Genetic effects on gene expression across human tissues GTEx Consortium Lead analysts: Aguet François 1 Brown Andrew A. 2 3 4 Castel ... Nature 550 (7675), 204-213, 2017 | 3286 | 2017 |
Dynamic landscape and regulation of RNA editing in mammals MH Tan, Q Li, R Shanmugam, R Piskol, J Kohler, AN Young, KI Liu, ... Nature 550 (7675), 249-254, 2017 | 531 | 2017 |
Direct GR binding sites potentiate clusters of TF binding across the human genome CM Vockley, AM D’Ippolito, IC McDowell, WH Majoros, A Safi, L Song, ... Cell 166 (5), 1269-1281. e19, 2016 | 189 | 2016 |
Co-expression networks reveal the tissue-specific regulation of transcription and splicing A Saha, Y Kim, ADH Gewirtz, B Jo, C Gao, IC McDowell, BE Engelhardt, ... Genome research 27 (11), 1843-1858, 2017 | 165 | 2017 |
Clustering gene expression time series data using an infinite Gaussian process mixture model IC McDowell, D Manandhar, CM Vockley, AK Schmid, TE Reddy, ... PLoS computational biology 14 (1), e1005896, 2018 | 154 | 2018 |
Transversions have larger regulatory effects than transitions C Guo, IC McDowell, M Nodzenski, DM Scholtens, AS Allen, WL Lowe, ... Bmc Genomics 18, 1-9, 2017 | 124 | 2017 |
Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding IC McDowell, A Barrera, AM D'Ippolito, CM Vockley, LK Hong, ... Genome research 28 (9), 1272-1284, 2018 | 111 | 2018 |
Pre-established chromatin interactions mediate the genomic response to glucocorticoids AM D'Ippolito, IC McDowell, A Barrera, LK Hong, SM Leichter, LC Bartelt, ... Cell systems 7 (2), 146-160. e7, 2018 | 97 | 2018 |
Transcriptome of American oysters, Crassostrea virginica, in response to bacterial challenge: insights into potential mechanisms of disease resistance IC McDowell, C Nikapitiya, D Aguiar, CE Lane, S Istrail, M Gomez-Chiarri PLoS One 9 (8), e105097, 2014 | 84 | 2014 |
Context specific and differential gene co-expression networks via Bayesian biclustering C Gao, IC McDowell, S Zhao, CD Brown, BE Engelhardt PLoS computational biology 12 (7), e1004791, 2016 | 76 | 2016 |
Identifying cis-mediators for trans-eQTLs across many human tissues using genomic mediation analysis F Yang, J Wang, BL Pierce, LS Chen, F Aguet, KG Ardlie, BB Cummings, ... Genome research 27 (11), 1859-1871, 2017 | 67 | 2017 |
Local genetic effects on gene expression across 44 human tissues F Aguet, AA Brown, SE Castel, JR Davis, P Mohammadi, AV Segre, ... BioRxiv, 074450, 2016 | 64 | 2016 |
Multi-species protein similarity clustering reveals novel expanded immune gene families in the eastern oyster Crassostrea virginica IC McDowell, TH Modak, CE Lane, M Gomez-Chiarri Fish & shellfish immunology 53, 13-23, 2016 | 53 | 2016 |
Human genome-wide measurement of drug-responsive regulatory activity GD Johnson, A Barrera, IC McDowell, AM D’Ippolito, WH Majoros, ... Nature communications 9 (1), 5317, 2018 | 38 | 2018 |
Identification of potential general markers of disease resistance in American oysters, Crassostrea virginica through gene expression studies C Nikapitiya, IC McDowell, L Villamil, P Muñoz, SB Sohn, ... Fish & shellfish immunology 41 (1), 27-36, 2014 | 33 | 2014 |
Causal network inference from gene transcriptional time-series response to glucocorticoids J Lu, B Dumitrascu, IC McDowell, B Jo, A Barrera, LK Hong, SM Leichter, ... PLoS computational biology 17 (1), e1008223, 2021 | 30 | 2021 |
Genetic effects on gene expression across human tissues DA Laboratory, NIHC Fund, BCS Site—NDRI, BCS Site—RPCI, ... Nature 550 (7675), 204-213, 2017 | 23 | 2017 |
A long-range flexible billboard model of gene activation CM Vockley, IC McDowell, AM D'Ippolito, TE Reddy Transcription 8 (4), 261-267, 2017 | 16 | 2017 |
Distant regulatory effects of genetic variation in multiple human tissues B Jo, Y He, BJ Strober, P Parsana, F Aguet, AA Brown, SE Castel, ... BioRxiv, 074419, 2016 | 13 | 2016 |
Many long intergenic non-coding RNAs distally regulate mRNA gene expression levels IC McDowell, AA Pai, C Guo, CM Vockley, CD Brown, TE Reddy, ... bioRxiv, 044719, 2016 | 13 | 2016 |