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Design, synthesis, and biological evaluation of sirtinol analogues as class III histone/protein deacetylase (Sirtuin) inhibitors A Mai, S Massa, S Lavu, R Pezzi, S Simeoni, R Ragno, FR Mariotti, ... Journal of medicinal chemistry 48 (24), 7789-7795, 2005 | 213 | 2005 |
Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics M Hrabě de Angelis, G Nicholson, M Selloum, JK White, H Morgan, ... Nature genetics 47 (9), 969-978, 2015 | 148 | 2015 |
A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction MR Bowl, MM Simon, NJ Ingham, S Greenaway, L Santos, H Cater, ... Nature communications 8 (1), 886, 2017 | 144 | 2017 |
A resource of targeted mutant mouse lines for 5,061 genes MC Birling, A Yoshiki, DJ Adams, S Ayabe, AL Beaudet, J Bottomley, ... Nature genetics 53 (4), 416-419, 2021 | 90 | 2021 |
Jackson Laboratory. Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS) Charles River Laboratories. MRC Harwell. Toronto Centre for Phenogenomics. Wellcome … ME Dickinson, AM Flenniken, X Ji, L Teboul, MD Wong, JK White, ... Nature 537 (7621), 508-514, 2016 | 69 | 2016 |
HUVEC respond to radiation by inducing the expression of pro-angiogenic microRNAs S Vincenti, N Brillante, V Lanza, I Bozzoni, C Presutti, F Chiani, MP Etna, ... Radiation research 175 (5), 535-546, 2011 | 49 | 2011 |
A potent antagonist antibody targeting connexin hemichannels alleviates Clouston syndrome symptoms in mutant mice Y Kuang, V Zorzi, D Buratto, G Ziraldo, F Mazzarda, C Peres, C Nardin, ... EBioMedicine 57, 2020 | 32 | 2020 |
Functional loss of Ccdc151 leads to hydrocephalus in a mouse model of primary ciliary dyskinesia F Chiani, T Orsini, A Gambadoro, M Pasquini, S Putti, M Cirilli, ... Disease Models & Mechanisms 12 (8), dmm038489, 2019 | 26 | 2019 |
Organ-on-chip model shows that ATP release through connexin hemichannels drives spontaneous Ca 2+ signaling in non-sensory cells of the greater epithelial ridge in the … F Mazzarda, A D'Elia, R Massari, A De Ninno, FR Bertani, L Businaro, ... Lab on a Chip 20 (16), 3011-3023, 2020 | 25 | 2020 |
International Mouse Phenotyping C ME Dickinson, AM Flenniken, X Ji, L Teboul, MD Wong, JK White, ... Jackson L, Charles River L, Harwell MRC, Infrastructure Nationale Phenomin …, 2016 | 25 | 2016 |
SIR2 modifies histone H4-K16 acetylation and affects superhelicity in the ARS region of plasmid chromatin in Saccharomyces cerevisiae F Chiani, FD Felice, G Camilloni Nucleic acids research 34 (19), 5426-5437, 2006 | 22 | 2006 |
Three-dimensional microCT imaging of murine embryonic development from immediate post-implantation to organogenesis: application for phenotyping analysis of early embryonic … O Ermakova, T Orsini, A Gambadoro, F Chiani, GP Tocchini-Valentini Mammalian Genome 29, 245-259, 2018 | 21 | 2018 |
A human-derived monoclonal antibody targeting extracellular connexin domain selectively modulates hemichannel function G Ziraldo, D Buratto, Y Kuang, L Xu, A Carrer, C Nardin, F Chiani, ... Frontiers in physiology 10, 392, 2019 | 20 | 2019 |
Mouse Panx1 Is Dispensable for Hearing Acquisition and Auditory Function V Zorzi, F Paciello, G Ziraldo, C Peres, F Mazzarda, C Nardin, M Pasquini, ... Frontiers in molecular neuroscience 10, 379, 2017 | 20 | 2017 |
Radiation Genes: a database devoted to microarrays screenings revealing transcriptome alterations induced by ionizing radiation in mammalian cells F Chiani, C Iannone, R Negri, D Paoletti, M D’Antonio, PD De Meo, ... Database 2009, bap007, 2009 | 20 | 2009 |
Three-dimensional X-ray imaging of β-galactosidase reporter activity by micro-CT: Implication for quantitative analysis of gene expression O Ermakova, T Orsini, P Fruscoloni, F Chiani, A Gambadoro, S Putti, ... Brain Sciences 11 (6), 746, 2021 | 12 | 2021 |
Connexin hemichannel activation by S-nitrosoglutathione synergizes strongly with photodynamic therapy potentiating anti-tumor bystander killing C Nardin, C Peres, S Putti, T Orsini, C Colussi, F Mazzarda, M Raspa, ... Cancers 13 (20), 5062, 2021 | 10 | 2021 |
Correction: Corrigendum: High-throughput discovery of novel developmental phenotypes ME Dickinson, AM Flenniken, X Ji, L Teboul, MD Wong, JK White, ... Nature 551 (7680), 398-398, 2017 | 10 | 2017 |
Nucleosomes represent a physical barrier for cleavage activity of DNA topoisomerase I in vivo F Di Felice, F Chiani, G Camilloni Biochemical Journal 409 (3), 651-656, 2008 | 10 | 2008 |