial expression and stability A Goldenzweig, M Goldsmith, SE Hill, O Gertman, P Laurino, Y Ashani, ... Molecular cell 63 (2), 337-346, 2016	532	2016
Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system Y Shaaltiel, D Bartfeld, S Hashmueli, G Baum, E Brill‐Almon, G Galili, ... Plant biotechnology journal 5 (5), 579-590, 2007	490	2007
The X-ray structure of a transition state analog complex reveals the molecular origins of the catalytic power and substrate specificity of acetylcholinesterase M Harel, DM Quinn, HK Nair, I Silman, JL Sussman Journal of the American Chemical Society 118 (10), 2340-2346, 1996	447	1996

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