DENV inhibits type I IFN production in infected cells by cleaving human STING S Aguirre, AM Maestre, S Pagni, JR Patel, T Savage, D Gutman, ... Public Library of Science 8 (10), e1002934, 2012 | 578 | 2012 |
Inhibition of the type I interferon response in human dendritic cells by dengue virus infection requires a catalytically active NS2B3 complex JR Rodriguez-Madoz, A Belicha-Villanueva, D Bernal-Rubio, J Ashour, ... Journal of virology 84 (19), 9760-9774, 2010 | 203 | 2010 |
Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers X Agirre, G Castellano, M Pascual, S Heath, M Kulis, V Segura, ... Genome research 25 (4), 478-487, 2015 | 165 | 2015 |
Dengue virus inhibits the production of type I interferon in primary human dendritic cells JR Rodriguez-Madoz, D Bernal-Rubio, D Kaminski, K Boyd, ... Journal of virology 84 (9), 4845-4850, 2010 | 164 | 2010 |
Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies E San José-Enériz, X Agirre, O Rabal, A Vilas-Zornoza, JA Sanchez-Arias, ... Nature communications 8 (1), 15424, 2017 | 156 | 2017 |
Semliki forest virus vectors engineered to express higher IL-12 levels induce efficient elimination of murine colon adenocarcinomas JR Rodriguez-Madoz, J Prieto, C Smerdou Molecular Therapy 12 (1), 153-163, 2005 | 105 | 2005 |
CRISPR/Cas9-mediated glycolate oxidase disruption is an efficacious and safe treatment for primary hyperoxaluria type I N Zabaleta, M Barberia, C Martin-Higueras, N Zapata-Linares, I Betancor, ... Nature communications 9 (1), 5454, 2018 | 77 | 2018 |
Semliki forest virus expressing interleukin-12 induces antiviral and antitumoral responses in woodchucks with chronic viral hepatitis and hepatocellular carcinoma JR Rodriguez-Madoz, KH Liu, JI Quetglas, M Ruiz-Guillen, I Otano, ... Journal of Virology 83 (23), 12266-12278, 2009 | 57 | 2009 |
Increased efficacy and safety in the treatment of experimental liver cancer with a novel adenovirus-alphavirus hybrid vector M Guan, JR Rodriguez-Madoz, P Alzuguren, C Gomar, MG Kramer, ... Cancer research 66 (3), 1620-1629, 2006 | 56 | 2006 |
CAR density influences antitumoral efficacy of BCMA CAR T cells and correlates with clinical outcome P Rodriguez-Marquez, ME Calleja-Cervantes, G Serrano, A Oliver-Caldes, ... Science Advances 8 (39), eabo0514, 2022 | 53 | 2022 |
Neuregulin-1β induces mature ventricular cardiac differentiation from induced pluripotent stem cells contributing to cardiac tissue repair O Iglesias-Garcia, S Baumgartner, L Macri-Pellizzeri, ... Stem cells and development 24 (4), 484-496, 2015 | 52 | 2015 |
Cryopreservation of microencapsulated murine mesenchymal stem cells genetically engineered to secrete erythropoietin H Gurruchaga, J Ciriza, LS Del Burgo, JR Rodriguez-Madoz, E Santos, ... International journal of pharmaceutics 485 (1-2), 15-24, 2015 | 50 | 2015 |
Strict requirement for vector-induced type I interferon in efficacious antitumor responses to virally encoded IL12 I Melero, JI Quetglas, M Reboredo, J Dubrot, JR Rodriguez-Madoz, ... Cancer research 75 (3), 497-507, 2015 | 49 | 2015 |
Treatment of chronic viral hepatitis in woodchucks by prolonged intrahepatic expression of interleukin-12 J Crettaz, I Otano, L Ochoa, A Benito, A Paneda, I Aurrekoetxea, ... Journal of Virology 83 (6), 2663-2674, 2009 | 46 | 2009 |
Chromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma R Ordoñez, M Kulis, N Russiñol, V Chapaprieta, A Carrasco-Leon, ... Genome research 30 (9), 1217-1227, 2020 | 43 | 2020 |
Development of a new noncytopathic Semliki Forest virus vector providing high expression levels and stability E Casales, JR Rodriguez-Madoz, M Ruiz-Guillen, N Razquin, Y Cuevas, ... Virology 376 (1), 242-251, 2008 | 34 | 2008 |
Small molecule-based enzyme inhibitors in the treatment of primary hyperoxalurias MD Moya-Garzon, JA Gomez-Vidal, A Alejo-Armijo, J Altarejos, ... Journal of Personalized Medicine 11 (2), 74, 2021 | 27 | 2021 |
A novel system for the production of high levels of functional human therapeutic proteins in stable cells with a Semliki Forest virus noncytopathic vector E Casales, A Aranda, JI Quetglas, M Ruiz-Guillen, JR Rodriguez-Madoz, ... New biotechnology 27 (2), 138-148, 2010 | 27 | 2010 |
Eradication of liver-implanted tumors by Semliki Forest virus expressing IL-12 requires efficient long-term immune responses JI Quetglas, JR Rodriguez-Madoz, J Bezunartea, M Ruiz-Guillen, ... The Journal of Immunology 190 (6), 2994-3004, 2013 | 26 | 2013 |
Recombinant influenza A viruses with enhanced levels of PB1 and PA viral protein expression A Belicha-Villanueva, JR Rodriguez-Madoz, J Maamary, A Baum, ... Journal of virology 86 (10), 5926-5930, 2012 | 25 | 2012 |