| The MDM2-p53 pathway revisited S Nag, J Qin, KS Srivenugopal, M Wang, R Zhang Journal of biomedical research 27 (4), 254, 2013 | 422 | 2013 |
| Ginsenosides as anticancer agents: in vitro and in vivo activities, structure-activity relationships, and molecular mechanisms of action SA Nag, J Qin, W Wang, MH Wang, H Wang, R Zhang Frontiers in pharmacology 3, 25, 2012 | 352 | 2012 |
| STAT3 as a potential therapeutic target in triple negative breast cancer: a systematic review JJ Qin, L Yan, J Zhang, WD Zhang Journal of Experimental & Clinical Cancer Research 38 (1), 195, 2019 | 321 | 2019 |
| Long non-coding RNAs towards precision medicine in gastric cancer: early diagnosis, treatment, and drug resistance L Yuan, ZY Xu, SM Ruan, S Mo, JJ Qin, XD Cheng Molecular Cancer 19 (1), 96, 2020 | 219 | 2020 |
| PROTAC: an effective targeted protein degradation strategy for cancer therapy SM Qi, J Dong, ZY Xu, XD Cheng, WD Zhang, JJ Qin Frontiers in Pharmacology 12, 692574, 2021 | 175 | 2021 |
| Medicinal Chemistry Strategies to Discover P-glycoprotein Inhibitors: An Update J Dong, Z Qin, WD Zhang, G Cheng, YG Assaraf, CJR Ashby, ZS Chen, ... Drug Resistance Updates 49, 100681, 2020 | 172 | 2020 |
| NFAT as cancer target: mission possible? JJ Qin, S Nag, W Wang, J Zhou, WD Zhang, H Wang, R Zhang Biochimica Et Biophysica Acta (BBA)-Reviews on Cancer 1846 (2), 297-311, 2014 | 151 | 2014 |
| Polycomb group (PcG) proteins and human cancers: multifaceted functions and therapeutic implications W Wang, JJ Qin, S Voruganti, S Nag, J Zhou, R Zhang Medicinal research reviews 35 (6), 1220-1267, 2015 | 132 | 2015 |
| Inula sesquiterpenoids: structural diversity, cytotoxicity and anti-tumor activity GW Wang, JJ Qin, XR Cheng, YH Shen, L Shan, HZ Jin, WD Zhang Expert opinion on investigational drugs 23 (3), 317-345, 2014 | 119 | 2014 |
| Japonicones A–D, bioactive dimeric sesquiterpenes from Inula japonica Thunb. JJ Qin, HZ Jin, JJ Fu, XJ Hu, Y Wang, SK Yan, WD Zhang Bioorganic & Medicinal Chemistry Letters 19 (3), 710-713, 2009 | 105 | 2009 |
| Natural Product Ginsenoside 25-OCH3-PPD Inhibits Breast Cancer Growth and Metastasis through Down-Regulating MDM2 W Wang, X Zhang, JJ Qin, S Voruganti, SA Nag, MH Wang, H Wang, ... PLoS One 7 (7), e41586, 2012 | 96 | 2012 |
| Chemical constituents of plants from the genus Dracocephalum. Q Zeng, HZ Jin, JJ Qin, JJ Fu, XJ Hu, JH Liu, L Yan, M Chen, WD Zhang Chemistry & Biodiversity 7 (8), 1911-1929, 2010 | 96 | 2010 |
| Recent update on development of small-molecule STAT3 inhibitors for cancer therapy: from phosphorylation inhibition to protein degradation J Dong, XD Cheng, WD Zhang, JJ Qin Journal of Medicinal Chemistry 64 (13), 8884-8915, 2021 | 94 | 2021 |
| The pyrido[b]indole MDM2 inhibitor SP-141 exerts potent therapeutic effects in breast cancer models W Wang, JJ Qin, S Voruganti, KS Srivenugopal, S Nag, S Patil, H Sharma, ... Nature communications 5 (1), 5086, 2014 | 92 | 2014 |
| Natural products targeting the p53-MDM2 pathway and mutant p53: recent advances and implications in cancer medicine JJ Qin, X Li, C Hunt, W Wang, H Wang, R Zhang Genes & diseases 5 (3), 204-219, 2018 | 90 | 2018 |
| Targeting USP7-Mediated Deubiquitination of MDM2/MDMX-p53 Pathway for Cancer Therapy: Are We There Yet? SM Qi, G Cheng, XD Cheng, Z Xu, B Xu, WD Zhang, JJ Qin Frontiers in Cell and Developmental Biology 8, 233, 2020 | 81 | 2020 |
| Targeting KRAS mutant cancers: from druggable therapy to drug resistance C Zhu, X Guan, X Zhang, X Luan, Z Song, X Cheng, W Zhang, JJ Qin Molecular Cancer 21 (1), 159, 2022 | 79 | 2022 |
| Identification of a new class of MDM2 inhibitor that inhibits growth of orthotopic pancreatic tumors in mice W Wang, JJ Qin, S Voruganti, MH Wang, H Sharma, S Patil, J Zhou, ... Gastroenterology 147 (4), 893-902. e2, 2014 | 78 | 2014 |
| Dual roles and therapeutic potential of Keap1-Nrf2 pathway in pancreatic cancer: a systematic review JJ Qin, XD Cheng, J Zhang, WD Zhang Cell Communication and Signaling 17, 1-15, 2019 | 77 | 2019 |
| New sesquiterpenes from Inula japonica Thunb. with their inhibitory activities against LPS-induced NO production in RAW264. 7 macrophages JJ Qin, HZ Jin, JX Zhu, JJ Fu, Q Zeng, XR Cheng, Y Zhu, L Shan, ... Tetrahedron 66 (48), 9379-9388, 2010 | 76 | 2010 |
Ruiwen ZhangProfessor of Pharmacology and Toxicology, Robert L. Boblitt Endowed Professor in Drug DiscoveryVerified email at central.uh.edu
