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Jagan Muppidi
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Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction
JR Muppidi, J Tschopp, RM Siegel
Immunity 21 (4), 461-465, 2004
4172004
Loss of signalling via Gα13 in germinal centre B-cell-derived lymphoma
JR Muppidi, R Schmitz, JA Green, W Xiao, AB Larsen, SE Braun, J An, ...
Nature 516 (7530), 254-258, 2014
3062014
Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death
JR Muppidi, RM Siegel
Nature immunology 5 (2), 182-189, 2004
2832004
Abnormal disulfide-linked oligomerization results in ER retention and altered signaling by TNFR1 mutants in TNFR1-associated periodic fever syndrome (TRAPS)
AA Lobito, FC Kimberley, JR Muppidi, H Komarow, AJ Jackson, KM Hull, ...
Blood 108 (4), 1320-1327, 2006
2782006
SPOTS: signaling protein oligomeric transduction structures are early mediators of death receptor–induced apoptosis at the plasma membrane
RM Siegel, JR Muppidi, M Sarker, A Lobito, M Jen, D Martin, SE Straus, ...
The Journal of cell biology 167 (4), 735-744, 2004
1912004
Cannabinoid receptor 2 positions and retains marginal zone B cells within the splenic marginal zone
JR Muppidi, TI Arnon, Y Bronevetsky, N Veerapen, M Tanaka, GS Besra, ...
Journal of Experimental Medicine 208 (10), 1941-1948, 2011
822011
S-Geranylgeranyl-l-glutathione is a ligand for human B cell-confinement receptor P2RY8
E Lu, FD Wolfreys, JR Muppidi, Y Xu, JG Cyster
Nature 567 (7747), 244-248, 2019
682019
Homotypic FADD interactions through a conserved RXDLL motif are required for death receptor-induced apoptosis
JR Muppidi, AA Lobito, M Ramaswamy, JK Yang, L Wang, H Wu, ...
Cell Death & Differentiation 13 (10), 1641-1650, 2006
662006
The G protein–coupled receptor P2RY8 and follicular dendritic cells promote germinal center confinement of B cells, whereas S1PR3 can contribute to their dissemination
JR Muppidi, E Lu, JG Cyster
Journal of Experimental Medicine 212 (13), 2213-2222, 2015
562015
Cutting edge: Rac GTPases sensitize activated T cells to die via Fas
M Ramaswamy, C Dumont, AC Cruz, JR Muppidi, TS Gomez, ...
The Journal of Immunology 179 (10), 6384-6388, 2007
522007
The cholesterol metabolite 25-hydroxycholesterol restrains the transcriptional regulator SREBP2 and limits intestinal IgA plasma cell differentiation
BC Trindade, S Ceglia, A Berthelette, F Raso, K Howley, JR Muppidi, ...
Immunity 54 (10), 2273-2287. e6, 2021
422021
Rewiring of B cell receptor signaling by Epstein–Barr virus LMP2A
K Fish, F Comoglio, AL Shaffer III, Y Ji, KT Pan, S Scheich, A Oellerich, ...
Proceedings of the National Academy of Sciences 117 (42), 26318-26327, 2020
372020
Clathrin light chains’ role in selective endocytosis influences antibody isotype switching
S Wu, SR Majeed, TM Evans, MD Camus, NML Wong, Y Schollmeier, ...
Proceedings of the National Academy of Sciences 113 (35), 9816-9821, 2016
342016
TGFβ signaling in germinal center B cells promotes the transition from light zone to dark zone
AR Albright, J Kabat, M Li, F Raso, A Reboldi, JR Muppidi
Journal of Experimental Medicine 216 (11), 2531-2545, 2019
242019
Compromised counterselection by FAS creates an aggressive subtype of germinal center lymphoma
R Razzaghi, S Agarwal, N Kotlov, O Plotnikova, K Nomie, DW Huang, ...
Journal of Experimental Medicine 218 (3), e20201173, 2020
232020
Phase 1b/2 study of vipor (venetoclax, ibrutinib, prednisone, obinutuzumab, and lenalidomide) in relapsed/refractory B-cell lymphoma: safety, efficacy and molecular analysis
C Melani, R Lakhotia, S Pittaluga, MD Miljkovic, JD Phelan, JR Muppidi, ...
Blood 136, 44-45, 2020
202020
A multi-scale, multiomic atlas of human normal and follicular lymphoma lymph nodes
AJ Radtke, E Postovalova, A Varlamova, A Bagaev, M Sorokina, ...
BioRxiv, 2022.06. 03.494716, 2022
132022
Aberrant expansion of spontaneous splenic germinal centers induced by hallmark genetic lesions of aggressive lymphoma
GM Pindzola, R Razzaghi, RN Tavory, HT Nguyen, VM Morris, M Li, ...
Blood, The Journal of the American Society of Hematology 140 (10), 1119-1131, 2022
122022
A prospective study of clonal evolution in follicular lymphoma: circulating tumor DNA correlates with overall tumor burden and fluctuates over time without therapy
A Distler, R Lakhotia, JD Phelan, S Pittaluga, C Melani, JR Muppidi, ...
Blood 138 (Supplement 1), 1328-1328, 2021
82021
Preliminary results of a response-adapted study of ibrutinib and isavuconazole with temozolomide, etoposide, liposomal doxorubicin, dexamethasone, rituximab (TEDDI-R) for …
J Simard, C Melani, R Lakhotia, MS Lionakis, S Pittaluga, JD Phelan, ...
Blood 136, 24-25, 2020
82020
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